biomedical research company in india

The five hottest private biotech companies in India

India is brimming with biotech companies and a young and skilled workforce. Here’s a quick glance at the private healthcare biotechs in India that captured investors’ imaginations in the last couple of years.

India has historically been known for its large IT, pharmaceutical and vaccine manufacturing sectors, but is also a force to be reckoned with in the global biotechnology market. The nation boasts around 5,000 biotech companies, with more than 4,000 being startups. This startup count is expected to reach 10,000 by 2024.

With a huge population of young and skilled workers, India has many ingredients for expanding the number of its biotech companies in the coming years. Add to this a large patient pool for lifestyle-related diseases such as type 2 diabetes, and there is a large potential for generating innovations in healthcare.

We’ve assembled a shortlist of the hottest private biotech companies in India by checking who’s raised impressive cash in the last few years. These companies are carrying out innovative healthcare research and are primarily based in Mumbai and Bengaluru.

Table of contents

Bugworks Research India Pvt Ltd

Founded: 2014

Headquarters: Bengaluru, India and Saratoga, U.S.

Bugworks has multiple sites in the U.S. and Australia with a research and development base in India. The firm specializes in the development of antibiotics that could address the growing crisis of antimicrobial resistance . 

Bugworks’ lead candidate antibiotic blocks the replication machinery in invading bacteria. In addition, the drug is designed to bypass normal resistance mechanisms in bacteria, which could make it harder for strains to become resistant to the treatment.

The company is testing its antibiotic in phase 1 trials for the treatment of multi-drug resistant infections in collaboration with the nonprofit initiatives CARB-X and the Global Antibiotic Research and Development Partnership ( GARDP ). 

Bugworks is financing its antibiotics research with a $18 million Series B1 round closed in February 2022. In addition, Bugworks will use the proceeds to fund the preclinical development of a dual-acting drug to treat cancer.

Epigeneres Biotech Private Limited

Founded: 2012

Headquarters: Mumbai

Epigeneres Biotech hit the headlines in January 2022 with a $6 million Series B funding round. The Indian biotech company is using the cash to develop a wide range of different technologies in its arsenal, including cancer tests, nanotechnology-based medicines and nutraceuticals.

Cancer detection is Epigeneres’ most recent pursuit. In 2021, the firm teamed up with the Singaporean company Tzar Labs to develop cancer diagnostics that screen for telltale RNA molecules from tumors at early stages of disease. Epigeneres is poised to launch a screening service in India based on the technology.

Epigeneres also has nucleic acid drugs in development for the treatment of conditions ranging from infertility to renal failure to autoimmune diseases. The firm uses a form of nanotechnology to boost the delivery of the drugs to the target cells.

In addition, Epigeneres is working on small molecule drugs that can increase the population of stem cells in the body in a regenerative medicine setting.

Founded: 2016

Headquarters: Bengaluru

In August 2022, Eyestem caught the eye of investors in a $6.4 million Series A round. The Indian biotech startup is working on cell therapies for eye disorders, with a flagship therapy in the pipeline for the treatment of dry age-related macular degeneration (dry AMD).

There is currently no treatment for dry AMD. In patients with the condition, the eye accumulates cellular debris, which causes destructive inflammation in the retina. This leads to a loss of retinal pigment epithelium, the layer of cells that support the photosensitive cells we need to see. 

Eyestem is developing an off-the-shelf stem cell therapy to replace lost retinal pigment epithelium. The biotech has earmarked money from its recent Series A round for preparing its cell therapy for early-stage clinical testing.

Immuneel Therapeutics Private Limited

Founded: 2019

Immuneel Therapeutics is making waves in the field of autologous CAR-T cell therapy , where a patient’s immune T cells are removed, engineered in the lab to kill blood cancer cells, and reinfused into the patient. There are CAR-T therapies already available, but these complex, expensive therapies are currently limited to only the wealthiest countries.

Immuneel’s mission is to develop CAR-T therapies that are accessible and affordable in India. To support this push, the company raised $15 million in June 2022 in a Series A round.

The therapies in Immuneel’s pipeline are targeted to various types of blood cancer in children and adult patients. As the Indian biotech closed its Series A round, Immuneel kicked off a phase 2 trial of a CAR-T therapy in what it claims is the first industry-sponsored CAR-T trial in India.

Founded: 2013

Headquarters: Bengaluru and Wilmington, U.S.

MedGenome has sites around the globe, with a large part of its operations and genetic testing situated in, and targeted to, India.

The company carries out genomics-focused research and diagnostics services for biopharma clients that can help in the development of drugs tackling cancer, diabetes, eye conditions and cardiovascular diseases. To provide a rich dataset, the company works with more than 500 hospitals in India.

MedGenome raised one of the Asia-Pacific region’s biggest biotech investments in August 2022 — a $50 million round led by Novo Holdings. The funds will be used to increase access to genetic testing in emerging markets, which have lagged behind the wealthier parts of the world. 

MedGenome also aims to collect genetic data from a wide range of populations in Asia, which could provide a treasure trove of clinical insights for genes related to disease. In keeping with this aim, the company is a founding member of the initiative GenomeAsia 100K , which will analyze the genomes of 100,000 people from a range of Asian populations to speed up the development of precision medicine in this part of the world.

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Top Core Companies for Biomedical Engineers in India

Even before the pandemic, drug manufacturing was indeed an important industry in the country. The expansion of the Indian domestic pharmaceutical market surpassed that of the entire economy by 2 to 3 percent every year. The pharmaceutical business in India has enormous untapped potential.

India’s goals for self-sufficiency have been most visible in the pharmaceutical industry. And biomedical engineers from around the country are making significant contributions towards this objective.

Today, we look at some of the top core companies offering opportunities for Biomedical Engineers in India.

The following are the Top Core Companies for Biomedical Engineers in India:

1. Serum Institute Of India

Serum Institute of India (SII) is a biotechnology and biopharmaceuticals company based in India. Cyrus Poonawalla established it, and it is a subsidiary of the Cyrus Poonawalla Group.

It is the world’s largest vaccine producer. The organisation has collaborated with AstraZeneca, a British-Swedish multinational pharmaceutical corporation that developed ‘Covishield’ in association with the University of Oxford.

Engaged in:

• Biopharmaceuticals
• Generic Drugs
• Over-the-counter Drugs

Established: 1966

Headquarters – Pune, Maharashtra, India

Number of Employees – 2,115

Headquarters Location – 212/2, Hadapsar, Off Soli Poonawalla Road, Pune – 411028, Maharashtra, India

2. Panacea Biotec Ltd.

Panacea Biotec is an Indian multinational manufacturer of generic and specialty pharmaceuticals as well as vaccines. It is one of India’s 3 key biotechnology enterprises.

The Russian Direct Investment Fund (RDIF) partnered with Panacea Biotec to manufacture the ‘Sputnik V’ Covid-19 vaccine in India. The business grew over time to emerge as one of India’s top vaccine producers.

• Pharmaceuticals

Established: 1984

Headquarters – New Delhi, India

Number of Employees – 2,564

Headquarters Location – B-1 Extn./ A-27, Mohan Co-op. Industrial Estate, Mathura Road – 110044, New Delhi, India

3. Medtronic

Medtronic plc is a medical device company based in the United States. Earl Bakken and his brother-in-law, Palmer Hermundslie, established Medtronic in Minneapolis as a medical devices repair business.

Medtronic was named the world’s largest medical equipment company in May 2018. While it is predominantly operating in the United States, it is functional in over 150 nations.

• Medical Devices

Established: 1949

Global Headquarters – Dublin, Ireland (legal) & Minneapolis, Minnesota, U.S.A.

Indian Headquarters – Mumbai, Maharashtra, India

Number of Employees – 95,000+

Global Headquarters Location – 710 Medtronic Parkway, Minneapolis, MN 55432-5604, U.S.A

Indian Headquarters Location – Solitaire C Park, 1241, Bldg. No.12, 6th floor, A.G. Link road, Chakala, Andheri-E, Mumbai – 400093, Maharashtra, India

4. Biocon Ltd.

Biocon Limited is a biopharmaceutical business based in India. Kiran Mazumdar-Shaw established it. The company produces generic active pharmaceutical ingredients (APIs), which are distributed in over 120 countries worldwide.

In 1979, it became the first Indian business to produce and sell enzymes to the American and European markets.

• Small Molecules
• Branded Formulations
• Research Services

Established: 1978

Headquarters – Bengaluru, Karnataka, India

Number of Employees – 9, 234

Headquarters Location – Biocon Limited, 20th KM, Hosur Road, Electronic City, Bengaluru – 560100, Karnataka, India

5. Shantha Biotech

Shantha Biotechnics Limited is a biotechnology corporation based in India. Shantha Biotechnics, Ltd. was founded by Dr. K. I. Varaprasad Reddy and Khalil Ahmed. The organisation is wholly owned by the Sanofi group.

It is India’s maiden enterprise to design, produce, and sell recombinant human healthcare solutions.

• Recombinant DNA

Established: 1993

Headquarters – Hyderabad, Telangana, India

Number of Employees – 806

Headquarters Location – 3rd & 4th Floor, H.No: 5-10-173, Fateh Maidan Road, Basheerbagh, Hyderabad – 500004, Telangana, India

6. Indian Immunologicals

The National Dairy Development Board owns Indian Immunologicals Limited (IIL). It is well-known for creating veterinary and human vaccinations for foot-and-mouth disease, rabies, and bacterial vaccinations, among other things.

IIL is a significant provider of DPT, TT, and Hepatitis B vaccinations to India’s massive Universal Immunisation Program. In India, IIL has 3 vaccine production plants.

• Anti-rabies Vaccine
• Theileriosis Vaccine
• Brucellosis Vaccine
• Porcine Vaccines
• SheepVaccines
• Bacterial Vaccines
• Nutraceuticals
• Formulations

Established: 1982

Number of Employees – 1,162

Headquarters Location – Road No. 44, Jubilee Hills, Hyderabad – 500033, Telangana, India

7. Dr. Reddy’s Laboratories Limited

Dr. Reddy’s Laboratories is a multinational pharmaceutical company based in India. The organisation was founded by Kallam Anji Reddy. Dr. Reddy’s started off by producing active pharmaceutical ingredients. Within just one year, Reddy’s became the very first Indian business to export pharmaceutical active ingredients to Europe.

The company manufactures around 190 drugs and 60 active pharmaceutical ingredients (APIs) for drug manufacturing, diagnostic devices, intensive care, and biotechnology.

• Diagnostics

Number of Employees – 21,650

Headquarters Location – 8-2-337, Road No. 3, Banjara Hills, Hyderabad, Telangana, India

8. Johnson & Johnson

Johnson & Johnson (J&J) is a multinational corporation based in the United States that manufactures medical equipment, medicines, and consumer packaged products. In 1886, Robert Wood Johnson partnered with his brothers, James Wood Johnson and Edward Mead Johnson, to develop a range of ready-to-use sterile surgical dressings. They established Johnson & Johnson.

It is placed No. 36 on the 2021 Fortune 500 list of the top companies in the United States by overall revenue. The corporation has around 250 subsidiary companies operating in 60 nations and selling products across over 175 nations.

• Consumer Health
• Medical Technology

Established: 1886

Global Headquarters – New Jersey, U.S.A.

Number of Employees – 1,44,500

Global Headquarters Location – One Johnson & Johnson Plaza, New Brunswick, New Jersey, U.S.A.

Indian Headquarters Location – 501 Arena Space, behind Majas Bus Depot, off Jogeshwari Vikhroli Link, Road Jogeshwari, Mumbai – 400060, Maharashtra, India

9. Sun Pharmaceuticals Industry Limited

Sun Pharma is among the best core biomedical companies in India. It is a multinational medical company based in India, with 70% of its revenue coming from markers in the USA and India.

