brian e. lacy md phd jacksonville

Brian E. Lacy, M.D., Ph.D.

• Gastroenterologist
• Neurogastroenterologist

Departments

• Gastroenterology and Hepatology

Specialty Groups

• Motility Clinic

Jacksonville, Florida

Existing patients.

• Send a secure message via patient portal
• Biographical summary

Dr. Brian E. Lacy is a board certified gastroenterologist who focuses his research and clinical interests on disorders of gastrointestinal motility.

Dr. Lacy's areas of expertise include gastroesophageal reflux disease, dysphagia, achalasia, dyspepsia, gastroparesis, irritable bowel syndrome, constipation, intestinal pseudo-obstruction and visceral pain.

Dr. Lacy is the author of over 165 peer-reviewed articles on gastrointestinal motility disorders and functional bowel disorders, has written and/or edited 6 books on gastrointestinal motility disorders and functional bowel disorders, and has written multiple text book chapters.

Dr. Lacy is the current co-Editor in Chief of the American Journal of Gastroenterology. He is the former Editor in Chief of Clinical and Translational Gastroenterology. Dr. Lacy was the co-Chairman for the Rome IV Committee on Functional Bowel Disorders.

• Conditions treated
• Constipation
• Functional dyspepsia
• Gastroesophageal reflux disease
• Gastroparesis
• Indigestion
• Intestinal pseudo-obstruction
• Irritable bowel syndrome
• Pelvic floor dysfunction
• Small intestinal bacterial overgrowth
• Visceral pain
• Procedures performed
• Anorectal manometry
• Bravo capsule pH test
• Breath testing
• Colonoscopy
• Esophageal manometry
• Gastric emptying study
• Gastrointestinal transit study
• Impedance pH testing
• Upper endoscopy
• Intestinal Pseudo-obstruction
• Nausea and vomiting
• Pelvic Floor dysfunction
• Mayo Clinic locations

• Billing & insurance
• Accessibility services
• 1991 MD University of Maryland School of Medicine
• 1987 Ph.D. - Department of Anatomy and Cell Biology Georgetown University
• 1981 BA University of Virginia
• Activities and honors

Certifications

• 2002 Gastroenterology American Board of Internal Medicine

Awards and honors

• 2017 New Hampshire Top Doctor Award New Hampshire Top Doctor
• 1993 Dr. Thomas P. Almy Housestaff Teaching Award Almy Housestaff Teaching Award
• 1986 Dr. B. Raj Bhussry Memorial Scholarship Bhussry Memorial Scholarship
• 1985 First Place Student Research Forum Georgetown University
• 1985 Summer Research Fellowship Georgetown University
• 1984 NIH Predoctoral Training Fellowship Georgetown University

Professional memberships

• 2021 - present Research Committee American College of Gastroenterology
• 2018 - present Chair Motility / Functional GI Disorders Case Conference
• 2017 Co-Director Functional and GI Motility Disorders, Massachusetts General Hospital
• 2015 Co-Director Functional and GI Motility Disorders, Massachusetts General Hospital
• 2015 Co-Director Regional Update, American College of Gastroenterology
• 2014 Co-Director Functional and GI Motility Disorders, Massachusetts General Hospital
• 2014 Co-Director Pancreas Update, Dartmouth-Hitchcock Medical Center
• 2014 Abstract Reviewer Chair American College of Gastroenterology
• 2013 Co-Director Functional and GI Motility Disorders, Massachusetts General Hospital
• 2013 Co-Director Update in Gastroenterology & Hepatology
• 2013 - 2016 Education Committee Member American College of Gastroenterology
• 2012 Co-Director Functional and GI Motility Disorders, Massachusetts General Hospital
• 2012 - 2016 Co-Chairman Functional Bowel Disorders, International Rome Committee
• 2012 Co-Director Update in Gastroenterology & Hepatology
• 2011 Co-Director Update in Gastroenterology & Hepatology
• 2010 Co-Director Challenges in Functional GI Disease and Dysmotility, Massachusetts General Hospital
• 2010 - 2017 Board Chairman Data Safety Monitoring Board, National Institutes of Health
• 2010 - 2013 Abstract Selection Reviewer American College of Gastroenterology
• 2010 Co-Director Update in Gastroenterology & Hepatology, Dartmouth-Hitchcock Medical Center
• 2010 Co-Director Update in Gastroenterology & Hepatology
• 2009 Co-Director Update in Gastroenterology & Hepatology
• 2009 - 2012 Grant Reviewer International Rome Committee
• 2008 Co-Director GI Motility Update, Harvard University
• 2008 Co-Director Update in Gastroenterology & Hepatology
• 2008 - 2013 Member Public Relations Committee, American College of Gastroenterology
• 2008 - 2011 Committee Member Space Committee, Dartmouth-Hitchcock Medical Center
• 2008 - 2011 Member Education Committee, American Gastroenterological Association
• 2008 - 2010 Committee Member Pathology Chair Search Committee, Dartmouth-Hitchcock Medical Center
• 2008 - 2010 Chair Publications Committee, American College of Gastroenterology
• 2008 - 2009 Committee Member Pediatric GI Search Committee, Dartmouth-Hitchcock Medical Center
• 2008 Committee Member Self assessment Test, Recertification, American College of Gastroenterology
• 2007 Co-Director GI Motility Update, Harvard University
• 2007 Co-Director Esophageal Reflux and Motility Update, Yale University
• 2007 Co-Director Update in Gastroenterology & Hepatology
• 2007 - 2009 Secretary Hitchcock Foundation, Dartmouth-Hitchcock Medical Center
• 2007 Committee Member Surgery Search Committee, Dartmouth-Hitchcock Medical Center
• 2007 Education Committee American Gastroenterological Association
• 2006 Co-Director Harvard Annual Review on Gastrointestinal Motility Disorders
• 2006 Co-Director Update in Gastroenterology & Hepatology
• 2006 Director Update on Functional Gastrointestinal Disorders and Cardiology
• 2005 Co-Director Update in Gastroenterology & Hepatology
• 2005 - 2007 Council Functional Brain-Gut Research Group
• 2005 - 2007 Council Functional Brain Gut Research Group
• 2005 Abstract Selection Reviewer American Gastroenterological Association
• 2004 - 2018 Member Hitchcock Foundation, Dartmouth-Hitchcock Medical Center
• 2004 - 2018 Committee Member Schumann Lecture Committee, Dartmouth-Hitchcock Medical Center
• 2004 - 2006 Abstract Selection Reviewer American College of Gastroenterology
• 2004 Abstract Selection Reviewer American Gastroenterological Association
• 2003 - 2008 Member Education Committee, American College of Gastroenterology
• 2003 - 2008 Education Committee Member American College of Gastroenterology
• 2001 Member Functional Brain Gut Research Group
• 2000 Member American Motility Society
• 1999 - present Abstract Selection Committee American College of Gastroenterology
• 1998 - 1999 Abstract Selection Reviewer American College of Gastroenterology
• 1997 - 2000 Resident Johns Hopkins Bayview Medical Center
• 1997 - 1999 Research and Education Committee Chesapeake, Johns Hopkins Bayview Medical Center
• 1995 Member American College of Gastroenterology
• 1995 Member American Gastroenterological Association
• 1995 Member American Society of Gastrointestinal Endoscopy
• 1994 Member Alpha Omega Alpha

