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How to Publish a Research Paper: A Step-by-Step Guide

Jordan Kruszynski

January 4, 2024

You’re in academia.

You’re going steady.

Your research is going well and you begin to wonder: ‘ How exactly do I get a research paper published?’

If this is the question on your lips, then this step-by-step guide is the one for you. We’ll be walking you through the whole process of how to publish a research paper.

Publishing a research paper is a significant milestone for researchers and academics, as it allows you to share your findings, contribute to your field of study, and start to gain serious recognition within the wider academic community. So, want to know how to publish a research paper? By following our guide, you’ll get a firm grasp of the steps involved in this process, giving you the best chance of successfully navigating the publishing process and getting your work out there.

Understanding the Publishing Process

To begin, it’s crucial to understand that getting a research paper published is a multi-step process. From beginning to end, it could take as little as 2 months before you see your paper nestled in the pages of your chosen journal. On the other hand, it could take as long as a year .

Below, we set out the steps before going into more detail on each one. Getting a feel for these steps will help you to visualise what lies ahead, and prepare yourself for each of them in turn. It’s important to remember that you won’t actually have control over every step – in fact, some of them will be decided by people you’ll probably never meet. However, knowing which parts of the process are yours to decide will allow you to adjust your approach and attitude accordingly.

Each of the following stages will play a vital role in the eventual publication of your paper:

Preparing Your Research Paper
Finding the Right Journal
Crafting a Strong Manuscript
Navigating the Peer-Review Process
Submitting Your Paper
Dealing with Rejections and Revising Your Paper

Step 1: Preparing Your Research Paper

It all starts here. The quality and content of your research paper is of fundamental importance if you want to get it published. This step will be different for every researcher depending on the nature of your research, but if you haven’t yet settled on a topic, then consider the following advice:

Choose an interesting and relevant topic that aligns with current trends in your field. If your research touches on the passions and concerns of your academic peers or wider society, it may be more likely to capture attention and get published successfully.
Conduct a comprehensive literature review (link to lit. review article once it’s published) to identify the state of existing research and any knowledge gaps within it. Aiming to fill a clear gap in the knowledge of your field is a great way to increase the practicality of your research and improve its chances of getting published.
Structure your paper in a clear and organised manner, including all the necessary sections such as title, abstract, introduction (link to the ‘how to write a research paper intro’ article once it’s published) , methodology, results, discussion, and conclusion.
Adhere to the formatting guidelines provided by your target journal to ensure that your paper is accepted as viable for publishing. More on this in the next section…

Step 2: Finding the Right Journal

Understanding how to publish a research paper involves selecting the appropriate journal for your work. This step is critical for successful publication, and you should take several factors into account when deciding which journal to apply for:

Conduct thorough research to identify journals that specialise in your field of study and have published similar research. Naturally, if you submit a piece of research in molecular genetics to a journal that specialises in geology, you won’t be likely to get very far.
Consider factors such as the journal’s scope, impact factor, and target audience. Today there is a wide array of journals to choose from, including traditional and respected print journals, as well as numerous online, open-access endeavours. Some, like Nature , even straddle both worlds.
Review the submission guidelines provided by the journal and ensure your paper meets all the formatting requirements and word limits. This step is key. Nature, for example, offers a highly informative series of pages that tells you everything you need to know in order to satisfy their formatting guidelines (plus more on the whole submission process).
Note that these guidelines can differ dramatically from journal to journal, and details really do matter. You might submit an outstanding piece of research, but if it includes, for example, images in the wrong size or format, this could mean a lengthy delay to getting it published. If you get everything right first time, you’ll save yourself a lot of time and trouble, as well as strengthen your publishing chances in the first place.

Step 3: Crafting a Strong Manuscript

Crafting a strong manuscript is crucial to impress journal editors and reviewers. Look at your paper as a complete package, and ensure that all the sections tie together to deliver your findings with clarity and precision.

Begin by creating a clear and concise title that accurately reflects the content of your paper.
Compose an informative abstract that summarises the purpose, methodology, results, and significance of your study.
Craft an engaging introduction (link to the research paper introduction article) that draws your reader in.
Develop a well-structured methodology section, presenting your results effectively using tables and figures.
Write a compelling discussion and conclusion that emphasise the significance of your findings.