Sun Pharma has multiple subsidiaries through which it supplies generic complexes, branded generics, antiretrovirals, and active pharmaceutical ingredients.

• Over-the-counter drugs
• Generic medicines
• Antiviral drugs
• Active pharmaceutical ingredients
• Drugs Manufacturing
• Medical Research and Development

Established: 1983

Headquarters – Mumbai, Maharashtra, India

Number of Employees – 37,000+

Headquarters Location – Sun House, CTS No. 201 B/1, Western Express Highway, Goregaon East, Mumbai – 400063, Maharashtra, India

10. Alkem Laboratories

Alkem Laboratories is one of the oldest and top biomedical engineering companies in India. It was founded by Samprada Singh in 1973.

The multinational pharmaceutical company manufactures and markets generic and over-the-counter drugs, vaccines, diagnostics, and animal healthcare products.

The company accumulated 1.3 billion USD in revenue while establishing 800+ renowned brands with a presence in 40+ countries. Today, the company has set up 19 manufacturing units in India and 2 in the USA.

• Animal Health Products

Established: 1973

Number of Employees – 15000+

Headquarters Location – Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai – 400013, Maharashtra, India

11. Aurobindo Pharma Limited

Aurobindo Pharma is an Indian multinational pharmaceutical manufacturing company that produces and markets various generic, branded generic, and over-the-counter medicines. P.V. Ramprasad Reddy and K. Nityananda Reddy founded Aurobindo Pharma in 1986.

Starting as a synthetic penicillin manufacturer in 1988–1989, it currently exports its products to 125+ nations. It also actively contributes to therapeutic segments like antiretrovirals, neurosciences, antibiotics, cardiovascular, anti-diabetics, and gastroenterology. Pfizer and AstraZeneca are among Aurobindo’s marketing partners.

• Research and Development
• Active Pharmaceutical Ingredients
• Biocatalysts
• Chemistry and Biotechnology Services

Established: 1986

Number of Employees – 24, 000+

Headquarters Location – Plot no. 2, Maitri Vihar, Ameerpet, Hyderabad – 500038, Telangana, India

12. GlaxoSmithKline Pharmaceuticals Ltd

GSK Pharmaceuticals is a multinational pharmaceutical and biotech company that markets and produces vaccines, medicines for special diseases, and prescription drugs. It operates in markets in the Middle East, Europe, Africa, Australia, Latin America, Russia, and India.

The UK-based biopharma company has 4 research and development centres across the world and is working in the fields of HIV, oncology, and immunology. With a revenue of over 29 billion euros, GSK is among the top biomedical engineering companies in India.

• Prescription Medicines
• Specialty Medicines
• Anti-smoking Supplements
• Nutritional Drinks

Established: 1924

Number of Employees – 70, 000

Headquarters Location – 252, Dr. Annie Besant road, Worli, Mumbai – 400030, Maharashtra, India

13. Lupin Limited

Lupin is an Indian multinational biomedical company that manufactures biotech products, pharmaceuticals, generic medicines, and drug delivery systems. Lupin was established by Desh Bandhu Gupta in 1968.

Its key therapeutic areas include respiratory diseases, tuberculosis, cardiovascular diseases, diabetes, dermatology, and ophthalmology. With such areas of expertise make it one of the top core companies for biomedical engineering interests.

Today its operations extend to over 100 countries across the globe, including the USA, Japan, and Europe as its major markets.

• Active Pharmaceutical Ingredients (APIs)
• Generic drugs
• Specialty drugs
• Biotechnology Products
• Research and development
• Advanced Drug Delivery System

Established: 1968

Number of Employees – 18, 302

Headquarters Location – 3rd Floor, Kalpataru Inspire, Off Western Express Highway, Santa Cruz East, Mumbai – 400055, Maharashtra, India

Final Words

We hope this article has helped you identify the top core companies for Biomedical Engineers in India. Feel free to reach out to us, if you have any questions or suggestions.

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Thirumoorthy

Thirumoorthy serves as a teacher and coach. He obtained a 99 percentile on the CAT. He cleared numerous IT jobs and public sector job interviews, but he still decided to pursue a career in education. He desires to elevate the underprivileged sections of society through education

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25 Best Biotech Companies in India (2023)

• Apr 28, 2023

Looking for biotechnology companies? Here are the top best biotech companies in India in terms of market cap, product range, net revenue, net assets, profits, and financial ratios.

The Department of Biotechnology was established in India under the Ministry of Science and Technology in the year 1986. The Indian Biotechnology industry was valued at $80.12 billion in 2022 and is expected to reach $150 billion by 2025 . ( Source: Invest India )

The Indian biotech industry comprises more than 2,700 Biotech Startups and 2,500+ Biotechnology companies in India. These are divided into five divisions namely, Bio-Agriculture, Bio-Pharmaceuticals, Bio-Services, Bio-Industrial, and Bio-IT.

Biopharmaceuticals contributed approximately 58% to the Indian Biotech market which was followed by Bio-Agriculture (19%) and Bio-Services (15%).

The Biotechnology Industry Research Assistance Council ( BIRAC ) was set up by the Department of Biotechnology intending to foster innovation and ensure the global competitiveness of the industry. In addition, 9 Biotech Parks and several incubators were set up by the Government of India to support research initiatives in Biotechnology.

The biotech companies mentioned in this list have contributed significantly to the Indian bio-pharma industry.

Read More: 11 Best Medical Devices Companies in India

Top Biotech Companies in India

Best biotech companies in india.

The biotech companies mentioned in this list are based on the products, market capitalization, assets, net profits, services, reviews from clients, revenue, turnover, and other financial ratios.

So without further ado, let’s take a closer look at the best Biotech companies in India in 2023.

1. GlaxoSmithKline Pharmaceuticals

GlaxoSmithKline Pharmaceuticals Ltd holds the #1 spot in vaccines company in the self-pay segment. The R&D pipeline of the country contains 37 potential new medicines and 15 new vaccines.

Top Pharma brands of GSK include Betnovate, Calpol, Augmentin, and Eltroxin. The company introduced prominent vaccines such as Synflorix and Rotarix.

GSK generates 83% of the total revenue from pharmaceuticals and 17% from vaccines.

• Headquarters: Mumbai, India
• Chairperson: R.S. Karnad
• Founded: 2000
• Total Permanent Employees: 4,364

2. Bharat Serums and Vaccines Limited

Bharat Serums and Vaccines Limited (BSV) is one the best biotech companies in India which is widely acclaimed to serve for more than 4 decades now. They have used scientific resources to develop a range of biological, biotech, and pharmaceutical products.

Today, they influence patient outcomes in the therapeutic areas of Women’s health and Critical Care, and IUI-IVF, and have the privilege of being a partner of choice.

With a registered corporate office in Navi Mumbai, their range of products is from various fields such as Gynecology, assisted reproductive technology, critical care, emergency medicine, neurology, nephrology & hematology, and urology.

3. Biocon Limited

Biocon is one of the largest biotechnology companies in India. The company focuses on continuous innovation to manufacture life-saving medicines at an affordable cost.

This is evident from the humongous amount of ₹5,271 million spent on R&D activities in the previous year.

Holding over 1220 patents, the company is working on its psoriasis biologic drug ALZUMAb™ in the fight against the global pandemic.

Biocon is one of the best biotech companies in India manufacturing Gliptins, Peptides, Anti-obesity, Immunosuppressants, Statins, Fungins, Multiple Sclerosis, and Oncology drugs.

• Headquarters : Bengaluru, India
• Executive Chairperson : Kiran Mazumdar Shaw
• CEO and Managing Director: Siddharth Mittal
• Founded : 1978
• Total Permanent Employees: 3,155

4. Dr. Reddy Laboratories Ltd

Dr. Reddy Laboratories is arguably one of the best biotech companies in India which was Incorporated in 1984 by the Scientist and Founder Dr. K Anji Reddy. The company was formed with the sole purpose to make medicines accessible to everyone.

Beginning with the manufacture of active ingredients (APIs) for Ibuprofen and then Methyldopa, the anti-hypertensive drug previously unavailable in India, the company later branched into formulations.

In 1988, it became the largest exporter of Ibuprofen API in India with sales to the US, Spain, Italy, and Japan. Over time it began to export active ingredients for Norfloxacin and Ciprofloxacin to Europe and the Far East in 1990 being the first Indian pharmaceutical company.

The common products are available under a brand name, such as Omez (Omeprazole), Nise (Nimesulide), Ketorol (Ketorolac Tromethamine), Stamlo (Amlodipine Besylate), Razo (Rabeprazole), among many others.

5. Jubilant Life Sciences Limited

Jubilant Pharma is arguably one of the best biotech companies in India having a presence in over 100 countries across the globe.

The product portfolio ranges from CVF, CNF, and anti-infective to anti-diabetic drugs. Aiming to reduce the environmental footprint, sustainability is a core aspect of their business.

The company has a Sustainability and CSR team in place for monitoring Social, Environment, and Economic progress.

• Headquarters : Uttar Pradesh, India
• Chairman: Shyam S Bhartia
• Total Permanent Employees: 6,643

6. AstraZeneca Pharma India Ltd 

AstraZeneca Pharma India is a biopharmaceutical organization whose Indian manufacturing facility has been rated as one of the finest in Southeast Asia.

Their core therapy areas include Cardiovascular, Renal & Metabolic Diseases, Oncology, Respiratory, Inflammation & Autoimmunity. A few note-worthy brands of the company are Forxiga, Brilinta, and Imfinzi.

• Chairman:  Narayan K Seshadri
• Founded : 1979
• Total Permanent Employees: 1,325

7. Bharat Biotech

Covaxin, a well-known product of Bharat Biotech is now a name known across the nation. Having over 160 patents in its name, the leading biotech company quickly aligned its processes to save the world.

They are the biggest rabies shot producer and have rolled out a business model tied to patient needs. To capture emerging markets, they are building a robust product pipeline to fuel long-term growth.

• Headquarters : Mumbai, India
• Executive Director & CEO: Vivek K. Agnihotri
• Founded : 1992
• Total Permanent Employees: 7,412 (2020)

8. Sun Pharma Advanced Research Company

Sun Pharma Advanced Research Company was formed when there was a corporate restructuring of Sum Pharma. The main focus of the company is innovation in therapeutics and delivery.

They aim to improve the standards of patient care through out-of-the-box thinking and ideation. Partnering with the University of Michigan in 2020, the organization plans to commence R&D for the development of new medicines.

• Chairman & Managing Director : Dilip S Shanghvi
• Non-Executive Director : Sudhir V Valia
• Founded : 2006
• Total Permanent Employees: 36,000+

9. Novozymes

Novozymes is one of the most reputed biotech companies in India it was founded in 1921 in Denmark and later moved across multiple continents and countries including India. The business model of the company is to form the framework for how they use resources to live up to the purpose, meet their long-term goals, and develop meaningful partnerships.

Their business is about turning science into sustainable biological solutions in a growing world. For that, they actively use enzymes and microorganisms as a starting point to unlock business opportunities.

From enabling farmers to feed animals more efficiently to creating greener, high-performing solutions for household cleaning, innovations are paving the way for a better tomorrow.

10. Syngene International Ltd.

Boasting a team of more than 4,200 scientists and 400+ patents, Syngene utilizes cutting-edge scientific research to nurture animal and human health. They have manufacturing facilities in Bengaluru and Mangaluru along with laboratories in Bengaluru and Hyderabad.

