- Support Our Work
The Smithsonian Institution's Human Origins Program
Malaria powerpoint slides final.
- Climate Effects on Human Evolution
- Survival of the Adaptable
- Human Evolution Timeline Interactive
- 2011 Olorgesailie Dispatches
- 2004 Olorgesailie Dispatches
- 1999 Olorgesailie Dispatches
- Olorgesailie Drilling Project
- Kanam, Kenya
- Kanjera, Kenya
- Ol Pejeta, Kenya
- Olorgesailie, Kenya
- Evolution of Human Innovation
- Adventures in the Rift Valley: Interactive
- 'Hobbits' on Flores, Indonesia
- Earliest Humans in China
- Bose, China
- Anthropocene: The Age of Humans
- Fossil Forensics: Interactive
- What's Hot in Human Origins?
- Instructions
- Carnivore Dentition
- Ungulate Dentition
- Primate Behavior
- Footprints from Koobi Fora, Kenya
- Laetoli Footprint Trails
- Footprints from Engare Sero, Tanzania
- Hammerstone from Majuangou, China
- Handaxe and Tektites from Bose, China
- Handaxe from Europe
- Handaxe from India
- Oldowan Tools from Lokalalei, Kenya
- Olduvai Chopper
- Stone Tools from Majuangou, China
- Middle Stone Age Tools
- Burin from Laugerie Haute & Basse, Dordogne, France
- La Madeleine, Dordogne, France
- Butchered Animal Bones from Gona, Ethiopia
- Katanda Bone Harpoon Point
- Oldest Wooden Spear
- Punctured Horse Shoulder Blade
- Stone Sickle Blades
- Projectile Point
- Oldest Pottery
- Pottery Fragment
- Fire-Altered Stone Tools
- Terra Amata Shelter
- Qafzeh: Oldest Intentional Burial
- Assyrian Cylinder Seal
- Blombos Ocher Plaque
- Ishango Bone
- Bone and Ivory Needles
- Carved Ivory Running Lion
- Female torso in ivory
- Ivory Horse Figurine
- Ivory Horse Sculpture
- Lady of Brassempouy
- Lion-Man Figurine
- Willendorf Venus
- Ancient Shell Beads
- Carved Bone Disc
- Cro-Magnon Shell Bead Necklace
- Oldest Known Shell Beads
- Ancient Flute
- Ancient Pigments
- Apollo 11 Plaque
- Carved antler baton with horses
- Geometric incised bone rectangle
- Tata Plaque
- Mystery Skull Interactive
- Shanidar 3 - Neanderthal Skeleton
- One Species, Living Worldwide
- Human Skin Color Variation
- Ancient DNA and Neanderthals
- Human Family Tree
- Swartkrans, South Africa
- Shanidar, Iraq
- Walking Upright
- Tools & Food
- Social Life
- Language & Symbols
- Humans Change the World
- Introduction to Human Evolution
- Nuts and bolts classification: Arbitrary or not? (Grades 6-8)
- Comparison of Human and Chimp Chromosomes (Grades 9-12)
- Hominid Cranial Comparison: The "Skulls" Lab (Grades 9-12)
- Investigating Common Descent: Formulating Explanations and Models (Grades 9-12)
- Fossil and Migration Patterns in Early Hominids (Grades 9-12)
- For College Students
- Why do we get goose bumps?
- Chickens, chimpanzees, and you - what do they have in common?
- Grandparents are unique to humans
- How strong are we?
- Humans are handy!
- Humans: the running ape
- Our big hungry brain!
- Our eyes say it!
- The early human tool kit
- The short-haired human!
- The “Nutcracker”
- What can lice tell us about human evolution?
- What does gut got to do with it?
- Why do paleoanthropologists love Lucy?
- Why do we have wisdom teeth?
- Human Origins Glossary
- Teaching Evolution through Human Examples
- Frequently Asked Questions
- Recommended Books
- Exhibit Floorplan Interactive
- Print Floorplan PDF
- Reconstructions of Early Humans
- Chesterfield County Public Library
- Orange County Library
- Andover Public Library
- Ephrata Public Library
- Oelwein Public Library
- Cedar City Public Library
- Milpitas Library
- Spokane County Library
- Cottage Grove Public Library
- Pueblo City-County Library
- Springfield-Greene County Library
- Peoria Public Library
- Orion Township Public Library
- Skokie Public Library
- Wyckoff Free Public Library
- Tompkins County Public Library
- Otis Library
- Fletcher Free Library
- Bangor Public Library
- Human Origins Do it Yourself Exhibit
- Exhibit Field Trip Guide
- Acknowledgments
- Human Origins Program Team
- Connie Bertka
- Betty Holley
- Nancy Howell
- Lee Meadows
- Jamie L. Jensen
- David Orenstein
- Michael Tenneson
- Leonisa Ardizzone
- David Haberman
- Fred Edwords (Emeritus)
- Elliot Dorff (Emeritus)
- Francisca Cho (Emeritus)
- Peter F. Ryan (Emeritus)
- Mustansir Mir (Emeritus)
- Randy Isaac (Emeritus)
- Mary Evelyn Tucker (Emeritus)
- Wentzel van Huyssteen (Emeritus)
- Joe Watkins (Emeritus)
- Tom Weinandy (Emeritus)
- Members Thoughts on Science, Religion & Human Origins (video)
- Science, Religion, Evolution and Creationism: Primer
- The Evolution of Religious Belief: Seeking Deep Evolutionary Roots
- Laboring for Science, Laboring for Souls: Obstacles and Approaches to Teaching and Learning Evolution in the Southeastern United States
- Public Event : Religious Audiences and the Topic of Evolution: Lessons from the Classroom (video)
- Evolution and the Anthropocene: Science, Religion, and the Human Future
- Imagining the Human Future: Ethics for the Anthropocene
- Human Evolution and Religion: Questions and Conversations from the Hall of Human Origins
- I Came from Where? Approaching the Science of Human Origins from Religious Perspectives
- Religious Perspectives on the Science of Human Origins
- Submit Your Response to "What Does It Mean To Be Human?"