Publications

• Doctors & Medical Staff
• Lacy, Brian E. M.D., Ph.D.

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Dr. Brian E. Lacy MD

Gastroenterology

Mayo Clinic-Florida

Patient Rating

21 + Years of Experience

Practices at

a U.S. News Best Hospital

Patient Awards

in 4 condition s

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Accepting New Patients

4500 San Pablo Road S , Jacksonville , FL

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Mayo clinic jacksonville.

Doctor's Details

Specialties

Subspecialties

Advanced Endoscopic Interventional

Esophagus disease, patient experience.

Provides clear explanation

Makes time for patients

Listens attentively

Practices at Best Hospital

Provides clear information and answers questions in a way patients understand.

Spends appropriate amount of time with patient and provides thorough examinations.

Rated highly on their manner and listening skills.

This doctor practices at a U.S. News Best Regional Hospital

Overall Patient Experience

Very Positive

30 Reviews Total | 1 Reviews Within Last 12 Months

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Ability to Answer Questions

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Provider's follow-up

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Provider's Attitude

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Perceived Outcomes

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Areas of expertise for dr. lacy.

This doctor provides the following types of care. The more often a doctor has treated a particular condition or has performed a particular surgery, the more expertise they may have in treating patients with similar needs. Based on three years (2020-2022) of Medicare data, each scale below indicates the volume of episodes compared to other doctors who treat the same condition. Click here to learn more about our methodology.

Upper GI endoscopy Upper GI endoscopy is a procedure to visualize and examine the upper digestive tract.

Colonoscopy A colonoscopy is a procedure to visualize and examine the colon for abnormalities.

Acid reflux Acid reflux, aslo known as esophagitis or GERD, occurs when stomach acid flows back into the esophagus, causing a burning sensation in the chest (heartburn).

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Location & Contact Information

Doctor Address

4500 San Pablo Road S, Jacksonville, FL, 32224

Affiliated Hospitals

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Hospital Affiliations

Mayo clinic-florida jacksonville, fl.

# 24 in Gastroenterology & GI Surgery

High Performing in Colon Cancer Surgery

Education & Experience

Medical school & residency.

Dartmouth-Hitchcock/Mary Hitchcock Memorial Hospital

Fellowship , Gastroenterology , 1995 - 1997

University of Maryland School of Medicine

Medical School

Residency , Internal Medicine , 1991 - 1995

Certifications & Licensure

American Board of Internal Medicine

Certified in Gastroenterology

NH State Medical License

Active through 2018

MD State Medical License

Active through 2004

FL State Medical License

Active through 2026

Publications

Treatment-Free Interval: A Novel Approach to Assessing Real-World Treatment Effectiveness and Economic Impact Among Patients with Irritable Bowel Syndrome with Diarrhea.

Patrick Gagnon-Sanschagrin, Zeev Heimanson, Rebecca Bungay, Remi Bellefleur, Annie Guérin, Brock Bumpass, Danellys Borroto, George Joseph, Ankur A Dashputre, Brian E Lacy

Abdominal Symptom Improvement During Clinical Trials of Tenapanor in Patients With Irritable Bowel Syndrome With Constipation: A Post Hoc Analysis.

Yang, Y., Zhao, S., Rosenbaum, D., Lembo, A., Chey, W., Harris, L., Frazier, R., Brenner, D., Chang, L., Lacy, B., Edelstein, S.

Prokinetics-safety and efficacy: The European Society of Neurogastroenterology and Motility/The American Neurogastroenterology and Motility Society expert review.

Serhat Bor, İsmail H Kalkan, Edoardo Savarino, Satish Rao, Jan Tack, Jay Pasricha, David Cangemi, Jolien Schol, Tennekon Karunaratne, Matteo Ghisa, Nitin K Ahuja, Brian Lacy

Burnout in Gastrointestinal Providers.

Lacy, B., Cangemi, D., Burke, C.

Irritable bowel syndrome - less irritable, or better treatments?