The company’s R&D and manufacturing facilities provide scientific services to the following sectors namely: Animal Health, Consumer Goods, Pharmaceutical, Biotechnology, Speciality Chemical Companies, and Nutrition.

• Chairperson & Non-Executive Director : Kiran Mazumdar Shaw
• Managing Director and CEO : Jonathan Hunt
• Founded : 1993
• Total Permanent Employee s: 2,685

11. Wockhardt

Wockhardt provides a reliable supply of medicines and vaccines across the world. Six New Chemical Entities (NCEs) have been developed under its novel antibiotics program.

7,000+ professionals across 27 nationalities worldwide help the company deliver world-class care services. They are among the top 4 companies in Cough Preparations. This company secures the #6 spot on the list of top biotech companies in India.

Apart from that, they actively participate in CSR activities. The Wockhardt Skills Development Institute trained 2400 students in FY 2019-20.

• Headquarters : Aurangabad, India
• Founder Chairman:  Habil Khorakiwala
• Founded : 1967
• Total Permanent Employee s: 5,106

12. Panacea Biotec

Panacea Biotec administered 10 billion+ doses for immunity against Polio in developing countries. This is arguably one of the best biotech companies in India. With a mission to innovate in support of life, their goal is to meet all healthcare needs with Panacea products.

The company recorded a turnover of Rs.1,404 million in the last financial year through its vaccine business. Panacea registered 440+ patents in their name and 110+ are under process.

• Headquarters : Punjab, India
• Chairman : Soshil Kumar Jain
• Founded : 1984
• Total Permanent Employee s: 849

13. Vivo Bio Tech Ltd.

Vivo Bio Tech Ltd . assists pharmaceutical & biotech companies in drug development & discovery.

They aim to build strategic global and regional partnerships to make high-quality healthcare consulting available to the market. Making significant headway in the commercialization of multiple products, they offer preclinical development services.

• Headquarters : Hyderabad, India
• WholeTime Director & CFO: K.T.V Kaladhar
• Whole Time Director: M Kalyan Ram
• Founded : 1987
• Total Permanent Employee s: 175

14. Serum Institute of India Pvt. Ltd. 

Serum Institute is one of the top biotech companies in India rapidly gaining market shares with its COVID-19 vaccine COVISHIELD . The organization’s state-of-the-art Vaccines Formulations Facility is helping them expand its global footprint.

They are transforming patient lives through the introduction of therapies that improve treatment outcomes while enhancing their health and well-being.

• Headquarters : Pune, India
• Chairman and Managing Director: Dr. Cyrus S. Poonawalla
• CEO: Mr. Adar C. Poonawalla
• Founded : 1966

15. Alpa Laboratories Ltd.

Alpha Labs manufactures capsules, gels, creams, ointments, ear and eye drops, injections, and tablets for human use.

Apart from that, it has products like Alpamin Bolus and Gentamicin Inj. BP Vet. for animals. They utilize differentiated technologies to transform healthcare and focus on the kind of innovation that binds affordability with accessibility.

• Headquarters : Indore, India
• Chairman : Mahendra Singh Chawla
• Founded : 1988
• Total Permanent Employees : 405

16. Camson Bio Technologies Ltd.

Camson Bio Technologies Ltd is an agriculture biotech company selling products in two segments namely Seeds & Vegetables and Agri Biotech Products.

To sell a wide range of goods, Camson blends conventional agricultural expertise with the latest developments in safety and security. These include non-poisonous, eco-friendly, and residue-free hybrid crops, bio-fertilizers, and biocides .

• Headquarters : Bangalore, India
• Managing Director/Compliance Officer : Dhirendra Kumar
• Total Permanent Employee s: 250

17. Genomic Valley Biotech Ltd.

Genomic Valley Biotech Ltd was previously called M/S Tushar Agribusiness Consortium India Ltd. It was built to conduct research in Biotechnology and produce Tissue Cultured Plants. Tissue culture utilizes small pieces of plant tissue which are cultivated in a nutrient medium.

• Headquarters : Haryana, India
• Non-Executive Director : Parul Agrawal
• Managing Director and CEO: Yogesh Agrawal
• Founded : 1994

18. Celestial Biolabs Limited.

Biotechnological products are the forte of Celestial Labs Limited . Some of their Proprietary products include Biovita, Rhumacel, Bioliv, and Cel-Digest.

They offer a wide range of Syrups, Capsules, and Granules to unlock value for stakeholders. As a part of CSR, they have adopted villages and districts in 6 states of India impacting more than a thousand lives as a part of this initiative.

• Managing Director : A N Singh
• Whole Time Executive Director & CEO : Amit Kumar Singh
• Founded : 1997

Other Biotech Companies in India

• ADINATH BIO-LABS LTD.
• Indian Immunologicals Limited
• Shantha Biotechnics Limited
• Genesis Ibrc India Ltd
• MAVENS BIOTECH LTD.
• SAAMYA BIOTECH (INDIA) LTD.
• Shree Ganesh Biotech (India) Ltd.

Final Thoughts on Best Biotech Companies in India

India is among the world’s top biotechnology destinations. Biotechnology research in India is largely financed by the public exchequer, unlike developed economies like the United States.

The above biotech companies in India are ranked based on the range of packaging products & films, annual income, market capital, orders taken in, and sales turnover.

Editorial Staff

[…] 15 Best Biotech Companies in India To Look Out For in 2021 […]

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Top 12 Emerging Biotech Companies in India

India is among the top 12 destinations for biotechnology worldwide. The Indian bioeconomy has grown from USD 62.5 billion in 2019 to USD 70.2 billion in 2020 at a growth rate of 12.3%. The Indian biotechnology industry is expected to reach USD 150 billion by 2025, with a CAGR (Compound Annual Growth Rate) of 16.4%.

The biotechnology industry in India comprises >2700 biotech startups and is estimated to reach 10,000 by 2024 which aims to provide high quality drugs, better diagnosis & MedTec products available at reasonable price.

Recently, India hosted the Biotech Startup expo 2022 which showcased around 300 biotech startups from various disciplines like biopharma, genomics, agriculture, and industrial biotech. 

Here are the top 12 emerging startups in India:

Pandorum Technologies

CEO and Co-founder -  Tuhin Bhowmick

Located in Bangalore, Karnataka, Pandorum Technologies is creating functional human tissues that can be used for medical research. Using 3D printing technology, the company is working on creating human liver tissue that can act as a replacement during liver transplantation or failures. 

XCode Life Sciences

CEO and Co-founder - Saleem Mohammed

Located in Chennai, Tamil Nadu, XCode Life Sciences develops testing kits that provide detailed information on nutrition, exercise, health, and ancestry. The company's personal genomics testing kits deliver reliable and useful genomic information aimed at improving human health and quality of life.

Oncostem Diagnostics

CEO & Founder:  Manjiri Bakre

Located in Bangalore, Karnataka, Oncostem Diagnostics creates predictive and prognostic tests intended to identify patterns of cancer recurrence risk.  The company's method entails combining the disease's molecular signature with clinicopathological criteria that have been used in the prognostic evaluation of cancer for years, allowing doctors to create the best treatment plans for their patients.

Zumutor Biologics

CEO and Co-founder -  Kavitha Iyer Rodrigues

Located in Bangalore, Karnataka, Zumutor Biologics aims to provide targeted NK cell therapies. The company creates high-diversity human antibody libraries to discover new immunotherapies and monoclonal antibodies, allowing doctors to access innovative immunotherapies that target innate immunity and modulate the tumor microenvironment.

Sea6 Energy

CSO and Co-founder -   Sri Sailaja Nori

Located in Bangalore, Karnataka, Sea6 Energy focuses on producing ethanol from seaweed and converting it into biofuel, plant growth stimulants, animal feed ingredients, and other renewable resources. This helps solve feedstock problems like land use, freshwater requirements, and opportunity costs. 

Vyome Therapeutics

CEO -  Venkat Nelabhotla

Located in New Delhi, Delhi, Vyome Therapeutics develops novel medicines and treatments for the treatment of inflammatory illnesses with locally active therapeutics. The company's novel medicines are identified and developed to treat refractory skin conditions such as persistent dskin fungal infections, resistant acne, and other skin bacterial infections using novel formulations for site-targeted applications.

Founder - Binay Panda

Located in Bangalore, Karnataka, Ganit Labs uses genomic sequencing to sequence and interpret data from various organisms. The company is government-funded and a non-profit organization. 

CEO -  Vedam Ramprasad

Located in Bangalore, Karnataka, MedGenome operates a genomics diagnostics and research platform to understand the genetic markers for metabolic disorders, cancer, and rare diseases. Using computing, analytics, and bioinformatics, the company can provide deep insights into these diseases on a molecular level.

Mapmygenome

CEO and Founder -  Anu Acharya

Located in Hyderabad, Andhra Pradesh Mapmygenome provides molecular diagnostics services. Based on these services, the company provides detailed genetic insights on drug responses, inherited conditions, and diseases.

Farcast Biosciences

CEO-  Mohit Malhotra

Located in Bangalore, Karnataka, Farcast Biosciences uses its innovative platform to preserve the tumor microenvironment. This enables doctors to evaluate the correct therapy that will be most beneficial to the patient before any treatment begins. 

Bugworks Research

CEO and Co-founder -  Anand Anandkumar 

Located in Bangalore, Karnataka, Bugworks Research develops novel antibiotic drugs to tackle problems associated with AMR (Antimicrobial Resistance). The company is also building small molecules against solid tumors, which can be used as both stand-alone and combined therapeutics. 

Bharat Biotech

Chairman & Managing Director -  Dr. Krishna Ella 

Located in Telangana, Hyderabad, Bharat Biotech develops biotherapeutics and vaccines that are safe and effective. Some of the products they have launched are REGEN-D to treat diabetic foot ulcers, a vaccine against typhoid called Typbar TCV® that received WHO-Prequalification in January 2018, and COVAXIN — a vaccine against Covid-19

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List of Top 6 Biotech Startups In India

Baishali Das Adhikari

In India, the biotechnology sector is a fast growing industries. The companies under these biotech startups are known for providing better diagnosis, high-quality drugs, and making medicines and MedTec products available at a reasonable price. They aim at getting the best outcome for developing health awareness and upgrading diagnosis facilities for betterment. With the developing technologies, the health care sector is also increasing their quality with the help of these startups in India.

Amid the pandemic, one of the industries that made a huge growth has to be the biotech industry without a doubt. Apart from the prescribed medication, people were also flocking to get in touch with daily vitamins and other possible nutrients too. This has enabled the biotech industry in India and all over the world take off and flourish. So, let's get to know what are these biotechnology startups in India in a little bit more detail.

Top 6 Biotech Startups in India

• Sea6 Energy
• Bharat Biotech
• Forus Health

Founded: 1978 Founder: Kiran Mazumdar Shaw Headquarter: Bengaluru

Founded in 1978, Biocon is one of the top biotech startups in India. It started  with a budget of INR 10,000 as a company that used to sell the enzyme papain. The focus of the company changed in the 1990s by the founder, Kiran Mazumdar-Shaw . To make a change, she decided to shift from selling enzymes to selling biopharmaceuticals. Gradually she got enlisted among the richest women in India.

The annual revenue of Biocon sums upto INR. 4,709 Crores in 2018. By 2020, they have also given access to more than 2.1 million patients through their biosimilars. As of now, their manufactured pharmaceutical ingredients are being sold in more than 120 countries throughout the world.