- Volunteer Opportunities
- Submit Question
- "Shaping Humanity: How Science, Art, and Imagination Help Us Understand Our Origins" (book by John Gurche)
- What Does It Mean To Be Human? (book by Richard Potts and Chris Sloan)
- Bronze Statues
- Reconstructed Faces
Official websites use .gov
A .gov website belongs to an official government organization in the United States.
Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.
[Plasmodium falciparum] [Plasmodium knowlesi] [Plasmodium malariae] [Plasmodium ovale] [Plasmodium vivax]
Causal Agent
Blood parasites of the genus Plasmodium . There are approximately 156 named species of Plasmodium which infect various species of vertebrates. Four species are considered true parasites of humans, as they utilize humans almost exclusively as a natural intermediate host: P. falciparum, P. vivax, P. ovale and P. malariae . However, there are periodic reports of simian malaria parasites being found in humans, most reports implicating P. knowlesi . At the time of this writing, it has not been determined if P. knowlesi is being naturally transmitted from human to human via the mosquito, without the natural intermediate host (macaque monkeys, genus Macaca ). Therefore, P. knowlesi is still considered a zoonotic malaria.
Geographic Distribution
Malaria generally occurs in areas where environmental conditions allow parasite multiplication in the vector. Malaria today is usually restricted to tropical and subtropical areas and altitudes below 1,500 m., although in the past malaria was endemic in much of North America, Europe and even parts of northern Asia, and today is still present on the Korean peninsula. However, this present distribution could be affected by climatic changes and population movements. Plasmodium falciparum is the predominant species in the world. P. vivax and P. ovale are traditionally thought to occupy complementary niches, with P. ovale predominating in Sub-Saharan Africa and P. vivax in the other areas; but their geographical ranges do overlap. These two species are not always distinguishable on the basis of morphologic characteristics alone, and the use of molecular tools will help clarify their diagnosis and exact distribution. P. malariae has wide global distribution, being found in South America, Asia, and Africa, but it is less frequent than P. falciparum in terms of association with cases of infection. P. knowlesi is found in southeast Asia.
More on: Malaria Risk Information and Prophylaxis by Country
Clinical Presentation
The symptoms of uncomplicated malaria can be rather non-specific and the diagnosis can be missed if health providers are not alert to the possibility of this disease. Since untreated malaria can progress to severe forms that may be rapidly (<24 hours) fatal, malaria should always be considered in patients who have a history of exposure (mostly: past travel or residence in disease-endemic areas). The most frequent symptoms include fever and chills, which can be accompanied by headache, myalgias, arthralgias, weakness, vomiting, and diarrhea. Other clinical features include splenomegaly, anemia, thrombocytopenia, hypoglycemia, pulmonary or renal dysfunction, and neurologic changes. The clinical presentation can vary substantially depending on the infecting species, the level of parasitemia, and the immune status of the patient. Infections caused by P. falciparum are the most likely to progress to severe, potentially fatal forms with central nervous system involvement (cerebral malaria), acute renal failure, severe anemia, or acute respiratory distress syndrome. Other species can also have severe manifestations. Complications of P. vivax malaria include splenomegaly (with, rarely, splenic rupture), and those of P. malariae include nephrotic syndrome.
Ring-form trophozoites of P. falciparum in thick and a thin blood smear.
Ring-form trophozoites of P. falciparum in thin blood smears exhibiting Maurer’s clefts.
Developing and older trophozoites of P. falciparum in thick and a thin blood smear.
Gametocytes of P. falciparum in thick and a thin blood smear.
Schizonts of P. falciparum in a thin blood smear.
Ring-form trophozoites of P. knowlesi in a thin blood smear.
Older, developing trophozoites of P. knowlesi in a thin blood smear.
Gametocytes of P. knowlesi in thin blood smears.
Schizonts of P. knowlesi in a thin blood smear.
Ring-form trophozoites of P. malariae in thick and think blood smears.
Trophozoites of P. malariae in a thick blood smear.
Band-form trophozoites of P. malariae in a thin blood smear.
Basket-form trophozoites of P. malariae in a thin blood smear.
Gametocytes of P. malariae in thick and a thin blood smear.
Schizonts of P. malariae in thick and a thin blood smear.
Ring-form trophozoites of P. ovale in thick and a thin blood smear.
Trophozoites of P. ovale in thick and thin blood smears.
Gametocytes of P. ovale in thick and thin blood smears.
Schizonts of P. ovale in thick and thin blood smears.
Ring-form trophozoites of P. vivax in thick and thin blood smears.
Trophozoites of P. vivax in thick and thin blood smears.
Gametocytes of P. vivax in thick and thin blood smears.
Ookinetes of P. vivax in thick and thin blood smears.
Schizonts of P. vivax in thick and thin blood smears.
Diagnostic Findings
Microscopy (morphologic analysis) continues to be the “gold standard” for malaria diagnosis. Parasites may be visualized on both thick and thin blood smears stained with Giemsa, Wright, or Wright-Giemsa stains. Giemsa is the preferred stain, as it allows for detection of certain morphologic features (e.g. Schüffner’s dots, Maurer’s clefts, etc.) that may not be seen with the other two. Ideally, the thick smears are used to detect the presence of parasites while the thin smears are used for species-level identification. Quantification may be done on both thick and thin smears.