Travers, P., Lacy, B., Cangemi, D.

Prevalence and patterns of laxative use in subjects with self-reported constipation: results from a multinational digestive health survey.

Brian E Lacy, Régis Delfini, Bernward Fladung, Robert Lange

Virtual Reality Improves Symptoms of Functional Dyspepsia: Results of a Randomized, Double-Blind, Sham-Controlled, Pilot Study.

David J Cangemi, Marilia Montenegro, Brennan M R Spiegel, And Brian E Lacy

Gastroparesis: time for a paradigm change.

Brian E Lacy, Journey L Wise, David J Cangemi

Misdiagnosis of Gastroparesis is Common: A Retrospective Review of Patients Referred to a Tertiary Gastroenterology Practice.

David J Cangemi, Lilly Stephens, Brian E Lacy

Rifaximin Treatment for Individual and Multiple Symptoms of Irritable Bowel Syndrome With Diarrhea: An Analysis Using New End Points.

Brian E Lacy, Lin Chang, Satish S C Rao, Zeev Heimanson, Gregory S Sayuk

De-escalate Don't Escalate: Essential Steps to Effectively Recognize and Manage the Patient Who Is Angry and Disruptive.

Brian E Lacy, Laurie Keefer, Douglas A Drossman

Virtual Reality: A New Treatment Paradigm for Disorders of Gut-Brain Interaction?

Brian E Lacy, David J Cangemi, Brennan R Spiegel

Gastroparesis: Myths, Misconceptions, and Management.

David J Cangemi, Brian E Lacy

The treatment of functional dyspepsia: present and future.

Brian E Lacy, R Christopher Chase, David J Cangemi

How Your Writing Can Succeed: Getting a Manuscript Accepted by The American Journal of Gastroenterology

George F Longstreth, Heather M Patton, Brian E. Lacy

Lymphocytic Esophagitis: Assessing Risk Factors and Clinical Outcomes

Himesh Zaver, Hassan Ghoz, Balkishan Malviya, Bhaumik Brahmbhatt, William C. Palmer, Brian E. Lacy, Kenneth R. DeVault, Murli Krishna, Yan Bi

70-Year-Old Man With Chronic Nausea and Vomiting.

Varun Moktan, Kimberly Robelin, Brian E. Lacy

AGA Clinical Practice Update on Management of Medically Refractory Gastroparesis: Expert Review

Brian E. Lacy, Jan Tack, C. Prakash Gyawali

The Changing Landscapes" Special Edition."

Brian E. Lacy, Brennan Spiegel

Gastric Emptying Scans: Poor Adherence to National Guidelines

Journey Wise, Maria I. Vazquez-Roque, Caleb J. McKinney, Michael A. Zickella, Michael D. Crowell, Brian E. Lacy

Efficacy of Linaclotide in Reducing Abdominal Symptoms of Bloating, Discomfort, and Pain: A Phase 3B Trial Using a Novel Abdominal Scoring System.

Lin Chang, Brian E. Lacy, Baha Moshiree, Amy Kassebaum, Jessica L. Abel, Jennifer Hanlon, Wilmin Bartolini, Ramesh Boinpally, Wieslaw Bochenek, Susan M. Fox, Madhuja Mallick, Ken Tripp, Nicholas Omniewski, Elizabeth P. Shea, Niels Borgstein

Controversies in Gastroparesis: Discussing the Sticky Points.

Brian E. Lacy, David J. Cangemi

Extent of eosinophilic esophagitis predicts response to treatment

Hassan Ghoz, Fernando F. Stancampiano, Jose Valery, Katie Nordelo, Balkishan Malviya, Brian E. Lacy, Dawn L. Francis, Kenneth R. DeVault, Ernest P. Bouras, Murli Krishna, William C. Palmer

Systematic review and network meta-analysis: efficacy of licensed drugs for abdominal bloating in irritable bowel syndrome with constipation.

Alfred D. Nelson, Christopher J Black, Lesley A. Houghton, Nahyr Sofía Lugo-Fagundo, Brian E. Lacy, Alexander C. Ford

Pyloric dilation with EsoFLIP: Time to "flip" treatment options for refractory gastroparesis?

Editorial: recognising the efficacy of licensed drug therapies for irritable bowel syndrome on bloating-a step in the right direction for targeted treatment? Authors' reply.

Eating Disorders: Diagnosis and Management Considerations for the IBD Practice.

Graziella Rangel Paniz, Jocelyn Lebow, Leslie Sim, Brian E. Lacy, Francis A Farraye, Monia E. Werlang

Diagnosing Small Intestinal Bacterial Overgrowth: A Comparison of Lactulose Breath Tests to Small Bowel Aspirates

David J. Cangemi, Brian E. Lacy, Journey Wise

Tegaserod for Irritable Bowel Syndrome With Constipation in Women Younger Than 65 Years Without Cardiovascular Disease: Pooled Analyses of 4 Controlled Trials.

Eric D. Shah, Brian E. Lacy, William D. Chey, Lin Chang, Darren M. Brenner

Re-evaluation of the Cardiovascular Safety Profile of Tegaserod: A Review of the Clinical Data.

Brian E. Lacy, Darren M. Brenner, William D. Chey

Antispasmodics for Chronic Abdominal Pain: Analysis of North American Treatment Options.

Darren M. Brenner, Brian E. Lacy

Post-marketing reports of pancreatitis in eluxadoline-treated patients pre and post US label change.

Brooks D. Cash, Brian E. Lacy, Cheryl Watton, Philip Schoenfeld, Darren Weissman

Satiation or satiety? More than mere semantics – Authors' reply

M Florencia Carbone, Sanjiv Mahadeva, Brian E. Lacy, Nicholas J. Talley, Alexander C. Ford

Gastric POEM for gastroparesis: Panacea, placebo, or pathway to the future?