Founded: 2010 Founder: Nelson Vadassery, Sowmya Balendiran, Sailaja Nori, and Shrikumar suryanarayan Headquarter: Bangalore

This startup was launched as a way to come up with the solution to the problem of over-consumption of energy in India. Four IIT Madras graduates , Nelson Vadassery, Sailaja Nori, Sowmya Balendiran, and Sayash Kumar came forward with the help of their professor, Shrikumar Suryanarayan. Together, they founded the startup in 2010 and currently it is considered as a top biotech startup in India. The primary aim of the startup is to convert photosynthetic biomass, for instance, plants and algae to fuels - Something that will definitely come in handy in the near future!

It enables these elements to work into battling against the unending commercial use of energy. It is funded by the Department of Biotechnology and is incubated at the Centre for Cellular and Molecular Platforms (C-Camp). The startup incorporated a few patented techniques in order to facilitate the large-scale cultivation of selected sea plants. The Government of Karnataka has given to the company, the title of "Emerging Company of the Year" in the year 2012 .

Founded: 2013 Founder: Sam Santhosh Headquarter: Bangalore

Sam Santosh founded the startup, MedGenome, in 2013. It works at providing personalised genetic tests and medicines. It has its working genres scattered for a range of ailments, such as cancer, neurological ailments and diabetes. The largest next-gen sequencing lab in entire southeast Asia , MedGenome has its headquarter located in the USA as well as in bangalore, India.

The startup crossed a funding of  INR 192 crore in 2017. In the following year, 2018, it bagged the MedTech Breakthrough Award for Biomedical Research. It is leading globally in personalized medicine that provides unique genomic solutions. The areas of their conduct are mainly immuno-oncology, ophthalmology, diabetes, cardiology, and a few other rare diseases.

Founded: 1996 Founder: Krishna Ella Headquarter: Hyderabad

Bharat Biotech was founded in the year 1996. The Hyderabad based company was founded by an well known Indian scientist, Krishna Ella. In India, it is the very first pharmaceutical startup that has successfully developed a generic drug.

It has achieved a huge milestone globally as they developed and received the patent the vaccine Zikavac . This one has been formulated to fight the prevailing Zika virus. It has done indigenous work in developing the covid vaccine - Covaxin. The operating revenues of Bharat Biotech International Limited, generally range over INR 500 Crore.

Founded: 2010 Founder: Dr Vinay Panda and Dr Vijaya Chandru Headquarter: Bangalore

The Bangalore based startup , GANIT Labs, has been founded in the year 2010 by Dr Vinay Panda and Dr Vijaya Chandru. The abbreviation GANIT Labs stands for  Genomics Application and Information Technology Labs. As per the latest report on Zoominfo, the company has reached $3.8 million by 2019.

The primary aims of the company are to study genomes that are related to oral cancer. It also helps in mapping their respective genes. This company has been involved in manufacturing analytical equipment that will effectively analyse and manage genome data on a large scale. It is mainly from the genome sequencing of disease tissues such as cancer.

Founded: 2010 Founder: K. Chandrasekhar Headquarter: Bangalore

K. Chandrasekhar, the founder of Forus health, created the startup in 2010. The basic mantras of the company are being claimed as ‘Innovate’, ‘Implement’ and ‘Impact’. The company works to eliminate preventable blindness through an Ophthalmology device, which includes an intelligent pre-screening technique.

At present, the company operates in 14 other countries other than India. As of the financial year ending on 31 March 2019, operating revenues of Forus Health Private Limited has been displayed between INR 1 Crore - 100 Crore. However, as per the recent information given out by Zoominfo, the revenue has reached $5.7 million by 2020.

So with the growth of these biotechnology startups in India, the economy has also gotten a boost. As many of the above companies are actively participating in international transaction, the revenue can also possibly get a favourable development over the year. According to the reports, Indian BioEconomy is dwelling at around $33.6 billion. It has been predicted to grow in size upto $100 billion by 2025. With over 2,600 emerging biotech startups in India, our country has also included 50 BIRAC-supported incubators as well.

Which is the biggest biotechnology company in India?

Biocon Limited is the largest Biotechnology Company in India.

What is the best biotech company in India?

Some of the best biotechnology companies in India are:

Who is owner of Bharat Biotech?

Dr. Krishna Ella is the Chairman & Managing Director of Bharat Biotech International Limited.

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India Organic Biofach 2022

Gulfood dubai 2023, biotechnology, biotechnology industry in india, valued at us$ 92.3 billion in 2023, the indian biotechnology industry is targeted to reach us$ 150 billion by 2025 and us$ 300 billion by 2030., advantage india, skilled human capital.

* With a total population of 1.4 billion, 47% being under the age of 25, India has a large pool of young and skilled workforce.

* India has a large reservoir of scientific human resources including scientists and engineers.

* Biotechnology has emerged as a trending career option among the youth. According to a survey of Class 12th students in Delhi, Biotechnology was ranked as the preferred stream at No.4/5.

Government Support

* 9 DBT-supported biotech parks and 60 BIRAC-supported bio-incubators.

* In the Union Budget 2023-24, the Department of Biotechnology (DBT) was allotted Rs. 1,345 crore (US$ 162.7 million) to promote R&D.

* National Biopharma Mission is supporting 101 projects including more than 150 organizations and 30 MSMEs.

* The National Biotechnology Development Strategy 2020-25, provides the government with a platform to strengthen skill development, resource and innovation converging into one strong ecosystem for knowledge sharing.

* 100% under automatic route for greenfield projects for pharmaceuticals.

* While 74% is permitted under automatic route for brownfield projects, 100% under government route is permitted for brownfield investments.

* 100% under automatic route is allowed for the manufacturing of medical devices.

Epidemiological factors

* Patient pool expected to increase over 20% in the next 10 years, mainly due to rise in population.

* New diseases & lifestyle changes to boost demand for drugs and devices.

Panacea Biotec

Panacea Biotec was established in 1984 under the name Panacea Drugs Private Limited and got publicly listed in September 1995. The company does research and development, manufacturing, sales, distribution and marketing of pharmaceuticals, vaccines and biosimilars. The company’s portfolio includes prescription products in niche therapeutic areas such as pain management, diabetes & cardiovascular management, oncology, renal disease management, osteoporosis management, anti-tubercular, gastro-intestinal care products and vaccines.

Company Website

SERUM INSTITUTE OF INDIA

Serum Institute of India Pvt. Ltd. manufactures several vaccines, which include Polio, Diphtheria, Tetanus, Pertussis, Hib, BCG, r-Hepatitis B, Measles, Mumps and Rubella vaccines. 65% of children in the world are estimated to receive at least one vaccine manufactured by Serum Institute. Vaccines manufactured by the Serum Institute are accredited by the World Health Organization.

Biocon is fully integrated, innovation-led biopharmaceutical company, focussed on delivering affordable innovation. The company delivers innovative biopharmaceutical solutions.

Related News

India's Bioeconomy has increased 12 times in the past 10 years from US$ 10 billion in 2014 to US$ 120 billion currently, according to Dr. Jitendra Singh, Union Minister of State (Independent Charge) for Science and Technology, Personnel, Public Grievances, Pensions, Atomic Energy, and Space,.

Bharat Biotech, a vaccine and bio-therapeutics producer, and the University of Sydney Infectious Diseases Institute (Sydney ID) inked a Memorandum of Understanding (MoU) to collaborate on vaccine development and the global fight against infectious illnesses.

Union Minister Dr. Jitendra Singh said India will be among the top five global bio-manufacturing hubs by 2025. Biotech Startups have grown 100 times in the last 8 years from 52 odd startups in 2014 to 6,300+ presently.

An agreement was signed between THDC India Limited (THDCIL) and Indian Institute of Technology (IIT) Delhi to collaborate on research and development activities related to electric vehicle batteries, green hydrogen, geothermal technology, and waste management and recycling.

India has called for extended collaboration in biotech start-ups and vaccine development with a public-private partnership for global good.

BIOTECHNOLOGY CLUSTERS

• West Bengal
• Maharashtra

Industry Contacts

• Department of Biotechnology, Ministry of Science & Technology
• Department of Science and Technology, Ministry of Science and Technology
• Biotechnology Industry Research Assistance Council (BIRAC)
• Council of Scientific and Industrial Research (CSIR)
• Association of Biotechnology Led Enterprises (ABLE)
• The Biotech Research Society, India

List of Biotech Companies in India

The Indian biotechnology sector is expected to clock US$ 10 billion in revenue by 2015 on the back of emerging opportunities from around the world.

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Top 13 Biotech Companies in India 2022

Here we can see the List of Top Biotech Companies in India. India’s biotechnology sector has evolved steadily over the last two decades, placing the country among the top 12 biotechnology destinations in the world.

Top 10 Pharmaceuticals Companies in India

Biotechnology Companies

So here is the List of Biotechnology Companies in India which is arranged in alphabetical order.

• ADINATH BIO-LABS LTD.
• ALPA LABORATORIES LTD.
• BIOCON LTD.
• Camson Bio Technologies Ltd
• Celestial Biolabs Limited
• Genesis Ibrc India Ltd
• Genomic Valley Biotech Ltd
• MAVENS BIOTECH LTD.
• PANACEA BIOTEC LTD.
• SAAMYA BIOTECH (INDIA) LTD.
• Shree Ganesh Biotech (India) Ltd
• VIVO BIO TECH LTD.

List of Biotech Companies in India

So here is the list of Biotechnology Companies in India with company code and ISIN NO. The list of companies was arranged in the Alphabetical Order.

List of Pharma Company in India

Largest Biotechnology Company In India

Biocon Limited is the Largest Biotechnology Companies in India which has turnover of Rs 6315 Cr.

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1. biocon limited.

Biocon Limited (“Biocon” or “the Company”), is engaged in the manufacture of biotechnology products and research services.

• Revenue: Rs 6315 Cr
• Market Cap:   42,329  Cr.
• ROE:  12.86  %
• Sales Growth (3Yrs):  18.10  %

The Company is a public limited company incorporated and domiciled in India and has its registered in Bengaluru, Karnataka, India. The Company’s shares are listed on the Bombay Stock Exchange (BSE) and the National Stock Exchange (NSE) in India.

2. Serum Institute of India Pvt. Ltd

Serum Institute of India is ranked as India’s No. 1 biotechnology company, manufacturing highly specialized life saving biologicals like vaccines using cutting edge genetic and cell based technologies, antisera and other medical specialties.

Serum Institute of India Pvt. Ltd. is now the world’s largest vaccine manufacturer by number of doses produced and sold globally (more than 1.5 billion doses) which includes Polio vaccine as well as Diphtheria, Tetanus, Pertussis, Hib, BCG, r-Hepatitis B, Measles, Mumps and Rubella vaccines.

It is estimated that about 65% of the children in the world receive at least one vaccine manufactured by Serum Institute. Vaccines manufactured by the Serum Institute are accredited by the World Health Organization, Geneva and are being used in around 170 countries across the globe in their national immunization programs, saving millions of lives throughout the world.

• Revenue: Rs 5,900 Cr
• more than 1.5 billion doses
• 65% of the children in the world receive at least one vaccine manufactured by Serum Institute.

Serum Institute of India was founded in 1966 by Dr. Cyrus Poonawalla with the aim of manufacturing life-saving immuno-biologicals, which were in shortage in the country and imported at high prices. Thereafter, several life-saving biologicals were manufactured at prices affordable to the common man and in abundance, with the result that the country was made self-sufficient for Tetanus Anti-toxin and Anti-snake Venom serum, followed by DTP (Diphtheria, Tetanus and Pertussis) group of Vaccines and then later on MMR (Measles, Mumps and Rubella) group of vaccines.