Molecular Diagnosis
Morphologic characteristics of malaria parasites can determine a parasite species, however, microscopists may occasionally fail to differentiate between species in cases where morphologic characteristics overlap (especially Plasmodium vivax and P. ovale ), as well as in cases where parasite morphology has been altered by drug treatment or improper storage of the sample. In such cases, the Plasmodium species can be determined by using confirmatory molecular diagnostic tests. In addition, molecular tests such as PCR can detect parasites in specimens where the parasitemia may be below the detectable level of blood film examination. The methods currently used at CDC are described below.
Species-specific PCR diagnosis of malaria
Plasmodium genomic DNA is extracted from 200 µl whole blood using the QIAamp Blood Kit (Cat. No. 29106; Qiagen Inc., Chatsworth, CA.) or a similar product that can yield the comparable concentration of genomic DNA from the same volume of blood.
Detection and identification of Plasmodium to the species level is done with a real-time PCR assay as described by Rougemont et al 2004. This is a dual duplex assay that detects P. falciparum and P. vivax in one reaction, and P. malariae and P. ovale in a parallel reaction, using species-specific TaqMan probes. In cases where infection by more than one Plasmodium species is suspected, there is an option to use a conventional nested PCR assay (Snounou el al, 1993) that has an improved resolution of mixed infection compared to the real-time PCR assay.
Agarose gel (2%) analysis of a PCR diagnostic test for species-specific detection of Plasmodium DNA. PCR was performed using nested primers of Snounou et al.1
- Lane S: Molecular base pair standard (50-bp ladder). Black arrows show the size of standard bands.
- Lane 1: The red arrow shows the diagnostic band for P. vivax (size: 120 bp).
- Lane 2: The red arrow shows the diagnostic band for P. malariae (size: 144 bp).
- Lane 3: The red arrow shows the diagnostic band for P. falciparum (size: 205 bp).
- Lane 4: The red arrow shows the diagnostic band for P. ovale (size: 800 bp).
Mathieu Rougemont, Madeleine Van Saanen, Roland Sahli, Hans Peter Hinrikson, Jacques Bille and Katia Jaton. Detection of Four Plasmodium Species in Blood from Humans by 18S rRNA Gene Subunit-Based and Species-Specific Real-Time PCR Assays. J. Clin. Microbiol. 2004, 42(12):5636.
Snounou G, Viriyakosol S, Zhu XP, et al. High sensitivity detection of human malaria parasites by the use of nested polymerase chain reaction. Mol Biochem Parasitol 1993;61:315-320.
Antibody Detection
Malaria antibody detection for clinical diagnosis is performed using the indirect fluorescent antibody (IFA) test. The IFA procedure can be used as a diagnostic tool to determine if a patient has been infected with Plasmodium . Because of the time required for development of antibody and also the persistence of antibodies, serologic testing is not practical for routine diagnosis of acute malaria. However, antibody detection may be useful for:
- screening blood donors involved in cases of transfusion-induced malaria when the donor’s parasitemia may be below the detectable level of blood film examination
- testing a patient who has been recently treated for malaria but in whom the diagnosis is questioned
Species-specific testing is available for the four human species: P. falciparum , P. vivax , P. malariae , and P. ovale . Cross reactions often occur between Plasmodium species and Babesia species. Blood stage Plasmodium species schizonts (meronts) are used as antigen. The patient’s serum is exposed to the organisms; homologous antibody, if present, attaches to the antigen, forming an antigen-antibody (Ag-Ab) complex. Fluorescein-labeled antihuman antibody is then added, which attaches to the patient’s malaria-specific antibodies. When examined with a fluorescence microscope, a positive reaction is when the parasites fluoresce an apple green color.
Sulzer AJ, and Wilson M. The fluorescent antibody test for malaria. Crit Rev Clin Lab Sci 1971;2:601-609.
Antigen Detection
In addition to microscopy and molecular methods, there are methods for detecting malaria parasites on the basis of antigens or enzymatic activities associated with the parasites. These methods are often packaged as individual test kits called rapid diagnostic tests or RDTs.
These methods include, among others:
- detection of an antigen (histidine rich protein-2, HRP-2) associated with malaria parasites ( P. falciparum )
- detection of a Plasmodium specific aldolase
- detection of a Plasmodium associated lactate dehydrogenase (pLDH) either through its enzymatic activity or by immunoassay
There is currently only one RDT licensed for use in the United States. For additional information visit https://www.cdc.gov/malaria/diagnosis_treatment/rdt.html
Treatment Information
Information about treatment of malaria in the United States is available at https://www.cdc.gov/malaria/diagnosis_treatment/index.html .
Malaria is transmitted to humans by female mosquitoes of the genus Anopheles. Female mosquitoes take blood meals for egg production, and these blood meals are the link between the human and the mosquito hosts in the parasite life cycle. The successful development of the malaria parasite in the mosquito (from the “gametocyte” stage to the “sporozoite” stage) depends on several factors. The most important is ambient temperature and humidity (higher temperatures accelerate the parasite growth in the mosquito) and whether the Anopheles survives long enough to allow the parasite to complete its cycle in the mosquito host (“ sporogonic ” or “extrinsic” cycle, duration 9 to 18 days). In contrast to the human host, the mosquito host does not suffer noticeably from the presence of the parasites .
Sequential images of the mosquito taking its blood meal
General Information
There are approximately 3,500 species of mosquitoes grouped into 41 genera. Human malaria is transmitted only by females of the genus Anopheles . Of the approximately 430 Anopheles species, only 30-40 transmit malaria (i.e., are “vectors”) in nature. The rest either bite humans infrequently or cannot sustain development of malaria parasites.