Management of irritable bowel syndrome with diarrhea: focus on eluxadoline

Jennifer Jones, Anthony Lembo, Joel J. Heidelbaugh, Louis Kuritzky, Brian E. Lacy

Gastroparesis and Severity of Delayed Gastric Emptying: Comparison of Patient Characteristics, Treatments and Medication Adverse Events.

Christopher M. Navas, Erica D. Wadas, Michael D. Crowell, Brian E. Lacy

Management of Chronic Abdominal Distension and Bloating

Brian E. Lacy, David J. Cangemi, Maria I. Vazquez-Roque

Lessons learned: Chronic idiopathic constipation patient experiences with over-the-counter medications

Brian E. Lacy, Elizabeth P. Shea, Machelle Manuel, Jessica L. Abel, Hancheng Jiang, Douglas C.A. Taylor

Patients With Irritable Bowel Syndrome Are Willing to Take Substantial Medication Risks for Symptom Relief.

Shawn L. Shah, Nigeen H. Janisch, Michael D. Crowell, Brian E. Lacy

ACG Clinical Guideline: Management of Irritable Bowel Syndrome.

Brian E. Lacy, Mark Pimentel, Darren M. Brenner, William D. Chey, Laurie Keefer, Millie D. Long, Baha Moshiree

Update on Irritable Bowel Syndrome Guidelines.

Brian E. Lacy

Postobesity Surgery Esophageal Dysfunction: A Combined Cross-Sectional Prevalence Study and Retrospective Analysis

Alexander T. Miller, Reem Matar, Barham K. Abu Dayyeh, Azizullah Beran, Marcelo F. Vela, Brian E. Lacy, Michael D. Crowell, Debra M. Geno, Crystal Lavey, David A. Katzka, Karthik Ravi

Mechanisms, Evaluation, and Management of Chronic Constipation

Adil E. Bharucha, Brian E. Lacy

Management of irritable bowel syndrome with diarrhea: a review of nonpharmacological and pharmacological interventions

David J. Cangemi, Brian E. Lacy

Patient-Centric Care of Diarrhea-Predominant Irritable Bowel Syndrome.

Opioid-Induced Esophageal Dysfunction: Differential Effects of Type and Dose.

Diana L. Snyder, Michael D. Crowell, Jennifer L. Horsley-Silva, Karthik Ravi, Brian E. Lacy, Marcelo F. Vela

Gastrointestinal Manifestations of Rheumatological Diseases

Paul T. Kroner, Omar A. Tolaymat, Andrew W. Bowman, Andy Abril, Brian E. Lacy

Introduction to the Gut Microbiome Special Issue.

Response to Lai.

Brooks D. Cash, Brian E. Lacy, Philip Schoenfeld, Leonard S. Dove, Paul S. Covington

Functional Dyspepsia: Clinical Symptoms, Psychological Findings, and GCSI Scores.

Brian E. Lacy, Kelly Everhart, Michael D. Crowell

Letter: meta-analysis of prebiotics, probiotics, synbiotics and antibiotics in IBS. Authors’ reply

Alexander C. Ford, Lucinda A. Harris, Brian E. Lacy, Eamonn Martin Quigley, Paul Moayyedi

Impact of patient and disease characteristics on the efficacy and safety of eluxadoline for IBS-D: a subgroup analysis of phase III trials.

Brian E. Lacy, Lucinda A. Harris, Lin Chang, Susan Lucak, Catherine Gutman, Leonard S. Dove, Paul S. Covington, Anthony Lembo

A Novel, Duodenal-Release Formulation of a Combination of Caraway Oil and L-Menthol for the Treatment of Functional Dyspepsia: A Randomized Controlled Trial.

William D. Chey, Brian E. Lacy, Brooks D. Cash, Michael P. Epstein, Patrick Corsino, Syed M. Shah

Update on the management of chronic idiopathic constipation.

The willingness of patients with gastroparesis to take risks with medications.

Christopher M. Navas, Michael D. Crowell, Brian E. Lacy

Prokinetics for Functional Dyspepsia: A Systematic Review and Meta-Analysis of Randomized Control Trials.

Rapat Pittayanon, Yuhong Yuan, Natasha Bollegala, Reena Khanna, Brian E. Lacy, Christopher N. Andrews, Grigorios I. Leontiadis, Paul Moayyedi

Factors associated with more frequent diagnostic tests and procedures in patients with irritable bowel syndrome.

Brian E. Lacy, Rajeev Ayyagari, Annie Guerin, Andrea Lopez, Sherry Shi, Michelle Luo

Symptomatic Management of Gastroparesis.

Christopher M. Navas, Nihal Patel, Brian E. Lacy

Effect of Antidepressants and Psychological Therapies in Irritable Bowel Syndrome: An Updated Systematic Review and Meta-Analysis.

Alexander C. Ford, Brian E. Lacy, Lucinda A. Harris, Eamonn Martin Quigley, Paul Moayyedi

Irritable Bowel Syndrome and Dietary Interventions.

Monia E. Werlang, William C. Palmer, Brian E. Lacy

The Challenges of Gastroparesis: Changing Study Design to Improve Clinical Care.

Brian E. Lacy, Michael D. Crowell, Michael Camilleri

Systematic review with meta-analysis: the efficacy of prebiotics, probiotics, synbiotics and antibiotics in irritable bowel syndrome.

Introduction to the 80% by 2018 Special Issue

Review article: an analysis of safety profiles of treatments for diarrhoea-predominant irritable bowel syndrome.