The Philanthropic philosophy of the company still not only exists but has been proliferated to bring down the prices of newer vaccines such as Hepatitis-B vaccine, Combination vaccine etc., so that not only Indian’s, but the entire under-privileged children of the world are protected from birth onwards.

3. Panacea Biotec Ltd

Panacea Biotec is an Innovation driven Biotechnology company doing Research and Development, Manufacturing, Sales, Distribution and Marketing of Pharmaceuticals, Vaccines and Biosimilars.

Panacea Biotec was set up in the year 1984, under the name of Panacea Drugs Private  Limited with a commitment to make Innovative Products Affordable and Accessible to the masses. It got publically listed on Indian National Stock Exchanges in September 1995 as Panacea Biotec Ltd.

Panacea Biotec is witnessing a period of expansion across every aspect of our business from innovative products to customers in market, from manufacturing to regulatory approvals and thereby laying the foundation for translation of our vision in becoming greatest, largest and most admired biotechnology company in the World by 2020.

• Total Sales: Rs 544 Cr
• Market Cap: ₹ 1,165 Cr.
• ROCE: 1.30 %
• ROE: -67.6 %
• Face Value: ₹ 1.00
• Promoter holding : 73.6 %
• Debt to equity: 3.10
• Price to book value: 5.87
• EVEBITDA: 30.8
• Price to Sales: 2.14

Ardent Research and Development efforts have always been a great strength of Panacea Biotec. The main research areas are New Chemical Entities (NCE), New Biological Entities (NBE) Novel Drug Delivery System (NDDS) based pharmaceutical formulations, Novel peptides & human monoclonal antibodies and Vaccine development.

The company has developed four distinguished, ultra-modern, state-of-art R&D centres in different locations, having internal capabilities for constant research, with over 300 highly professional and skilled scientists engaged in various aspects of research. Focused research efforts have led to grant of worldwide product patents valid in over 68 countries for Panacea Biotec. As on 31st March 2011, the company had filed over 1400 patent applications in various parts of the world including India. Of these, 382 have been granted patent and others are under various stages of examination or publication by the patent authorities.

Some of these countries are USA, U.K., France, Germany, Italy, Sweden, Denmark, Spain, Finland, Switzerland, The Netherlands, New Zealand, Mexico, Brazil, Nigeria, Zimbabwe, Australia, South Africa, Japan, Russia, Canada, Ukraine, Korea, and China. The Company aspirations are supported by our Globally accredited USFDA approved manufacturing facility at Baddi supported by the 4 “State-of-the-Art” R&D Centres. The company has ultra-modern, state-of-art production facilities at Baddi (Himachal Pradesh), Lalru (Punjab) & Delhi for manufacturing tablets, capsules (including soft gelatin), ointments (including transgel formulation) liquids, herbal formulations and vaccines. The facilities are WHO cGMP compliant among other regulatory bodies such as USFDA, UKMHRA, Saudi FDA, ANVISA, etc. The product portfolio includes highly innovative prescription products in niche therapeutic areas such as Pain Management, Diabetes & Cardiovascular management, Oncology, Renal Disease management, Osteoporosis management, Anti-tubercular, Gastro-intestinal care products and Vaccines.

The Company current business stems from our leadership segments in India i.e. Transplant, Nephrology, Diabetes & Pain with some exclusive products based on patented Drug Delivery Systems.

First Nanotechnology based product ‘PacliAll’ (Paclitaxel in protein bound particles) was launched in 2011; it was the world’s first generic for Abraxane, manufactured by Celegene USA. Apart from fortifying our presence in the above segments; we are planning major forays in Gastrointestinal, Osteoporosis, Cardiovascular & more importantly Oncology.

Panacea Biotec is one of the largest Vaccine Manufacturing Company in India and is well acknowledged by the UN Health Agencies in partnering the Polio eradication initiative with supplies of millions of doses of WHO Pre-qualified Polio vaccine. As a sequel to the completion of full range of Oral polio vaccines (tOPV, mOPV1, mOPV3 & bOPV).

Panacea Biotec has introduced the next generation Inactivated Polio vaccine (eIPV) vide a collaboration with the Netherland Vaccine Institute (NVI). This vaccine has found extensive usage in India for more than 3 years now and is registered in Bangladesh. IPV is also in advanced stage of registration in 10 countries word wide with the target of being in more than 30 countries in a couple of years and has been put up for WHO prequalification which is expected soon.

Panacea Biotec is the first company in to have developed fully liquid Pentavalent vaccine (DTwP+Hep B+Hib) Easy Five in 2005. Easy Five is a WHO Prequalified vaccine being used in more than 25 countries worldwide.

The vaccines portfolio consists of Enivac-HB (Hepatitis B vaccine), Enivac-HB Safsy, Ecovac-4 (DTwP+Hep B), Easyfour (DTwP+Hib), which are also WHO prequalified. Vaccines in the offing are- Anthrax, Dengue, Japanese encephalitis and several others. A strong innovative vaccine pipeline is on the anvil which would pave the way for a consistent introduction of Next Generation Vaccines in future.

Panacea Biotec is the third largest biotechnology company (as per ABLE Survey, 2011), as well as among the top 50 pharmaceutical companies (as per ORG IMS March 2010) of India. To tap newer opportunities, Panacea Biotec has organized its formulation marketing into Six SBUs – PRO Care, Diacar Alpha, Diacar Delta, GROW Care, Onco Trust, and Critical Care, which enables it to respond to changes in the industry and marketplace. The Company has tied up with National Institute of Immunology, India for Japanese Encephalitis candidate vaccine, Biotech Consortium India Ltd. for the development, manufacture and marketing of Anthrax vaccine, worldwide and with National Institute of Health, USA, for use of a peptide-based product for generation of hair follicles and hair growth. Panacea Biotec has also collaborated with Netherlands Vaccine Institute for Inactivated Polio Vaccine; NRDC- India for Foot & Mouth Disease vaccine for veterinary use and Bio Farma-Indonesia for Measles vaccine. Panacea Biotec has established a countrywide sales and marketing network in India through a vibrant sales force of more than 1,500 professionally trained and highly motivated marketing and sales professionals and efficient logistic network of 22 sales depots/carrying and forwarding agents all over India to make its products available at all places and at all times. While Panacea Biotec Ltd has achieved a plethora of credentials on Home ground (India); it has also consolidated its presence in about 21 markets across CIS, Latin America, Middle East, Asia & Africa.

The Company International Pharma business performance for the current financial year is pegged at nearly US $ 16 million with a robust growth of nearly 150%. The financials are expected to improve in a similar exponential manner in the next 2-3 years due to expected commercialization in Key markets across US, Latin America & Europe. Panacea Biotec has identified brand building in exports as its thrust area and it has significant presence in the global markets including the CIS, Africa, the Middle East and Asia. The company is actively exploring opportunities for launching as well as licensing out some of our patented products for manufacture/marketing in developed countries in Europe & North America.

Raveendran R

Editor @ Indiancompaies.in

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Mr biocon company

Thank You Mandar..

Serum Institute of India PVT. LTD. is not listed which has around US$600 million turnover. Please include the same.

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Top 20 Most Promising Biotechnology Companies In India 2023

Top 20 Most Promising Biotechnology Companies In India 2023.

In this article today, we will take a look at the Top 20 Biotechnology Companies In India in 2023. 

India is one of the fastest-growing biotechnology markets in the world and is home to some of the leading biotechnology companies. These companies are involved in a range of activities including research and development, production, and commercialization of biotechnology products and services. In 2023, the top 20 biotechnology companies in India have continued to maintain their dominance and are at the forefront of the country’s biotechnology sector.

These companies are involved in various areas such as vaccines, biopharmaceuticals, medical devices , and more. They are not only serving the domestic market but also have a significant global presence. The biotechnology industry in India is growing at a rapid pace, and these companies are contributing to this growth by investing in research, innovation, and commercialization. These companies are playing a crucial role in transforming the healthcare landscape in India and around the world .

1.  Serum Institute Of India

The Serum Institute of India (SII) is one of the largest vaccine manufacturers in the world. It was founded in 1966 by Dr Cyrus Poonawalla and is headquartered in Pune, India. The company specializes in the production of life-saving vaccines and biological products, including vaccines for polio, diphtheria, tetanus, hepatitis B, and Haemophilus influenzae type B (Hib).

In recent years, SII has gained international recognition for its role in the COVID-19 pandemic. The company has been at the forefront of the global effort to develop and distribute vaccines against the virus and has partnered with several pharmaceutical companies, including AstraZeneca and Novavax , to manufacture and supply their vaccines to countries around the world.

In addition to its vaccine manufacturing activities, SII is also involved in research and development, as well as the production and distribution of a range of life-saving drugs and other medical products. The company is committed to providing affordable healthcare solutions to people around the world and has a strong reputation for quality and reliability in the pharmaceutical industry.

2. Panacea Biotech Ltd

Panacea Biotec is a leading pharmaceutical and biotechnology company based in India. It was founded in 1984 and has its headquarters in New Delhi. The company specializes in the development, manufacturing, and marketing of a wide range of pharmaceutical products, including vaccines, antibiotics, and anti-retroviral drugs.

Panacea Biotec has a strong presence in the Indian market and is also well-established in international markets, including the United States, Europe, and Africa. The company has a state-of-the-art research and development facility and is committed to investing in new technology and innovative product development to meet the changing needs of the pharmaceutical industry.

In addition to its pharmaceutical business, Panacea Biotec is also involved in the development and production of biotech-based products , including biotech crop protection products, diagnostic kits, and animal health products. The company has a strong commitment to quality and is accredited by several international regulatory agencies, including the US Food and Drug Administration (FDA) and the European Medicines Agency (EMA).

Baxter India is a subsidiary of Baxter International Inc., a global medical products and services company that was founded in 1931 and is headquartered in Deerfield, Illinois, USA. The company provides a wide range of products and services to healthcare providers and patients around the world, with a focus on increasing access to healthcare and improving patient outcomes.

Baxter India is based in Mumbai, Ahmedabad, and Gurgaon India, and provides a range of products and services to healthcare providers and patients in the region, including medical devices, pharmaceuticals, and renal care products. The company’s product portfolio includes a range of innovative solutions for a variety of medical applications, including intravenous (IV) solutions, infusion pumps, dialysis products, and other products for the treatment of various medical conditions.

In addition to its commercial activities, Baxter India is also involved in a range of initiatives aimed at improving access to healthcare and promoting medical education and research . The company has a strong commitment to sustainability and corporate responsibility and is involved in some initiatives to reduce its environmental impact and promote social responsibility.

Biocon Limited is an Indian biopharmaceutical company based in Bangalore. Founded in 1978, the company has established itself as one of the leading biotechnology companies in India and is recognized globally for its expertise in the development and production of innovative biopharmaceutical products.

Biocon’s portfolio includes a range of biologic drugs and therapies, including biosimilars, insulins, and immunotherapy products, as well as a range of research-based contract research and manufacturing services. The company has a strong research and development focus and has made significant investments in its research and development capabilities to drive innovation and growth in its core businesses.

In recent years, Biocon has gained recognition for its role in the global fight against COVID-19  and has partnered with several international pharmaceutical companies to develop and manufacture vaccines and therapies for the disease. The company is also involved in several initiatives aimed at improving access to affordable healthcare in developing countries and has a strong commitment to social and environmental sustainability.

6. SIRO Clinpharm

SIRO Clinpharm is a leading clinical research organization (CRO) based in India. The company provides a range of clinical trial services, including clinical trial management, data management, biostatistics, and regulatory support, to pharmaceutical and biotechnology companies worldwide.