Anophelines are found worldwide except Antarctica. Malaria is transmitted by different Anopheles species in different geographic regions. Within geographic regions, different environments support a different species.
Anophelines that can transmit malaria are found not only in malaria-endemic areas, but also in areas where malaria has been eliminated. These areas are thus at risk of re-introduction of the disease.
Life Stages
Like all mosquitoes, anopheles mosquitoes go through four stages in their life cycle: egg, larva, pupa, and adult. The first three stages are aquatic and last 7-14 days, depending on the species and the ambient temperature. The biting female Anopheles mosquito may carry malaria. Male mosquitoes do not bite so cannot transmit malaria or other diseases. The adult females are generally short-lived, with only a small proportion living long enough (more than 10 days in tropical regions) to transmit malaria.
Adult females lay 50-200 eggs per oviposition. Eggs are laid singly directly on water and are unique in having floats on either side. Eggs are not resistant to drying and hatch within 2-3 days, although hatching may take up to 2-3 weeks in colder climates.
Mosquito larvae have a well-developed head with mouth brushes used for feeding, a large thorax, and a segmented abdomen. They have no legs. In contrast to other mosquitoes, Anopheles larvae lack a respiratory siphon and for this reason position themselves so that their body is parallel to the surface of the water.
Larvae breathe through spiracles located on the 8th abdominal segment and therefore must come to the surface frequently.
The larvae spend most of their time feeding on algae, bacteria, and other microorganisms in the surface microlayer. They do so by rotating their head 180 degrees and feeding from below the microlayer. Larvae dive below the surface only when disturbed. Larvae swim either by jerky movements of the entire body or through propulsion with the mouth brushes.
Larvae develop through 4 stages, or instars, after which they metamorphose into pupae. At the end of each instar, the larvae molt, shedding their exoskeleton, or skin, to allow for further growth.
The larvae occur in a wide range of habitats but most species prefer clean, unpolluted water. Larvae of Anopheles mosquitoes have been found in fresh- or salt-water marshes, mangrove swamps, rice fields, grassy ditches, the edges of streams and rivers, and small, temporary rain pools. Many species prefer habitats with vegetation. Others prefer habitats that have none. Some breed in open, sun-lit pools while others are found only in shaded breeding sites in forests. A few species breed in tree holes or the leaf axils of some plants.
The pupa is comma-shaped when viewed from the side. This is a transitional stage between larva and adult. The pupae does not feed, but undergoes radical metamorphosis. The head and thorax are merged into a cephalothorax with the abdomen curving around underneath. As with the larvae, pupae must come to the surface frequently to breathe, which they do through a pair of respiratory trumpets on the cephalothorax. After a few days as a pupa, the dorsal surface of the cephalothorax splits and the adult mosquito emerges onto the surface of the water.
The duration from egg to adult varies considerably among species and is strongly influenced by ambient temperature. Mosquitoes can develop from egg to adult in as little as 7 days but usually take 10-14 days in tropical conditions.
Like all mosquitoes, adult anopheles have slender bodies with 3 sections: head, thorax and abdomen.
The head is specialized for acquiring sensory information and for feeding. The head contains the eyes and a pair of long, many-segmented antennae. The antennae are important for detecting host odors as well as odors of aquatic larval habitats where females lay eggs. The head also has an elongate, forward-projecting proboscis used for feeding, and two sensory palps.
The thorax is specialized for locomotion. Three pairs of legs and a single pair of wings are attached to the thorax.
The abdomen is specialized for food digestion and egg development. This segmented body part expands considerably when a female takes a blood meal. The blood is digested over time serving as a source of protein for the production of eggs, which gradually fill the abdomen.
Anopheles mosquitoes can be distinguished from other mosquitoes by the palps, which are as long as the proboscis, and by the presence of discrete blocks of black and white scales on the wings. Adult Anopheles can also be identified by their typical resting position: males and females rest with their abdomens sticking up in the air rather than parallel to the surface on which they are resting .
Adult mosquitoes usually mate within a few days after emerging from the pupal stage. In some species, the males form large swarms, usually around dusk, and the females fly into the swarms to mate. The mating habitats of many species remain unknown.
Males live for about a week, feeding on nectar and other sources of sugar. Females will also feed on sugar sources for energy but usually require a blood meal for the development of eggs. After obtaining a full blood meal, the female will rest for a few days while the blood is digested and eggs are developed. This process depends on the temperature but usually takes 2-3 days in tropical conditions. Once the eggs are fully developed, the female lays them then seeks blood to sustain another batch of eggs.
The cycle repeats itself until the female dies. Females can survive up to a month (or longer in captivity) but most do not live longer than 1-2 weeks in nature. Their chances of survival depend on temperature and humidity, but also upon their ability to successfully obtain a blood meal while avoiding host defenses.
Factors Involved in Malaria Transmission and Malaria Control
Understanding the biology and behavior of Anopheles mosquitoes can aid in designing appropriate control strategies. Factors that affect a mosquito’s ability to transmit malaria include its innate susceptibility to Plasmodium , its host choice, and its longevity. Long-lived species that prefer human blood and support parasite development are the most dangerous. Factors that should be taken into consideration when designing a control program include the susceptibility of malaria mosquitoes to insecticides and the preferred feeding and resting location of adult mosquitoes.
More on: How to Reduce Malaria’s Impact
Preferred Sources for Blood Meals
One important behavioral factor is the degree to which an Anopheles species prefers to feed on humans (anthropophily) or animals such as cattle (zoophily). Anthrophilic Anopheles are more likely to transmit the malaria parasites from one person to another. Most Anopheles mosquitoes are not exclusively anthropophilic or zoophilic; many are opportunistic and feed upon whatever host is available. However, the primary malaria vectors in Africa, An. gambiae and An. funestus , are strongly anthropophilic and, consequently, are two of the most efficient malaria vectors in the world.