American College of Gastroenterology Monograph on Management of Irritable Bowel Syndrome.

Alexander C. Ford, Paul Moayyedi, William D. Chey, Lucinda A. Harris, Brian E. Lacy, Yuri A. Saito, Eamonn Martin Quigley

Alosetron use in clinical practice: significant improvement in irritable bowel syndrome symptoms evaluated using the US Food and Drug Administration composite endpoint:

Brian E. Lacy, Jean Paul Nicandro, Emil Chuang, David L. Earnest

Management Options for Patients with GERD and Persistent Symptoms on Proton Pump Inhibitors: Recommendations from an Expert Panel

Rena Yadlapati, Michael F. Vaezi, Marcelo F. Vela, Stuart J. Spechler, Nicholas J. Shaheen, Joel E. Richter, Brian E. Lacy, David A. Katzka, Philip O. Katz, Peter J. Kahrilas, C. Prakash Gyawali, Lauren B. Gerson, Ronnie Fass, Donald O. Castell, Jenna Craft, Luke Hillman, John E. Pandolfino

Chronic nausea and vomiting: evaluation and treatment.

Brian E. Lacy, Henry P. Parkman, Michael Camilleri

Response to Marlicz et al.

Paul Moayyedi, Brian E. Lacy, Christopher N. Andrews, Robert A Enns, Colin W Howden, Nimish Vakil

Quality of Care and the Irritable Bowel Syndrome: Is Now the Time to Set Standards?

Brian E. Lacy, Alexander C. Ford, Nicholas J. Talley

Development of a Symptom-Focused Patient-Reported Outcome Measure for Functional Dyspepsia: The Functional Dyspepsia Symptom Diary (FDSD)

Fiona Taylor, Sophie Higgins, Robyn T. Carson, Sonya Eremenco, Catherine Foley, Brian E. Lacy, Henry P. Parkman, David S. Reasner, Alan L. Shields, Jan Tack, Nicholas J. Talley

Low-Dose Linaclotide (72 μg) for Chronic Idiopathic Constipation: A 12-Week, Randomized, Double-Blind, Placebo-Controlled Trial

Philip Schoenfeld, Brian E. Lacy, William D. Chey, Anthony Lembo, Caroline B. Kurtz, David S. Reasner, Wieslaw Bochenek, Kenneth Tripp, Mark G. Currie, Susan M. Fox, Rick Blakesley, Christopher R. O'Dea, Nicholas Omniewski, Michael Hall

Putting Patients First.

Brennan Spiegel, Brian E. Lacy

No Results? No Problem! Why We Are Publishing Methods of a Landmark Study With Results Still Pending

A System to Assess the Competency for Interpretation of Esophageal Manometry Identifies Variation in Learning Curves

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Safety of Eluxadoline in Patients with IBS-D Without a Gallbladder

Response to Croteau and Barkin.

Gastroparesis: Medical and Therapeutic Advances

ACG and CAG Clinical Guideline: Management of Dyspepsia

Paul Moayyedi, Brian E. Lacy, Christopher N. Andrews, Robert Enns, Colin W. Howden, Nimish Vakil

Polymorphisms of 5-HTT LPR and GNβ3 825C>T and Response to Antidepressant Treatment in Functional Dyspepsia: A Study from The Functional Dyspepsia Treatment Trial.

Yuri A. Saito, G. Richard Locke, Ann E. Almazar, Ernest P. Bouras, Colin W. Howden, Brian E. Lacy, John K. DiBaise, Charlene M. Prather, Bincy Abraham, Hashem B. El-Serag, Paul Moayyedi, Linda M. Herrick, Lawrence A. Szarka, Michael Camilleri, Frank A. Hamilton, Cathy D. Schleck, Katherine E. Tilkes, Alan R. Zinsmeister, Nicholas J. Talley

Eluxadoline Efficacy in IBS-D Patients Who Report Prior Loperamide Use

Brian E. Lacy, William D. Chey, Brooks D. Cash, Anthony Lembo, Leonard S. Dove, Paul S. Covington

Hot Topics in Primary Care: Role of the Microbiome in Disease: Implications for Treatment of Irritable Bowel Syndrome.

Safety of Eluxadoline in Patients with Irritable Bowel Syndrome with Diarrhea.

Update on the Management of Chronic Constipation

Jenna L. Koliani-Pace, Brian E. Lacy

Anatomy and Physiology of the Small Bowel

Neil R. Volk, Brian E. Lacy

Negative Is Positive.

Dietary Interventions and Irritable Bowel Syndrome: A Review of the Evidence

Shawn L. Shah, Brian E. Lacy

Bowel Disorders.

Fermín Mearin, Brian E Lacy, Lin Chang, William D Chey, Anthony J Lembo, Magnus Simren, Robin Spiller

Diagnosis and treatment of diarrhea-predominant irritable bowel syndrome.

The American Journal of Gastroenterology in 2016: Where Have We Been? Where Are We Going?

Rifaximin and eluxadoline - newly approved treatments for diarrhea-predominant irritable bowel syndrome: what is their role in clinical practice alongside alosetron?

Brooks D. Cash, Brian E. Lacy, Tharaknath Rao, David L. Earnest

Neuroenteric Stimulation for Gastroparesis

The Proton Pump Inhibitor Non-Responder: A Clinical Conundrum.

