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quinoline synthesis

quinoline synthesis

RSC Advances

Recent advances in the synthesis of quinolines: a review.

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a Department of Chemistry, School of Sciences, Gujarat University, Ahmedabad, Gujarat, India E-mail: [email protected] Fax: +91-079-26308545 Tel: +91-079-26300969

Quinolines have become important compounds because of their variety of applications in medicinal, synthetic organic chemistry as well as in the field of industrial chemistry. In recent years there are greater societal expectations that chemists should produce greener and more sustainable chemical processes. This review article gives information about the green and clean syntheses using alternative reaction methods for the synthesis of quinoline derivatives. The article includes synthesis by microwave, using clay or some other catalyst which could be recycled and reused, one-pot reaction, solvent-free reaction conditions, using ionic liquids, ultrasound promoted synthesis and photocatalytic synthesis (UV radiation).

Graphical abstract: Recent advances in the synthesis of quinolines: a review

  • This article is part of the themed collections: Organic chemist’s toolbox and Chemistry for Medicine: Special Collection for RSC Advances

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quinoline synthesis

S. M. Prajapati, K. D. Patel, R. H. Vekariya, S. N. Panchal and H. D. Patel, RSC Adv. , 2014,  4 , 24463 DOI: 10.1039/C4RA01814A

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IMAGES

  1. Quinoline synthesis methods: Skraup reaction (A); Doebner reaction (B);...

    quinoline synthesis

  2. Synthesis and Reactions of Quinoline

    quinoline synthesis

  3. Quinoline Synthesis

    quinoline synthesis

  4. Brønsted acid-catalyzed metal- and solvent-free quinoline synthesis from N -alkyl anilines and

    quinoline synthesis

  5. Camps Quinoline Synthesis

    quinoline synthesis

  6. Scheme 2. Proposed mechanism for the synthesis of quinoline derivatives...

    quinoline synthesis

VIDEO

  1. Easy to Learn Quinoline Synthesis || Heterocyclic Chemistry

  2. Quinoline synthesis 1

  3. Quinoline Synthesis and chemical properties

  4. Reactions of Quinoline & Isoquinoline

  5. Heterocyclic compounds lecture 3 and 4

  6. Properties of Quinoline

COMMENTS

  1. Quinoline

    Friedländer synthesis using 2-aminobenzaldehyde and acetaldehyde; Knorr quinoline synthesis, using a β-ketoanilide and sulfuric acid; Niementowski quinoline synthesis, using anthranilic acid and ketones; Pfitzinger reaction using an isatin with base and a carbonyl compound to yield substituted quinoline-4-carboxylic acids

  2. Recent advances in the synthesis of biologically and

    dilute HCl to prepare quinoline-4-carboxylic acid (28) in good to excellent yields.7 The authors claimed that using enaminone as a replacement for 1,3-dicarbinols improves the yield and prac-ticality of the reaction. 2.5. Skraup/Doebner–von Miller quinoline synthesis A synthesis of quinoline via aniline and glycerine in the pres-

  3. Recent advances in the synthesis of quinolines: a review

    This review article gives information about the green and clean syntheses using alternative reaction methods for the synthesis of quinoline derivatives. The article includes synthesis by microwave, using clay or some other catalyst which could be recycled and reused, one-pot reaction, solvent-free reaction conditions, using ionic liquids ...