Once ingested by a mosquito, malaria parasites must undergo development within the mosquito before they are infectious to humans. The time required for development in the mosquito (the extrinsic incubation period) takes 9 days or longer, depending on the parasite species and the temperature. If a mosquito does not survive longer than the extrinsic incubation period, then she will not be able to transmit any malaria parasites.
It is not possible to measure directly the life span of mosquitoes in nature, but many studies have indirectly measured longevity by examination of their reproductive status or via marking, releasing, and recapturing adult mosquitoes. The majority of mosquitoes do not live long enough to transmit malaria, but some may live as long as three weeks in nature. Though evidence suggests that mortality rate increases with age, most workers estimate longevity in terms of the probability that a mosquito will live one day. Usually these estimates range from a low of 0.7 to a high of 0.9. If survivorship is 90% daily, then a substantial proportion of the population would live longer than 2 weeks and would be capable of transmitting malaria. Any control measure that reduces the average lifespan of the mosquito population will reduce transmission potential. Insecticides thus need not kill the mosquitoes outright, but may be effective by limiting their lifespan.
Patterns of Feeding and Resting
Most Anopheles mosquitoes are crepuscular (active at dusk or dawn) or nocturnal (active at night). Some Anopheles mosquitoes feed indoors (endophagic) while others feed outdoors (exophagic). After blood feeding, some Anopheles mosquitoes prefer to rest indoors (endophilic) while others prefer to rest outdoors (exophilic). Biting by nocturnal, endophagic Anopheles mosquitoes can be markedly reduced through the use of insecticide-treated bed nets (ITNs) or through improved housing construction to prevent mosquito entry (e.g., window screens). Endophilic mosquitoes are readily controlled by indoor spraying of residual insecticides. In contrast, exophagic/exophilic vectors are best controlled through source reduction (destruction of larval habitats).
Insecticide Resistance
Insecticide-based control measures (e.g., indoor spraying with insecticides, ITNs) are the principal way to kill mosquitoes that bite indoors. However, after prolonged exposure to an insecticide over several generations, mosquitoes, like other insects, may develop resistance, a capacity to survive contact with an insecticide. Since mosquitoes can have many generations per year, high levels of resistance can arise very quickly. Resistance of mosquitoes to some insecticides has been documented within a few years after the insecticides were introduced. There are over 125 mosquito species with documented resistance to one or more insecticides. The development of resistance to insecticides used for indoor residual spraying was a major impediment during the Global Malaria Eradication Campaign. Judicious use of insecticides for mosquito control can limit the development and spread of resistance, particularly via rotation of different classes of insecticides used for control. Monitoring of resistance is essential to alert control programs to switch to more effective insecticides.
Susceptibility/Refractoriness
Some Anopheles species are poor vectors of malaria, as the parasites do not develop well (or at all) within them. There is also variation within species. In the laboratory, it has been possible to select for strains of An. gambiae that are refractory to infection by malaria parasites. These refractory strains have an immune response that encapsulates and kills the parasites after they have invaded the mosquito’s stomach wall. Scientists are studying the genetic mechanism for this response. It is hoped that some day, genetically modified mosquitoes that are refractory to malaria can replace wild mosquitoes, thereby limiting or eliminating malaria transmission.
DPDx is an educational resource designed for health professionals and laboratory scientists. For an overview including prevention, control, and treatment visit www.cdc.gov/parasites/ .
To receive email updates about this page, enter your email address:
Exit Notification / Disclaimer Policy
- The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website.
- Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website.
- You will be subject to the destination website's privacy policy when you follow the link.
- CDC is not responsible for Section 508 compliance (accessibility) on other federal or private website.
- Ultimate Combo
- Sign Out Sign Out Sign In
20 Best Malaria-Themed Templates for PowerPoint & Google Slides
With over 6 million presentation templates available for you to choose from, crystalgraphics is the award-winning provider of the world’s largest collection of templates for powerpoint and google slides. so, take your time and look around. you’ll like what you see whether you want 1 great template or an ongoing subscription, we've got affordable purchasing options and 24/7 download access to fit your needs. thanks to our unbeatable combination of quality, selection and unique customization options, crystalgraphics is the company you can count on for your presentation enhancement needs. just ask any of our thousands of satisfied customers from virtually every leading company around the world. they love our products. we think you will, too" id="category_description">crystalgraphics creates templates designed to make even average presentations look incredible. below you’ll see thumbnail sized previews of the title slides of a few of our 20 best malaria templates for powerpoint and google slides. the text you’ll see in in those slides is just example text. the malaria-related image or video you’ll see in the background of each title slide is designed to help you set the stage for your malaria-related topics and it is included with that template. in addition to the title slides, each of our templates comes with 17 additional slide layouts that you can use to create an unlimited number of presentation slides with your own added text and images. and every template is available in both widescreen and standard formats. with over 6 million presentation templates available for you to choose from, crystalgraphics is the award-winning provider of the world’s largest collection of templates for powerpoint and google slides. so, take your time and look around. you’ll like what you see whether you want 1 great template or an ongoing subscription, we've got affordable purchasing options and 24/7 download access to fit your needs. thanks to our unbeatable combination of quality, selection and unique customization options, crystalgraphics is the company you can count on for your presentation enhancement needs. just ask any of our thousands of satisfied customers from virtually every leading company around the world. they love our products. we think you will, too.
Widescreen (16:9) Presentation Templates. Change size...