Zilla H Hussain, Emily E Henderson, Carla Maradey-Romerao, Nina George, Ronnie Fass, Brian E Lacy

Opioid-Induced Esophageal Dysfunction (OIED) in patients on chronic opioids

Shiva K. Ratuapli, Michael D. Crowell, John K. DiBaise, Marcelo F. Vela, Francisco C. Ramirez, George E. Burdick, Brian E. Lacy, Joseph A. Murray

New and Emerging Treatment Options for Irritable Bowel Syndrome

Brian E. Lacy, William D. Chey, Anthony Lembo

Medication Risk-Taking Behavior in Functional Dyspepsia Patients

Brian E. Lacy, Jerry Yu, Michael D. Crowell

Efficacy of prebiotics, probiotics, and synbiotics in irritable bowel syndrome and chronic idiopathic constipation: systematic review and meta-analysis.

Alexander C. Ford, Eamonn Martin Quigley, Brian E. Lacy, Anthony Lembo, Yuri A. Saito, Lawrence R. Schiller, Edy E. Soffer, Brennan Spiegel, Paul Moayyedi

The Effect of Fiber Supplementation on Irritable Bowel Syndrome: A Systematic Review and Meta-analysis

Paul Moayyedi, Eamonn Martin Quigley, Brian E. Lacy, Anthony Lembo, Yuri A. Saito, Lawrence R. Schiller, Edy E. Soffer, Brennan Spiegel, Alexander C. Ford

American College of Gastroenterology monograph on the management of irritable bowel syndrome and chronic idiopathic constipation.

Alexander C. Ford, Paul Moayyedi, Brian E. Lacy, Anthony Lembo, Yuri A. Saito, Lawrence R. Schiller, Edy E. Soffer, Brennan Spiegel, Eamonn Martin Quigley

Effect of Antidepressants and Psychological Therapies, Including Hypnotherapy, in Irritable Bowel Syndrome: Systematic Review and Meta-Analysis

On-demand hyoscine butylbromide for the treatment of self-reported functional cramping abdominal pain.

Brian E. Lacy, Fei Wang, Sujata Bhowal, Eckhard Schaefer

Functional Dyspepsia and Gastroparesis: One Disease or Two?

Chronic constipation: new diagnostic and treatment approaches.

Brian E. Lacy, John M. Levenick, Michael D. Crowell

Recent Advances in the Management of Difficult Constipation

IBS patients' willingness to take risks with medications.

Brian E. Lacy, Kelly Everhart, Kirsten Weiser, Ryan DeLee, Sebastian Strobel, Corey A. Siegel, Michael D. Crowell

A Prospective Study to Compare a Symptom-Based Reflux Disease Questionnaire to 48-h Wireless pH Monitoring for the Identification of Gastroesophageal Reflux (revised 2-26-11)

Brian E. Lacy, Robert Chehade, Michael D. Crowell

Clinical utility of the wireless pH capsule.

Brian E. Lacy, Andrew C. Dukowicz, Douglas J. Robertson, Julia E. Weiss, Pedro Teixeira, Maurice L. Kelley

Functional dyspepsia is associated with sleep disorders.

Functional dyspepsia: time to change clinical trial design?

Brian E. Lacy, Nicholas J. Talley, Michael Camilleri

The Diagnosis of Gastroesophageal Reflux Disease

Brian E. Lacy, Kirsten Weiser, Jocelyn D. Chertoff, Ronnie Fass, John E. Pandolfino, Joel E. Richter, Richard I. Rothstein, Chad Spangler, Michael F. Vaezi

Prucalopride for chronic constipation.

Brian E. Lacy, Burr J. Loew, Michael D. Crowell

The clinical utility of esophageal manometry.

Brian E. Lacy, Lisa Paquette, Douglas J. Robertson, Maurice L. Kelley, Julia E. Weiss

Common anorectal disorders: Diagnosis and treatment

Brian E. Lacy, Kirsten Weiser

Tolerability and clinical utility of the Bravo pH capsule in children.

Brian E. Lacy, Susan Edwards, Lisa Paquette, Julia E. Weiss, Maurice L. Kelley, Kim Ornvold

The treatment of irritable bowel syndrome.

Brian E. Lacy, Kirsten Weiser, Ryan De Lee

Lubiprostone: chronic constipation and irritable bowel syndrome with constipation

Brian E. Lacy, William D. Chey

How effective is tegaserod for the treatment of female patients with mixed subtype IBS

Lubiprostone: a novel treatment for chronic constipation.

Brian E. Lacy, L. Campbell Levy

Esophageal motility disorders: medical therapy

The effects of nebulized albuterol on esophageal function in asthmatic patients.

Brian E. Lacy, Carole Mathis, John DesBiens, Mark C. Liu

A 32-year-old woman with chronic abdominal pain.

Brian E. Lacy, Brooks D. Cash

Lubiprostone : A chloride channel activator

Safety and Tolerability of Transoral Bravo Capsule Placement After Transnasal Manometry Using a Validated Conversion Factor

Brian E. Lacy, Tracia O'Shana, Mary L. Hynes, Maurice L. Kelley, Julia E. Weiss, Lisa Paquette, Richard I. Rothstein

Gastrointestinal Motility Disorders: An Update

Gastric motility, gastroparesis, and gastric stimulation.

Age, specialty, and practice setting predict gastroesophageal reflux disease prescribing behavior.

Brian E. Lacy, Michael D. Crowell, Randal P Riesett, Amy M. Mitchell

Irritable bowel syndrome: a syndrome in evolution.

Brian E. Lacy, Ryan De Lee

Partnering With Gastroenterologists to Evaluate Patients With Chronic Constipation

Brian E. Lacy, Stephen A. Brunton

Irritable bowel syndrome: a primer on management.