Founded in 2002, SIRO Clinpharm has established a reputation as a reliable and efficient provider of high-quality clinical research services and has extensive experience in conducting clinical trials across a range of therapeutic areas, including oncology, infectious diseases, and cardiovascular diseases.

The company has a strong commitment to ethical clinical research practices and is fully compliant with international regulatory standards, including those set by the US Food and Drug Administration (FDA) and the European Medicines Agency (EMA) . SIRO Clinpharm has a large network of experienced clinical research professionals and state-of-the-art technology and infrastructure to support its clinical trial activities.

7. Syngene International Ltd.

Syngene International is a leading global contract research organization (CRO) based in India. The company provides a range of research and development services, including custom synthesis, process research and development, analytical development, and clinical trial support, to pharmaceutical, biotech, and agribiotech companies worldwide.

Founded in 1993, Syngene has a strong reputation for delivering high-quality research services and has extensive experience in the development of small molecule and biological drugs . The company has a large network of experienced scientists and state-of-the-art research facilities and technology to support its research and development activities.

In addition to its research services, Syngene also provides a range of laboratory services, including analytical testing and custom synthesis , and is fully compliant with international regulatory standards, including those set by the US Food and Drug Administration (FDA) and the European Medicines Agency (EMA).

With a focus on innovation and quality, Syngene has established itself as a leading contract research organization in India and is well-positioned to continue its growth and expansion in the global market for research and development services.

8.  Shantha Biotech

Shantha Biotechnics is a leading Indian biopharmaceutical company based in Hyderabad. The company was established in 1993 and is focused on the development, production, and marketing of biopharmaceutical products, including vaccines, immunoglobulins, and other biologics.

Shantha Biotechnics has a strong presence in the Indian market and is well-established in international markets, including Asia, Africa, and the Middle East. The company has a state-of-the-art research and development facility and is committed to investing in new technology and innovative product development to meet the changing needs of the biopharmaceutical industry .

One of the key strengths of Shantha Biotechnics is its expertise in the development and production of vaccines, and the company has been involved in several large-scale vaccine development and manufacturing initiatives in India and internationally.

With a strong commitment to quality and social responsibility, Shantha Biotechnics is well-positioned to continue its growth and expansion as a leading biopharmaceutical company, both in India and globally. 

9. Novo Nordisk

Novo Nordisk is a Danish multinational pharmaceutical company specializing in the research, development, and production of drugs for the treatment of chronic diseases, including diabetes, obesity, and haemophilia. The company was founded in 1923 and is headquartered in Bagsvaerd, Denmark.

Novo Nordisk is one of the world’s largest producers of insulin and is recognized as a leader in the development and production of innovative treatments for diabetes. The company’s product portfolio also includes drugs for the treatment of obesity, growth hormone deficiency, and haemophilia.

In addition to its pharmaceutical products, Novo Nordisk is also involved in a range of initiatives aimed at improving access to healthcare for people with chronic diseases, particularly in developing countries. The company has a strong commitment to sustainability and corporate responsibility and is involved in several initiatives to reduce its environmental impact and promote social responsibility.

With a strong presence in Europe, North America, and Asia, Novo Nordisk is well-positioned to continue its growth and expansion as a leading pharmaceutical company and a key player in the global fight against chronic diseases .

10.  Novozymes South Asia

Novozymes South Asia is a subsidiary of Novozymes, a Danish biotechnology company that specializes in the development and production of enzymes and microorganisms for a wide range of industries, including agriculture, food and beverage, textiles, and bioenergy.

Novozymes South Asia is based in India and serves as the company’s regional hub for the South Asian market. The company offers a range of innovative biotechnology solutions for a variety of industries and applications, including enzymes for improving the efficiency of bioenergy production, enzymes for the food and beverage industry, and biopesticides for agriculture.

In addition to its commercial activities, Novozymes South Asia is also involved in a range of sustainability initiatives aimed at promoting the responsible use of natural resources and reducing the environmental impact of its operations. The company is committed to sustainability and works closely with its customers to develop innovative biotechnology solutions that support a more sustainable future .

11. Wockhardt Ltd.

Wockhardt Limited is an Indian multinational pharmaceutical and biotechnology company based in Mumbai, India. The company was founded in the 1960s and is engaged in the research, development, production, and marketing of a wide range of pharmaceutical products and biopharmaceuticals.

Wockhardt’s product portfolio includes a wide range of prescription and over-the-counter drugs, as well as biopharmaceuticals, including vaccines, enzymes, and other biological products. The company is also involved in the production of active pharmaceutical ingredients (APIs) and has a strong presence in the international market, with a particular focus on emerging markets in Asia, Africa, and South America.

In addition to its pharmaceutical and biopharmaceutical activities, Wockhardt is also involved in a range of initiatives aimed at promoting healthcare and improving access to essential medicines, particularly in developing countries. The company has a strong commitment to sustainability and corporate responsibility and is involved in many initiatives to reduce its environmental impact and promote social responsibility.

12. Ajanta Pharma and Biotech

Ajanta Biotech is a leading Indian pharmaceutical and biotechnology company that specializes in the research, development, and production of generic and biosimilar drugs. The company is based in Mumbai and was established in 2006.

Ajanta Biotech is focused on delivering high-quality, affordable medicines to patients and healthcare providers in India and around the world. The company’s product portfolio includes a range of generic drugs and biosimilars, including treatments for cancer, autoimmune diseases, and other chronic conditions.

In addition to its pharmaceutical activities, Ajanta Biotech is also involved in a range of initiatives aimed at improving access to healthcare and promoting medical education and research. The company has a strong commitment to sustainability and corporate responsibility and is involved in some initiatives to reduce its environmental impact and promote social responsibility.

13.  Bioclinica

Bioclinica is a global provider of clinical trial services to the pharmaceutical, biotechnology, and medical device industries. The company was founded in 1989 and is headquartered in Princeton, New Jersey, with additional offices and locations around the world.

Bioclinica offers a range of clinical trial services, including clinical trial management, imaging services, electronic data capture, clinical trial supplies, and site management services. The company’s services are designed to help its clients bring their products to market more efficiently and effectively while ensuring the highest standards of patient safety and data quality.

Bioclinica is committed to advancing the science of clinical trials and is involved in a range of initiatives aimed at improving the efficiency and effectiveness of clinical trials, while also promoting patient safety and data quality . The company is also committed to sustainability and corporate responsibility and is involved in several initiatives to reduce its environmental impact and promote social responsibility.

14. Indian Immunologicals

Indian Immunologicals Limited (IIL) is an Indian biotechnology company that specializes in the research, development, production, and marketing of a wide range of biological products, including vaccines, immunoglobulins, and other biologicals. The company was established in 1982 and is based in Hyderabad, India.

IIL’s product portfolio includes a range of vaccines and immunoglobulins for the prevention and treatment of a variety of medical conditions, including bacterial and viral infections, autoimmune diseases, and other conditions. The company is also involved in the research and development of new biological products, with a focus on innovative and sustainable solutions for global healthcare challenges.

In addition to its commercial activities, IIL is also involved in a range of initiatives aimed at improving access to healthcare and promoting medical education and research. The company has a strong commitment to sustainability and corporate responsibility and is involved in many initiatives to reduce its environmental impact and promote social responsibility.

15.  Windlas Biotech Private Limited Dehradun

Windlas Biotech Private Limited is a pharmaceutical company based in Dehradun, Uttarakhand, India. The company focuses on the research, development, production, and marketing of pharmaceutical and herbal products. The company’s product portfolio includes a range of pharmaceutical products, herbal supplements, and other health-related products, aimed at improving the health and well-being of patients and consumers.

Windlas Biotech is known for its focus on quality and sustainability, with a strong commitment to responsible manufacturing and environmental stewardship. The company is involved in some initiatives to promote medical education and research and to support the local communities in which it operates.

As a growing company, Windlas Biotech is well-positioned to continue its expansion and growth, serving the needs of patients and consumers around the world. However, specific details about the company’s operations, financial performance, or product portfolio may not be readily available, as Windlas Biotech is a private company . For more information, it is best to contact the company directly.

16. Virchow Biotech

Virchow Biotech is a biotechnology company based in India. Virchow Biotech’s product portfolio includes a range of vaccines and immunoglobulins for the prevention and treatment of a variety of medical conditions, including bacterial and viral infections, autoimmune diseases, and other conditions. The company is also involved in the research and development of new biological products, with a focus on innovative and sustainable solutions for global healthcare challenges.

In addition to its commercial activities, Virchow Biotech is also involved in a range of initiatives aimed at improving access to healthcare and promoting medical education and research. The company has a strong commitment to sustainability and corporate responsibility and is involved in several initiatives to reduce its environmental impact and promote social responsibility.

With a strong presence in India and a growing international presence, Virchow Biotech is well-positioned to continue its growth and expansion as a leading provider of biological products , serving the needs of patients and healthcare providers around the world. However, specific details about the company’s operations, financial performance, or product portfolio may not be readily available, as information about the company may be limited.

17.  Cryoviva Biotech and Life Sciences

Cryoviva Biotech and Life Sciences is an Indian biotechnology company specializing in the field of regenerative medicine and life sciences. The company provides a range of products and services related to the preservation of umbilical cord blood and tissue, including cord blood banking, tissue banking, and cellular therapy.

Cryoviva Biotech and Life Sciences are focused on improving access to regenerative medicine and life sciences, with a mission to make the benefits of these technologies available to people around the world. The company is committed to the highest standards of quality and safety in all of its products and services and is continuously working to advance the science of regenerative medicine and life sciences through research and development.

With a strong presence in India and a growing international presence, Cryoviva Biotech and Life Sciences are well-positioned to continue its growth and expansion as a leading provider of regenerative medicine and life sciences products and services. However, specific details about the company’s operations, financial performance, or product portfolio may not be readily available, as information about the company may be limited.

18. British Biologicals Bengaluru, Karnataka

British Biologicals is a biotechnology company based in Bengaluru, Karnataka, India. The company specializes in the research, development, production, and marketing of a range of nutritional and health supplements, including vitamins, minerals, and other nutrients.

British Biologicals is committed to improving the health and well-being of people around the world through its range of high-quality, science-based products. The company uses cutting-edge research and advanced technology to develop innovative and effective products that meet the diverse needs of its customers.

With a strong presence in India and a growing international presence, British Biologicals is well-positioned to continue its growth and expansion as a leading provider of nutritional and health supplements . However, specific details about the company’s operations, financial performance, or product portfolio may not be readily available, as information about the company may be limited.

19. The Council of Scientific & Industrial Research (CSIR)

The Council of Scientific & Industrial Research (CSIR) is an autonomous research organization in India. It was established in 1942 and is one of the largest and oldest publicly funded research and development organizations in the country. CSIR is headquartered in Delhi and has a network of 39 national laboratories and research institutes across India.

CSIR conducts research in a wide range of scientific and industrial fields, including biotechnology, chemical sciences, engineering, earth sciences, environmental sciences, food and agriculture, health sciences, information technology, materials sciences, and mathematical sciences. The organization is involved in basic and applied research, and its scientists work to develop new technologies and products that address important national and global challenges.

CSIR plays an important role in promoting scientific and industrial research in India and is recognized as a leading research organization in the country. The organization has a long history of scientific excellence and innovation  and continues to make significant contributions to the advancement of science and technology in India and around the world. 

20. Lee Pharma Hyderabad

Lee Pharma is a pharmaceutical company based in Hyderabad, India. The company was founded in 1993 and specializes in the manufacturing and marketing of a range of pharmaceutical products, including prescription drugs, generic medicines, and over-the-counter products.