Slides enhanced with malaria written on a blackboard
Slides enhanced with sucking mosquito dangerous vehicle of zika dengue chikungunya malaria and other infections digital artwork on healthcare theme
PPT theme enhanced with anopheles mosquito dangerous vehicle of zika dengue chikungunya malaria and other infections insect isolated on white background backdrop
PPT theme consisting of sucking mosquito dangerous vehicle of zika dengue chikungunya malaria and other infections digital artwork on healthcare theme
Slides featuring anopheles mosquito with belly full of blood dangerous vehicle of zika dengue chikungunya malaria and other infections insect isolated on white background
Slide deck enhanced with mosquito on tropical beach dangerous vehicle of zika dengue chikungunya malaria and other infections digital artwork on pest and infection control theme
Theme featuring anopheles mosquito - dangerous vehicle of a malaria infection
Slides featuring stop malaria written on hand isolated on white background backdrop
PPT layouts with african child toddler sick with malaria medicine in the background laying down on a blanket in the yard
Presentation having mosquito isolated on white background
Presentation theme having lyme disease sign isolated on white background
Slides with malaria text on medical background with pills and syringes concept of human disease
Slide deck having mosquito isolated on white background being dead
PPT theme consisting of three mosquitoes isolated on white background
Slides consisting of malaria - parasitic infection transmitted by mosquitoes and can cause fever chills and organ failure
Presentation theme enhanced with allergies concept woman scratching arm closeup background
Slides enhanced with stop malaria written on hand with yellow background
PPT theme having mosquito isolated on white background being dead
PPT theme having mosquito isolated on white background
Presentation theme with malaria - parasitic infection transmitted by mosquitoes and can cause fever chills and organ failure background
More malaria presentation templates.
Company Info
- Health, Pharma & Medtech ›
State of Health
Industry-specific and extensively researched technical data (partially from exclusive partnerships). A paid subscription is required for full access.
Population at risk of malaria in Honduras 2010-2022
The population estimated to be at risk of contracting malaria in Honduras fluctuated between 17.1 and 90.9 percent during the period analyzed. In the last year depicted, 24.3 percent of the population in the country was considered at risk of contracting the disease.
Share of the population at risk of malaria in Honduras from 2010 to 2022
- Immediate access to 1m+ statistics
- Incl. source references
- Download as PNG, PDF, XLS, PPT
Additional Information
Show sources information Show publisher information Use Ask Statista Research Service
2010 to 2022
Other statistics on the topic
- Health care quality in selected Latin American countries 2023
- Zika virus cases in Brazil 2015-2023
- Countries with most malaria cases in Latin America 2022
- Zika virus cases in Latin America 2015-2023
To download this statistic in XLS format you need a Statista Account
To download this statistic in PNG format you need a Statista Account
To download this statistic in PDF format you need a Statista Account
To download this statistic in PPT format you need a Statista Account
As a Premium user you get access to the detailed source references and background information about this statistic.
As a Premium user you get access to background information and details about the release of this statistic.
As soon as this statistic is updated, you will immediately be notified via e-mail.
… to incorporate the statistic into your presentation at any time.
You need at least a Starter Account to use this feature.
- Immediate access to statistics, forecasts & reports
- Usage and publication rights
- Download in various formats
You only have access to basic statistics. This statistic is not included in your account.
- Instant access to 1m statistics
- Download in XLS, PDF & PNG format
- Detailed references
Business Solutions including all features.
Statistics on " Tropical diseases in Latin America "
- Healthcare spending in Latin America and the Caribbean 2020, by country
- Healthcare spending per capita in Latin America and the Caribbean 2020, by country
- GHS Index robust health system in Latin America 2021
- Availability of health care information in Latin America 2023
- Flooding risk index in Latin America & the Caribbean 2023, by country
- Epidemic risk index in Latin America & the Caribbean 2023, by country
- Vector-borne disease risk index in Latin America & the Caribbean 2023, by country
- People living in poverty and extreme poverty in Latin America 1990-2022
- Latin America: food insecurity prevalence 2014-2022, by severity
- Chikungunya cases in Latin America 2015-2023
- Chikungunya cases in Latin America 2023, by country
- Chikungunya cases in Brazil 2015-2023
- Chikungunya cases in Paraguay 2014-2023
- Chikungunya cases in Guatemala 2014-2023
- Dengue cases in Latin America & the Caribbean 2016-2024
- Dengue cases in Latin America & the Caribbean 2024, by country
- Dengue cases in Brazil 2015-2024
- Dengue cases in Nicaragua 2015-2024
- Dengue cases in Peru 2015-2024
- Share of malaria cases in Latin America 2022, by country
- Malaria cases in Venezuela 2010-2022
- Malaria cases in Brazil 2010-2022
- Malaria cases in Colombia 2010-2022
- Zika virus cases in Latin America 2023, by country
- Zika virus cases in Guatemala 2015-2023
- Zika virus infections in Paraguay 2015-2023
- Prevalence of 15 neglected tropical diseases worldwide from 1990 to 2020
- Prevalence of 15 neglected tropical diseases worldwide in 2020, by region
- Countries with largest number of people requiring action against NTDs worldwide 2022
- Prevalence of 15 neglected tropical diseases in Latin America 1990-2020
- Prevalence of 15 neglected tropical diseases in Latin America 2020, by country
Other statistics that may interest you Tropical diseases in Latin America
Health care overview
- Premium Statistic Healthcare spending in Latin America and the Caribbean 2020, by country