Botulinum toxin for the treatment of gastroparesis: a preliminary report

Brian E. Lacy, Estephan N. Zayat, Michael D. Crowell, Marvin M. Schuster

Case Report: Botulinum Toxin in Hypertensive Lower Esophageal Sphincter: A Manometric Case Study

Brian E. Lacy, Estephan N. Zayat, Michael D. Crowell

Tegaserod: a new 5-HT4 agonist.

Brian E. Lacy, Shaoyong Yu

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Brian E. Lacy, Ph.D., M.D., FACG

Professor of Medicine, Mayo Clinic, Jacksonville

Activity Affiliations

• April 12, 2023 The Many Faces of Irritable Bowel Syndrome With Constipation: Incorporating Patient Perspectives Into Decisions Regarding Their Care

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Dr. Brian E. Lacy

Areas of expertise.

Many providers have expertise treating multiple conditions. MediFind uses a variety of data sources to determine what conditions a provider treats and their level of experience.

• Indigestion
• Irritable Bowel Syndrome (IBS)
• Bowel Incontinence
• Chronic Idiopathic Constipation (CIC)
• Gastroesophageal Reflux Disease (GERD)
• Gastroparesis
• Painful Swallowing
• Swallowing Difficulty
• Childhood Volvulus
• Esophagitis
• Gallbladder Removal
• Gas Bloat Syndrome
• Gastric Dysmotility
• Morning Sickness
• Small Bowel Bacterial Overgrowth
• Trichohepatoenteric Syndrome
• Viral Gastroenteritis
• Acute Pancreatitis
• Angiodysplasia of the Colon
• Attenuated Familial Adenomatous Polyposis
• Barrett Esophagus
• Benign Esophageal Stricture
• Childhood Pancreatitis
• Chronic Erosive Gastritis

About Dr. Brian E. Lacy

Brian Lacy is a Gastroenterologist in Jacksonville, Florida. MD. Lacy is highly rated in 23 conditions, according to our data. His top areas of expertise are Irritable Bowel Syndrome (IBS), Indigestion, Diarrhea, Gallbladder Removal, and Endoscopy. MD. Lacy is currently accepting new patients.

His clinical research consists of co-authoring 2 peer reviewed articles and participating in 9 clinical trials in the past 15 years.

MediFind strives to display the most accurate insurance information for every doctor. If you do not see your insurance listed for Dr. Brian E. Lacy it is best to call his office and ask if your insurance is accepted.

Dr. Brian E. Lacy accepts the following insurance:

•  Florida Blue

Background & Education

Clinical research.

Clinical research consists of overseeing clinical studies of patients undergoing new treatments and therapies, and publishing articles in peer reviewed medical journals. Providers who actively participate in clinical research are generally at the forefront of the fields and aware of the most up-to-date advances in treatments for their patients.

8 Clinical Trials

2 total publications, mayo clinic - florida.

Vivek Kumbhari is a Gastroenterologist in Jacksonville, Florida. Dr. Kumbhari is highly rated in 28 conditions, according to our data. His top areas of expertise are Achalasia, Gastrointestinal Fistula, Pancreatic Pseudocyst, Endoscopy, and Gastric Bypass. Dr. Kumbhari is currently accepting new patients.

Herbert Wolfsen is a Gastroenterologist in Jacksonville, Florida. Dr. Wolfsen is highly rated in 20 conditions, according to our data. His top areas of expertise are Barrett Esophagus, Hiatal Hernia, Congenital Diaphragmatic Hernia, Esophagitis, and Endoscopy. Dr. Wolfsen is currently accepting new patients.

Swathi Eluri is a Gastroenterologist in Jacksonville, Florida. Dr. Eluri has been practicing medicine for over 13 years is highly rated in 15 conditions, according to our data. Her top areas of expertise are Eosinophilic Esophagitis, Esophagitis, Barrett Esophagus, Endoscopy, and Colonoscopy. Dr. Eluri is currently accepting new patients.

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Brian Lacy, MD, PhD: Tailoring Treatment Experiences for IBS-C Patients

No catch-all drug works to treat irritable bowel syndrome with constipation. But as the Mayo Clinic expert explains, enough unique options exist to tailor care better than ever.

Irritable bowel syndrome (IBS) is an imperfectly managed condition. A number of unique pathway-target treatment options and cost-effective methods of symptom relief exist, but there is no great catch-all for the highly prevalent gastric disease.

But still, the armamentarium is growing vastly and quickly enough that a specialist may have the means to get more creative than they already are.

In the second segment of an interview with HCPLive during the American College of Gastroenterology (ACG) 2023 Annual Scientific Meeting in Vancouver, BC this week, Brian E. Lacy, MD, PhD, of the Mayo Clinic in Jacksonville, continued a discussion regarding tenapanor’s benefit for patients with IBS with constipation (IBS-C) by discussing the overall frustrating components of managing the chronic disease as both a provider and patient.

“We don't have a single agent that is effective for all IBS with constipation patients,” Lacy said. “I wish we did, but we don't. And we know that physiologically, patients are different. We know that different patients respond to different medications.”

Lacy explained a major component of his discussions with patients is to identify opportunities to personalize care; establishing a number of factors that which could influence treatment response and disease management could include any of these physician-to-patient questions:

• What have you taken before?
• What side effects did you experience?
• What are your goals and expectations from treatment?
• Do you understand the likelihood of response to this treatment?
• Do you understand how long this treatment generally takes to provide benefit?
• Do you understand the side effects associated with this treatment?

Lacy advocated for greater implementation of augmented therapy plans: combination pharmaceutical, diet and behavioral planning that reflects the patient’s current disease status.

“If somebody's partially responded to diet therapy, but not completely, don't necessarily stop the diet—but layer on something else,” Lacy said. “If somebody's partially responded, as an example, to tenapanor, but bloating isn't quite controlled, maybe layer on a new diet. And so you can imagine a number of different combinations of medications with diet.”