Lee Pharma has a wide product portfolio that covers various therapeutic areas, including the cardiovascular, central nervous system, gastrointestinal, and respiratory disorders, among others. The company also offers a range of contract manufacturing services, including the production of active pharmaceutical ingredients (APIs) , intermediates, and finished formulations.

Lee Pharma has a strong focus on quality and is committed to meeting the highest standards of product quality and safety. The company is accredited with several certifications, including ISO 9001:2015 and WHO-GMP , and is committed to continuous improvement and innovation in its manufacturing processes and product offerings.

India has a thriving biotechnology sector, with a large number of companies operating in the field of life sciences and biomedicine. These companies are involved in a wide range of activities, including research and development, production and marketing of pharmaceuticals, vaccines, and nutritional supplements.

These companies are playing a critical role in addressing some of the most pressing challenges in human health and well-being, including infectious diseases, cancer, and malnutrition. They are also contributing to the development of the biotechnology sector in India, by investing in research, promoting innovation, and creating new products and technologies. With a supportive policy environment and a growing pool of skilled professionals, the biotechnology sector in India is poised for continued growth and success in the years to come.

Vanshika Gangrade

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• v.152(4); 2020 Oct

Translational research in biomedical sciences in India: Challenges, observations & national perspectives

Rahmat bano.

Innovation & Translation Research Cell, Indian Council of Medical Research, New Delhi 110 029, India

Sushma Gupta

Chander shekhar.

Translational research (TR) signifies a multidisciplinary approach to expedite availability and development of clinically relevant affordable products and new strategies for improving the existing healthcare system. It encompasses new discoveries, innovations, technologies and medical devices, on one hand, and policy-based research, on the other, so as to address the medical problem/issues more effectively 1 . Scientific communities of various countries define TR as per their own local needs and socio-economic scenario. The broad vision and goal of TR is to connect different stakeholders and thus promote 'bench-to-bedside and bedside-to-community' research with the principal aim of addressing a clinical problem more effectively. The mission of TR is to hasten the processes involved in new discovery and innovations with the ultimate benefit to the community 2 , 3 . Accordingly, the primary aim is to facilitate the mission and vision of TR by bringing all interdisciplinary stakeholders on a common platform and introducing new products/technologies into the market and medical advancements in a cost-efficient manner for social benefits 4 .

All funding agencies and regulatory bodies worldwide are focusing on three main agendas of TR: ( i ) identifying basic research information or new innovation having TR potential, ( ii ) expedite grant approvals within the ethical prevue and patents in judicial boundaries, and ( iii ) speedy availability of these medical therapies or technologies to the community. As a result, health policies are being reformed at the government level, while workforce training and development are being initiated at various levels and awareness programmes at academia and industry levels 5 . However, the legal and governance framework needs greater refinements to expedite the need of healthcare system.

Multidisciplinary stakeholders including appropriate faculty, institutions, industry regulators and policymakers, both at the national and international levels, are needed to achieve more translational leads and innovations. Currently, revolutionary advancements in biomedical research using gene- and cell-based therapy, nanotechnology, proteomics, genomics, artificial intelligence and robotic technologies are redefining the research strategies. Therefore, there is a need to redefine traditional research strategies from fundamental basic research to clinical applications to lead new technologies and therapeutics 5 .

Understanding early phase of TR means that other groups can reproduce the research component, with validation by a third party, while the Intellectual Property Rights (IPR) remains with the innovator. Effective TR approaches are needed to develop process of proof of concept, to file patent and to validate prototype. Further, the research leads may reach the market more faster thorough technology transfer and commercialization. Hence, an integrated approach is required to support innovation from basic research to the delivery of potential public healthcare products 6 , 7 .

This article is an effort to identify the checkpoints and bottlenecks of TR and possible perspectives to redefine concrete strategies that protect and improve human health. As Indian scientists are well on the way to adopt translational biotechnologies including translational engineering, it is time to harmonize TR in biomedical sciences and redesign TR strategies with new innovations, therapeutic modalities and clinical research (CR) programmes for public health policies.

International scenario - translational research initiatives

To deal with the challenges of TR, various guidelines/models/regulatory amendments are being formulated to ease the innovative methods and technologies and thus fast track their outreach to the community. National Institutes of Health (NIH), United States, is following disease-oriented drug-targeted strategies for TR 8 . The Centre for Drug Evaluation and Research, United States-Food and Drug Administration (US-FDA) has established a separate cell, namely 'Office of Translational Sciences', to catalyze and provide thrust to the basic researchers for technology transfer, drug regulatory review process, and all other facilities to expedite TR 9 . US-FDA is also facilitating accelerated approvals for drug-targeted therapies, especially for cancer and for breakthrough therapies 10 . The UK has also developed one of the remarkable Translational Medicine (TM) systems in the European Union. The Medical Research Council targets fundamental discoveries from basic research and works with multidisciplinary experts. The SPARK programme of British Council, an initiative for partnership between university and industry experts, has been established to provide a cost-effective model to generate proof of concept using industrial standards 11 , 12 . Two types of biomedical research centres (BRCs) have been developed in the UK, which are playing critical roles for advancement of TR, i.e . Comprehensive BRCs and Specialist BRCs 13 . Another initiative 'Translation Together' is to link the gap of new innovations between basic fundamental discoveries related to human disease and the delivery of new therapeutic options to the patients. The efforts are collectively been initiated among LifeArc in the UK, the European Infrastructure for TM in the European Union, The Centre for Drug Research and Development in Canada, Therapeutic Innovation, Australia, and the NIH's National Center for Advancing Translational Sciences in the US 14 . For Indian research setup, the SPARK model would be the most suitable model. This model includes more than 100 experts drawn from different scientific fields, social areas and various industrial subject matter experts (SMEs) work together as per the project basis. They focus more on fundamental research for drug discovery and development process.

Translational research initiatives in India

To combat with global conundrum of TR, certain initiatives have been taken by various scientific and biomedical funding agencies of the Government of India (GoI). Some initiatives on TR by the Indian organizations are narrated below.

The Department of Biotechnology (DBT), Ministry of Science and Technology (MoST), GoI, took an initiative to establish an autonomous institution named Translational Health Science and Technology Institute in 2010. Initially, the aim of this institution was to promote fundamental research with multidisciplinary approach. The focus was on translating the identified leads to scientific and technological prototypes, and to promote innovations and patents by transforming the scientific leads for improvement in healthcare system. The ultimate objective is to develop new strategies for diagnosis and management of diseases. These programmes will help in creation of an inter-institutional ecosystem in the Biotech Science Cluster, focussed on the development of an academia-biotech-industry collaboration within major innovation hubs 15 .

The Biotechnology Industry Research Assistance Council (BIRAC) is a not-for-profit Public Sector enterprise, set up by the DBT, MoST, GoI. The initiative of BIRAC is mainly focussed to encourage and empower the emerging biotech industries in the Indian continent. The modus operandi is still being developed for funding; focusing more on targeted funding, IP management, technology transfer and partnership schemes that help bring innovation excellence to Indian biotech firms and strengthens them to get global recognition 16 . BIRAC has provided financial and mentoring support to more than 500 companies and nearly 500 young entrepreneurs or start-ups. BIRAC has initiated partnerships with several national and global network including more than 15 implementing agencies. In addition, nearly 700 national experts from academia, industry, public and private research laboratories, donor agencies and other government departments have been working hand in hand to contribute towards building the innovation ecosystem of India 16 .

Standford India Biodesign (SIB) programme started in 2007 and continued till 2014. SIB is an innovation programme implemented by DBT, MoST, All India Institute of Medical Sciences (AIIMS), New Delhi, and Indian Institute of Technology, Delhi (IITD), in collaboration with Queensland University of Technology, Australia, and Hiroshima University, Japan. For implementation of the programme, the DBT has engaged Biotechnology Consortium of India Limited to manage the techno-legal activities of this programme. The mandate of this programme is to train next generation of medical technology innovators in India. The focus is on invention/innovation and early-stage development of affordable, accessible and available medical technologies for Indian population 17 . During the last decade since inception, this interdisciplinary programme has plotted some landmark achievements; it has trained more than 100 medical technology innovators (doctors, engineers, designers, juvenile entrepreneurs); more than 50 prototypes have been developed so far which have been further refined and validated internationally and tested [both preclinical and clinical trials (CTs)]; more than 50 medical devices developed by young innovators from IITD and faculty of AIIMS got patented; 15 technologies have been transferred and nine medical technology have been sync with the Start-up India programme 17 .

Apart from basic biomedical research, the Central Drug Standard Control Organization (CDSCO), India, is also trying to reform rules for approval of investigational new drugs, innovations, new interventions, CTs and new medical devices as per the current requirements 18 . The multinational companies are introducing their medical devices by tailoring their product portfolio as per the Indian market needs to reduce out-of-pocket expenditure for patients 18 .

Observations of translational research leads: Redefining funding policies

India, being a signatory of United Nations Mission for Sustainable Development Goals till 2030 4 , is actively participating to improve health research in the country on macro and micro levels. Under the Ministry of Health and Family Welfare, the Department of Health Research (DHR) has initiated many programmes including Standard Treatment Workflow (STW) and Health Technology Assessment (HTA) in India as a part of TR to evaluate new cost-effective health technologies and medical devices which can be included in the National Health Programmes 4 . The Indian Council of Medical Research (ICMR), New Delhi, initiated TR programme under DHR in 2008.

Run on to identify potential translational leads emerging from research done in yester years, the ICMR constituted expert committee to screen the intramural completed project reports to identify any potential lead for further research. During these programmes, diagnostic kits for various diseases and vaccines were developed. Till date, 23 technologies have been transferred to the industry, of which four have been commercialized and 19 are in pipeline for commercialization ( https://main.icmr.nic.in/technology ). Later, in 2017, similar screening was initiated for extramural projects to identify translational potential, if any in the completed project reports of all technical divisions of the Council, viz . Non-communicable Diseases, Epidemiology and Communicable Diseases, Reproductive Biology and Child Health, Nutrition, Bioinformatics and Basic Medical Sciences.

The project reports from basic medical sciences were exploratory, observational and experimental. Although these were reasonably good research projects, the translation component was missing in them. A few of these were comparative studies involving both basic and clinical sciences. These were well started up to T0 level (discovery stage, in silico , in vitro ) and T1 level (animal studies) of translation. Although the data emerging from these reports were informative, most lacked proof of concept and a large majority required proper study design. The observed outcome could not reach up to Phase III in clinical randomized control trial; hence, no proof of concept or potential translational value could be observed. Only a few projects reached at T2 level ( i.e . development of product/patent/proof of concept/prototype development/validation level). A more in-depth planning could have helped to achieve the goals particularly from wet laboratory (experimental studies) or any clinical laboratory set-ups.

Some encouraging findings in various forms of successful translation were observed in the preview of funding agency. Around 3.2 per cent reports reflected translation in various forms of basic research and clinical findings, being used successfully by other researchers, doctors or public on various portals (development of various registries). Some findings have been submitted to the Ministry of Health (State and national levels) for policy and guidelines formulations.

Challenges in translational research from basic research to product development

The TR is not just a linear process; it can be interconnected with translational bridges between disciplines. While there are many hurdles at every stage of development, the challenges in translating include: ( i ) basic non-CR to new innovation/product and diagnostic or prognostic biomarker assays, ( ii ) new drug development and interventions, ( iii ) CR to develop new therapeutic modalities, ( iv ) evidence-based open-minded community studies to add and develop healthcare policies/programmes, and ( v ) formulating new guidelines for disease prevention by policymakers. The major bottlenecks identified are slow regulatory approvals, slow patent updates and expensive patents on high revenue products, less community support, untrained workforce, inadequate research funding support and increasing competitions with other companies (indigenous as well as foreign importers) 19 , 20 . The major gaps from basic research to CR and innovations to reach market for healthcare system are discussed below 5 , 6 , 7 , 19 , 20 ( Fig. 1 ).