- Premium Statistic Healthcare spending per capita in Latin America and the Caribbean 2020, by country
- Basic Statistic GHS Index robust health system in Latin America 2021
- Premium Statistic Health care quality in selected Latin American countries 2023
- Premium Statistic Availability of health care information in Latin America 2023
Risk factors
- Premium Statistic Flooding risk index in Latin America & the Caribbean 2023, by country
- Premium Statistic Epidemic risk index in Latin America & the Caribbean 2023, by country
- Premium Statistic Vector-borne disease risk index in Latin America & the Caribbean 2023, by country
- Basic Statistic People living in poverty and extreme poverty in Latin America 1990-2022
- Premium Statistic Latin America: food insecurity prevalence 2014-2022, by severity
Chikungunya
- Premium Statistic Chikungunya cases in Latin America 2015-2023
- Premium Statistic Chikungunya cases in Latin America 2023, by country
- Premium Statistic Chikungunya cases in Brazil 2015-2023
- Premium Statistic Chikungunya cases in Paraguay 2014-2023
- Premium Statistic Chikungunya cases in Guatemala 2014-2023
- Basic Statistic Dengue cases in Latin America & the Caribbean 2016-2024
- Basic Statistic Dengue cases in Latin America & the Caribbean 2024, by country
- Premium Statistic Dengue cases in Brazil 2015-2024
- Premium Statistic Dengue cases in Nicaragua 2015-2024
- Premium Statistic Dengue cases in Peru 2015-2024
- Premium Statistic Countries with most malaria cases in Latin America 2022
- Premium Statistic Share of malaria cases in Latin America 2022, by country
- Premium Statistic Malaria cases in Venezuela 2010-2022
- Premium Statistic Malaria cases in Brazil 2010-2022
- Premium Statistic Malaria cases in Colombia 2010-2022
- Premium Statistic Zika virus cases in Latin America 2015-2023
- Premium Statistic Zika virus cases in Latin America 2023, by country
- Premium Statistic Zika virus cases in Brazil 2015-2023
- Premium Statistic Zika virus cases in Guatemala 2015-2023
- Premium Statistic Zika virus infections in Paraguay 2015-2023
Neglected tropical diseases
- Basic Statistic Prevalence of 15 neglected tropical diseases worldwide from 1990 to 2020
- Premium Statistic Prevalence of 15 neglected tropical diseases worldwide in 2020, by region
- Basic Statistic Countries with largest number of people requiring action against NTDs worldwide 2022
- Basic Statistic Prevalence of 15 neglected tropical diseases in Latin America 1990-2020
- Basic Statistic Prevalence of 15 neglected tropical diseases in Latin America 2020, by country
Further Content: You might find this interesting as well
Got any suggestions?
We want to hear from you! Send us a message and help improve Slidesgo
Top searches
Trending searches
26 templates
6 templates
first day of school
69 templates
environmental science
37 templates
49 templates
12 templates
International Malaria Day
It seems that you like this template, international malaria day presentation, free google slides theme, powerpoint template, and canva presentation template.
Malaria is a disease, often fatal, transmitted by parasites that reach humans through the bite of the female Anopheles mosquito. However, despite its seriousness, it is a preventable and curable condition. Hence the importance of International Malaria Day, a date that serves to raise awareness that the fight to prevent this disease must be constant. Now you can talk about this international day with this creative template that is full of very visual illustrations that will catch the attention of everyone who sees your presentation.
Features of this template
- 100% editable and easy to modify
- 35 different slides to impress your audience
- Contains easy-to-edit graphics such as graphs, maps, tables, timelines and mockups
- Includes 500+ icons and Flaticon’s extension for customizing your slides
- Designed to be used in Google Slides, Canva, and Microsoft PowerPoint
- 16:9 widescreen format suitable for all types of screens
- Includes information about fonts, colors, and credits of the resources used
How can I use the template?
Am I free to use the templates?
How to attribute?
Attribution required If you are a free user, you must attribute Slidesgo by keeping the slide where the credits appear. How to attribute?
Related posts on our blog.
How to Add, Duplicate, Move, Delete or Hide Slides in Google Slides
How to Change Layouts in PowerPoint
How to Change the Slide Size in Google Slides
Related presentations.
Premium template
Unlock this template and gain unlimited access
IMAGES
COMMENTS
Malaria is a life-threatening disease caused by parasites that are transmitted to people through the bites of infected female mosquitoes. About 3.2 billion people - almost half of the world's population - are at risk of malaria. Young children, pregnant women and non-immune travelers from malaria-free areas are particularly vulnerable to ...
Free Google Slides theme, PowerPoint template, and Canva presentation template. If you want to explain some details about malaria, use this medical presentation. Provide some explanations about its diagnosis, recommendations, pathology, treatments and conclusions. It's very creative and full of cartoons.
Whether the presentation is dedicated to medical professionals or an informative presentation, this simple but effective template will help you. The cream-toned, decorated slides of malaria-transmitting mosquitoes (those infected by the Plasmodium parasite) are full of resources to organize your content. And if you need help, read the included ...
Clinical characteristics of locally acquired mosquito- transmitted malaria —U.S., May-July 2023. • All 8 individuals were adults and had fever • 7/8 (88%) individuals were hospitalized • All 8 individuals received oral antimalarial treatment -All received treatment to prevent future disease relapse -All have recovered.
3. CDC Operational Research Priorities in 2010. From Scale-up To Elimination. Optimize current malaria control interventions. Establish role for new and revisited interventions. Research and development. Clinical and field trials of new interventions. Integration with other initiatives.