Lacy pointed to polyethylene glycol agents including Miralax—a common chronic constipation treatment that’s highly effective, safe and affordable. But for a patient with IBS-C, it may not be enough to address the key symptoms of abdominal pain and bloating.

“And so part of the dialogue with any IBS with constipation patient is setting expectations, but also limitations of certain medications,” Lacy said. “And when I think about treating the IBS patient, I want to think about global symptom relief: constipation, but the cardinal symptoms of abdominal pain and discomfort, and also bloating.”

Regarding tenapanor, Lacy expressed interest in observing its benefit to treat and relieve symptoms of constipation across other potential spaces—including patients with chronic constiptation, or those who experience it as a comorbidity due to Parkinson disease or opioid-induced constipation.

“That will require large studies to lead to FDA approval, but it’s certainly very interesting,” Lacy said. “And don't forget too—this medication has been shown to improve visceral pain. So is there something going on that maybe we could use this for other painful conditions, as well?”

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Brian Lacy, MD, PhD Mayo Clinic

Brian E. Lacy, Ph.D., M.D., FACG is currently Professor of Medicine and Consultant at Mayo Clinic Jacksonville. He is the Program Director of the GI Fellowship, and is Associate Program Director for Scholarly Activities for the Medical Residency Program. He previously worked at the Dartmouth-Hitchcock Medical Center where he was Section Chief of Gastroenterology and Hepatology and Professor of Medicine at the Geisel School of Medicine at Dartmouth. Dr. Lacy’s clinical and basic science research interests focus on disorders of gastrointestinal motility, with an emphasis on irritable bowel syndrome, dyspepsia, gastroparesis, acid reflux disease, constipation, achalasia, intestinal pseudo-obstruction and visceral pain. He is the author of over 240 peer-reviewed articles on gastrointestinal motility disorders and functional bowel disorders, in addition to multiple textbook chapters.  Dr. Lacy is a reviewer for many scientific journals, and is a member of a number of different scientific organizations, including the American College of Gastroenterology, the American Gastroenterology Association, and the American Neurogastroenterology & Motility Society.  Dr. Lacy is the co-author of a book for the general public on acid reflux disease, "Healing Heartburn", is the author of "Making Sense of IBS", a book for the general public on irritable bowel syndrome, and he edited and authored the books "Curbside Consultations in IBS", “Functional and Motility Disorders of the Gastrointestinal Tract” and “Essential Disorders of the Stomach and Small Intestine” for health care providers. Dr. Lacy recently finished a 6-year tenure as co-Editor in Chief of the American Journal of Gastroenterology. He is the former Editor in Chief of Clinical and Translational Gastroenterology. Dr. Lacy was the co-Chairman for the Rome IV Committee on Functional Bowel Disorders. He is on the Board of Trustees for the Rome Committee. Dr. Lacy received his doctorate in cell biology from Georgetown University in Washington, DC, and his medical degree from the University of Maryland in Baltimore.  Dr. Lacy was a resident in Internal Medicine at the Dartmouth-Hitchcock Medical Center in Lebanon, NH, where he continued his training as Chief Resident and as a Fellow in Gastroenterology.  He is board certified in Gastroenterology and Hepatology.

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Brian E Lacy PhD, MD, FACG

Professor of medicine , mayo clinic.

Brian E. Lacy, Ph.D., M.D., FACG is currently Consultant and Professor of Medicine at Mayo Clinic Jacksonville. He previously worked at the Dartmouth-Hitchcock Medical Center where he was Section Chief of Gastroenterology and Hepatology and Professor of Medicine at the Geisel School of Medicine at Dartmouth.

Dr. Lacy’s clinical and basic science research interests focus on disorders of gastrointestinal motility, with an emphasis on irritable bowel syndrome, achalasia, dyspepsia, gastroparesis, acid reflux disease, constipation, intestinal pseudo-obstruction and visceral pain. He is the author of over 200 peer-reviewed articles on gastrointestinal motility disorders and functional bowel disorders, in addition to multiple text book chapters. Dr. Lacy is a reviewer for a number of scientific journals, and is a member of a number of different scientific organizations, including the American College of Gastroenterology, the American Gastroenterology Association, and the American Neurogastroenterology & Motility Society. Dr. Lacy is the co-author of a book for the general public on acid reflux disease, "Healing Heartburn", is the author of "Making Sense of IBS", a book for the general public on irritable bowel syndrome, and edited and authored the books "Curbside Consultations in IBS", “Functional and Motility Disorders of the Gastrointestinal Tract” and “Essential Disorders of the Stomach and Small Intestine” for health care providers. Dr. Lacy is the current co-Editor in Chief of the American Journal of Gastroenterology. He is the former Editor in Chief of Clinical and Translational Gastroenterology. Dr. Lacy was the co-Chairman for the Rome IV Committee on Functional Bowel Disorders. He is on the Board of Trustees for the Rome Committee and the American College of Gastroenterology.

Dr. Lacy received his doctorate in cell biology from Georgetown University in Washington, DC, and his medical degree from the University of Maryland in Baltimore. Dr. Lacy was a resident in Internal Medicine at the Dartmouth-Hitchcock Medical Center in Lebanon, NH, where he continued his training as Chief Resident and as a Fellow in Gastroenterology. He is board certified in Gastroenterology and Hepatology.

Appearances

Meet Brian E. Lacy, Ph.D., M.D.

Published Works

Brian E. Lacy, Ph.D., M.D.

Lawrence J. Cheskin, M.D., F.A.C.P., and Brian E. Lacy, M.D., Ph.D.

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