Gaps between basic and translational research. Source : Refs 5 , 6 , 7 , 19 , 20 .

Gaps between basic translational research to clinical research (CR)

Immediate need is to redefine the linear drug development processes used in life-threatening diseases, viz. cancer, infectious diseases such as HIV and vaccines. The following considerations may lead us to achieve our goals: ( i ) innovative medical devices with established proof of concept in pilot study regulators need to be facilitated with faster approval process 2 . ( ii ) For these trials, the difference between exploratory and confirmatory CTs can be practiced rather than sticking to the traditional expensive and cumbersome Phase I-IV studies. This can be achieved by conducting CTs with the freedom of conducting ethically approved and clinically proved efficacy and safety, and/or proof of concept in a viable number of patients with appropriately adopted randomizations 7 . ( iii ) Confirmatory CTs need to be less expensive as compared to the classical ways of regulatory approvals of these trials. To achieve this, collaborative set-up should be encouraged to conduct CR in various platforms having expertise in specific components and data collection. There is also a need for early controlled access to patients once the confirmatory trial reaches interim conclusions or results 7 . ( iv ) Pharmacovigilance is required and pharmaco-economics need to be well analyzed before wide-access and long-term re-embracement policies 21 . ( v ) Identifying new gold standards for diagnostic and treatment approach for TR with proper and viable validations 21 . ( vi ) Validation of clinically proven and most feasible biomarkers with standardized procedures needs to be adopted before technology transfer 22 . ( vii ) Risk-benefit appraisals need to be improved with a relook into the cost-effective research set-up. ( viii ) Drug patent facilities of Indian Pharmaceutical Industries should fasten the process 23 . ( ix ) Quicker third party validation for life-threatening drugs needs to be dealt by an independent cell with fast-track approvals 23 .

Translational research gaps in institutional set-up: Road map

After screening more than 1000 project reports, the following points were emerged: ( i ) the study design needs to be much focussed to address outcome in terms of leads/translational value or transformation of any developed prototype. However, it should not be simply observational, experimental or exploratory study, ( ii ) statistical evaluations need to be appropriate as per the study design and it should be possible to draw valuable meaning from the outcome, ( iii ) infrastructure needs to be updated/upgraded from the older techniques used by principal investigators (PIs) to obtain faster and accurate results. Re-engineering of the research environment is needed, ( iv ) one of the important challenges is validation of research outcome which is not in regular practice by the researchers. Validation may be in-house within the same institution or same organization by different group (first party) or second party in National Accreditation Board for Testing and Calibration Laboratories. It was noted that the PIs were not aware about the process of validation of the data or prototype of their research outcome. Awareness programmes from funding agencies can help to deal this challenge, ( v ) the concept of commercialization and technology transfer needs to be inculcated in the PIs. For this, the funding agency can play an important role of effective catalyst, ( vi ) expenditure on obtaining patent for any lead from basic research and developed prototype must be borne by the funding agency to promote more patents applications, ( vii ) initiatives need to be taken by the PIs towards confirming basic research findings and develop leads into clinical efficacy and foster research collaboration with clinicians in hospitals and clinical institutions. Funding agency can also facilitate such a collaboration with own or other relevant institutions, ( viii ) while the PI is required to take initiatives for FDA filings for their research findings to commercialize or market their product, the funding agency must support and facilitate these initiatives, ( ix ) the PIs need to upgrade knowledge through educational and training opportunities provided by the funding agencies and/or develop industrial collaboration to scale-up the product at low costs, and ( x ) integrated research network needs to be developed within the institution or intra-institution set-ups. Serious thinking is needed to deal with the identified barriers for successful implementation of TR and TM, so that the affordable therapies can reach the community.

Perspectives: Policy consideration to accelerate translational research in India

The biomedical funding organizations in India need to improve the fundamental or basic research infrastructure before approval of biomedical project. A strong coordination is required within the stakeholders to achieve the specific outcome in a predefined framework when planned for goal-oriented TR projects. In addition, new innovation models are required to work for discovery through validation which includes translational management team (TMT) to facilitate deliverables 24 . The TMT may facilitate validation of leads ( i ) from animal studies, CTs and biotech research by having collaboration/outsource with multidisciplinary team with Good Manufacturing Practices for animal testing or biotech innovations, ( ii ) Good Clinical Practices compliance in hospital set-ups or medical research institutions or CT management, and ( iii ) facilitate through validation consortium. For example, recently, many Pharma companies including Pfizer (on bio-therapeutic discoveries and development), Johnson and Johnson (on schizophrenia drug development), and AstraZeneca (on stem cell collaborations) have developed the innovation models and working on their developed model system 24 , 25 . In Figure 2 , a few considerations are highlighted to accelerate TR in India 7 , 12 , 20 , 21 , 22 , 23 , 24 , 25 .

Translational research perspectives in India: In view of different stakeholders. PIs, principle investigators; SMEs, subject matter experts; SOPs, standard operating procedures. Source : Refs 7 , 12 , 20 , 21 , 22 , 23 , 24 , 25 .

Biomedical as well as clinical research and development require a shift with an integrated approach from researchers and clinicians to initiate innovative ideas and discoveries which can fulfill the need driven requirements of the patients. The fundamental basic research needs to be evidence based, can be validated and target oriented which will facilitate identification of potential leads for translational discoveries. The funding agencies need initiatives to deal with the TR conundrum by redefining their policies, strategies and formulate the guidelines to support fundamental research by bridging the translational gaps. Regulatory reforms are essential to facilitate early approvals for ongoing new drug discoveries and CR. Restructuring and modifications in patent laws are required to hasten up the process of translational research which may facilitate the innovations and primary health technologies to hit market in affordable rates. There is a need to conceptualize TR programs with close collaboration within all stakeholders on an open exchange ongoing forum.

Acknowledgment:

Authors thank for language editing to Dr N.K. Mehra, Former Dean Research, All India Institute of Medical Sciences (AIIMS), New Delhi, currently holds the ICMR Dr C.G. Pandit National Chair at AIIMS, New Delhi.

Conflicts of Interest : None.

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Indian Hotels Company Achieves 300-Hotel Milestone Two Years Ahead of Schedule

Bulbul Dhawan , Skift

April 3rd, 2024 at 12:17 PM EDT

IHCL witnessed record number of openings in financial year 2023-24. The company's aggressive expansion led its portfolio to grow 19% in one year.

Bulbul Dhawan

The Skift India Newsletter is your go-to platform for all news related to travel, tourism, airlines, and hospitality in India.

Indian Hotels Company (IHCL) aimed for 300 hotels by 2025-26. But the parent company of Taj Hotels reached this goal two years early. The hotel group now has 309 hotels by the end of the 2023-24 financial year.

IHCL has aggressively expanded its footprint with 52 hotel signings and 34 openings last year, a significant increase from its 2022 numbers.

A significant contributor to the increased numbers during 2023 has been the partnership that IHCL has signed with Tree of Life Resorts & Hotels. Under the agreement, the company is offering its marketing and distribution network to the 14 properties of Tree of Life. 

IHCL has also ventured in East and Northeast India, with properties in Sikkim, Arunachal Pradesh, Odisha, and West Bengal.

The hotel group has also been focusing on large-format airport hotels. Its leisure and spiritual destination offerings also received a boost, with hotels signings in Bekal, Alibaug, Ayodhya and Haridwar.  

The company is betting big on its budget brand Ginger. It is the second-largest hotel brand under IHCL, after Taj. While Taj has 109 hotels in its portfolio, there are 90 hotels under the Ginger brand. In November last year, executive vice president (new businesses and hotel openings) Deepika Rao stated that IHCL was looking to have 86 operational hotels under the budget brand by the end of 2025-26 financial year. It currently has 64. 

It is also planning to bring a full-service brand in Tier 2 and Tier 3 cities to tap the mass market outside Indian metro cities. 

Rao said that the company’s expansion will increase domestically over the coming few years while it will foray into “select international markets.”

IHCL is also eyeing international expansion with new projects coming up in Dhaka, Bhutan, Nepal, and Frankfurt.

The openings and signings in 2023 across the various IHCL brands include:

The company signed 12 hotels under the luxury Taj brand. These include a 400-key airport at the Delhi International Airport, a 350-room hotel in Indore, Madhya Pradesh, a hotel in Dehradun, Uttarakhand, and two properties in Bhutan. 

Five Taj hotels were also opened:

• Taj Sewai, Ranthambore in Sawai Madhopur, Rajasthan
• Taj Taal Kutir in New Town, West Bengal
• Taj Guras Kutir Resort & Spa in Gangtok, Sikkim
• Taj The Trees, Mumbai in Maharashtra
• Taj Gandhinagar Resort & Spa in Gandhinagar, Gujarat

The company now has 84 hotels operating under the Taj brand with 25 properties in the pipeline. 

IHCL currently has 26 operational SeleQtion properties and 14 more under development. In 2023-24, 10 SeleQtion hotels were signed, including a 175-key hotel in Surat, Gujarat, a property in Bandra, Mumbai, a hotel in Ayodhya, Uttar Pradesh, and an 88-room resort in Naukuchiatal, Uttarakhand. 

The six openings are:

• Scenic Munnar in Munnar, Kerala
• Ekante Bliss in Tirupati, Andhra Pradesh
• Gorbandh Palace in Jaisalmer, Rajasthan
• WOW Crest in Indore, Madhya Pradesh
• The Crown in Bhubaneswar, Odisha
• The Yellow House in Anjuna, Goa

In 2023-24, IHCL maintained the momentum of 2022-23 with regard to the upscale Vivanta brand. While in the 2022-23 financial year, IHCL signed nine hotels under the Vivanta brand, the 2024 financial year saw this number increasing marginally to 10. These include hotels in Talegaon, Pune; Itanagar, Arunachal Pradesh; Ujjain, Madhya Pradesh; and Haridwar, Uttarakhand during the period. 

Like the year before, three Vivanta hotels also opened the 2024 financial year, of which two are located in India, and one in Nepal. 

• Vivanta Chitwan in Bharatpur, Nepal
• Vivanta Arunachal Pradesh in Tawang, Arunachal Pradesh
• Vivanta Jammu, City Centre in Jammu and Kashmir

The company currently operates 30 Vivanta hotels with 26 in the pipeline. 

With 64 Ginger hotels currently operational, IHCL signed six Ginger hotels in 2023-24, including a 300-key hotel at Goa’s new Manohar International Airport (MOPA), and one in Dibrugarh, Assam. With this there are 26 Ginger hotels in the pipeline.

The six Ginger hotel opening during this period were:

• Ginger Durgapur in Durgapur, West Bengal 
• Ginger Mumbai Airport in Mumbai, Maharashtra
• Ginger Gangtok, Bojoghari in Gangtok, Sikkim
• Ginger Noida, Sector 133 in Noida, Uttar Pradesh
• Ginger Kochi, MG Road in Kochi, Kerala
• Ginger Ahmedabad in Changodar, Gujarat

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Tags: airport hotels , bengaluru , boutique hotels , budget hotels , chalet hotels , delhi , delhi airport , Gujarat , hospitality , hospitality news , hotels , india , india travel , Indian Hotels Company , kerala , luxury hotels , luxury travel , mumbai , skift india report , small cities , taj hotels , tata , Tata Group , tourism , Travel Trends , west bengal

Photo credit: IHCL opened Scenic Munnar — IHCL SeleQtions hotel in Kerala last month. IHCL