1. Reduce malaria mortality rates globally compared with 2015 >40% >75% >90% 2. Reduce malaria case incidence globally compared with 2015 >40% >75% >90% 3. Eliminate malaria from countries in which malaria was transmitted in 2015 At least 10 countries At least 20 countries At least 35 countries 4. Prevent re-establishment of malaria in all ...
ppt/slides/slide71.xmläVmO#7 þ^©ÿÁÚïaó !º€H€ö$Ê!'»ïÆëM,¼¶±½K¢Sÿ{Ç/› ½iOU¿ìÚ û™™Ç3žùtº(8ª¨6LŠaÒ:h&ˆ "3&fÃäëô²ÑO ±Xd˜KA‡É'šäôä×_>© á ‚Ó ð0™ ...
Overview. Malaria is a life-threatening disease spread to humans by some types of mosquitoes. It is mostly found in tropical countries. It is preventable and curable. The infection is caused by a parasite and does not spread from person to person. Symptoms can be mild or life-threatening. Mild symptoms are fever, chills and headache.
Malaria is a treatable disease. Artemisinin-based combination therapies (ACTs) are the most effective antimalarial medicines available today and the mainstay of recommended treatment for Plasmodium falciparum malaria, the deadliest malaria parasite globally. ACTs combine 2 active pharmaceuticals with different mechanisms of action, including derivates of artemisinin extracted from the plant ...
GuestLecture5Oct-Malaria.ppt. WHAT IS MALARIA? • An infective disease caused by protozoan parasites that are transmitted through the bite of an infected Anopheles mosquito; marked by paroxysms of chills and fever. MALARIA FACTS.
MALARIA. -Research scientists have been trying to develop an effective vaccine for more than 50 years. -Malaria is cause by a one-celled organism called Plasmodium. -Some symptoms of malaria isfever and flu-like illness, including shaking chills, headache, muscle aches, and tiredness. Nausea, vomiting,diarrhea ,and may cause anemia.
This year (2022), the Malaria Champions Committee has reviewed the initiative to better respond to current and future challenges, taking into account the new Malaria Elimination Action Plan 2021-2025. The need to promote more sustained actions, stimulate greater diversity of champions and greater appropriation by different actors in the countries, as well as promote improvements in the use of ...
Free Google Slides theme, PowerPoint template, and Canva presentation template. Malaria is a disease transmitted by the bite of an infected mosquito and causes about 800,000 deaths per year, especially in Africa. World Malaria Day, which takes place on April 25, was created to raise awareness. If you need to create a presentation to help you ...
Malaria powerpoint slides FINAL. Malaria powerpoint slides FINAL_5.2.2015.pptx.
+ •e+w eWW ëôqÿ] CqßÔÕ"HRl×Y# ó ¿ps®aüª^†.ëŒ=ÍLLŸ "—±F Ò4 ½,†ÿ"— ˆ¬' 8 T >!Y /3?× p¸ü¦7ð rÀû ¼¯Í Ðujz1‰Hè…Á µÁ6 § 0~Ù" x üqoz\¦˜ÈÌ × ®g ;ìû ÿÿ PK !g[ ¡l ppt/slides/slide13.xmlÌUÛnÛ8 }/Ð ô®è~3ê -l -ºÛ N?€¡è˜¨$ $ãÚ(úï R" Û y\?ˆcr†3sÎ ...
In malaria endemic areas, people may develop partial immunity, allowing asymptomatic infections to occur. Some population groups are at considerably higher risk of contracting malaria, and developing severe disease, than others. These include infants, children under 5 years of age, pregnant women and patients with HIV/AIDS, as well as non ...
Headache and muscle aches. Fatigue. Chest pain, breathing problems and cough. Diarrhea, nausea and vomiting. As malaria gets worse, it can cause anemia and jaundice (yellowing of the skin and whites of the eyes). The most severe form of malaria, which may progress to a coma, is known as cerebral malaria.
Causal Agent. Blood parasites of the genus Plasmodium.There are approximately 156 named species of Plasmodium which infect various species of vertebrates. Four species are considered true parasites of humans, as they utilize humans almost exclusively as a natural intermediate host: P. falciparum, P. vivax, P. ovale and P. malariae.However, there are periodic reports of simian malaria parasites ...
• Mosquito nets: long lasting insecticide treated bed nets to create a protective barrier from mosquitos. • Targeted insecticide spraying: sprayed on the walls in order to kill mosquitos which helps reduce the rate of malaria. • Government funding: Can keep the malaria death to
CrystalGraphics creates templates designed to make even average presentations look incredible. Below you'll see thumbnail sized previews of the title slides of a few of our 20 best malaria templates for PowerPoint and Google Slides. The text you'll see in in those slides is just example text. The malaria-related image or video you'll see ...
Connie Helensa 2017730139 FK UNIVERSITAS MUHAMMADIYAH JAKARTA 2017-CEMPAKA PUTIH MALARIA MALARIA GEJALA GEJALA A. Badan terasa lemas dan pucat karena kekurangan darah dan berkeringat. B. Nafsu makan menurun. C.Mual-mual kadang-kadang diikuti muntah. D. Sakit kepala yang berat,
Free Google Slides theme and PowerPoint template. Download the "Malaria Case Study" presentation for PowerPoint or Google Slides. A clinical case is more than just a set of symptoms and a diagnosis. It is a unique story of a patient, their experiences, and their journey towards healing. Each case is an opportunity for healthcare professionals ...
The population estimated to be at risk of contracting malaria in Honduras fluctuated between 17.1 and 90.9 percent during the period analyzed. In the last year depicted, 24.3 percent of the ...
Free Google Slides theme, PowerPoint template, and Canva presentation template. Malaria is a disease, often fatal, transmitted by parasites that reach humans through the bite of the female Anopheles mosquito. However, despite its seriousness, it is a preventable and curable condition. Hence the importance of International Malaria Day, a date ...