Step 4: Navigating the Peer-Review Process

Once you submit your research paper to a journal, it undergoes a rigorous peer-review process to ensure its quality and validity. In peer-review, experts in your field assess your research and provide feedback and suggestions for improvement, ultimately determining whether your paper is eligible for publishing or not. You are likely to encounter several models of peer-review, based on which party – author, reviewer, or both – remains anonymous throughout the process.

When your paper undergoes the peer-review process, be prepared for constructive criticism and address the comments you receive from your reviewer thoughtfully, providing clear and concise responses to their concerns or suggestions. These could make all the difference when it comes to making your next submission.

The peer-review process can seem like a closed book at times. Check out our discussion of the issue with philosopher and academic Amna Whiston in The Research Beat podcast!

Step 5: Submitting Your Paper

As we’ve already pointed out, one of the key elements in how to publish a research paper is ensuring that you meticulously follow the journal’s submission guidelines. Strive to comply with all formatting requirements, including citation styles, font, margins, and reference structure.

Before the final submission, thoroughly proofread your paper for errors, including grammar, spelling, and any inconsistencies in your data or analysis. At this stage, consider seeking feedback from colleagues or mentors to further improve the quality of your paper.

Step 6: Dealing with Rejections and Revising Your Paper

Rejection is a common part of the publishing process, but it shouldn’t discourage you. Analyse reviewer comments objectively and focus on the constructive feedback provided. Make necessary revisions and improvements to your paper to address the concerns raised by reviewers. If needed, consider submitting your paper to a different journal that is a better fit for your research.

For more tips on how to publish your paper out there, check out this thread by Dr. Asad Naveed ( @dr_asadnaveed ) – and if you need a refresher on the basics of how to publish under the Open Access model, watch this 5-minute video from Audemic Academy !

Final Thoughts

Successfully understanding how to publish a research paper requires dedication, attention to detail, and a systematic approach. By following the advice in our guide, you can increase your chances of navigating the publishing process effectively and achieving your goal of publication.

Remember, the journey may involve revisions, peer feedback, and potential rejections, but each step is an opportunity for growth and improvement. Stay persistent, maintain a positive mindset, and continue to refine your research paper until it reaches the standards of your target journal. Your contribution to your wider discipline through published research will not only advance your career, but also add to the growing body of collective knowledge in your field. Embrace the challenges and rewards that come with the publication process, and may your research paper make a significant impact in your area of study!

Looking for inspiration for your next big paper? Head to Audemic , where you can organise and listen to all the best and latest research in your field!

Keep striving, researchers! ✨

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Research Papers

How to Write and Publish Your Research in a Journal

Last Updated: February 26, 2024 Fact Checked

Choosing a Journal

Writing the research paper, editing & revising your paper, submitting your paper, navigating the peer review process, research paper help.

This article was co-authored by Matthew Snipp, PhD and by wikiHow staff writer, Cheyenne Main . C. Matthew Snipp is the Burnet C. and Mildred Finley Wohlford Professor of Humanities and Sciences in the Department of Sociology at Stanford University. He is also the Director for the Institute for Research in the Social Science’s Secure Data Center. He has been a Research Fellow at the U.S. Bureau of the Census and a Fellow at the Center for Advanced Study in the Behavioral Sciences. He has published 3 books and over 70 articles and book chapters on demography, economic development, poverty and unemployment. He is also currently serving on the National Institute of Child Health and Development’s Population Science Subcommittee. He holds a Ph.D. in Sociology from the University of Wisconsin—Madison. There are 13 references cited in this article, which can be found at the bottom of the page. This article has been fact-checked, ensuring the accuracy of any cited facts and confirming the authority of its sources. This article has been viewed 699,234 times.

Publishing a research paper in a peer-reviewed journal allows you to network with other scholars, get your name and work into circulation, and further refine your ideas and research. Before submitting your paper, make sure it reflects all the work you’ve done and have several people read over it and make comments. Keep reading to learn how you can choose a journal, prepare your work for publication, submit it, and revise it after you get a response back.

Things You Should Know

Create a list of journals you’d like to publish your work in and choose one that best aligns with your topic and your desired audience.
Prepare your manuscript using the journal’s requirements and ask at least 2 professors or supervisors to review your paper.
Write a cover letter that “sells” your manuscript, says how your research adds to your field and explains why you chose the specific journal you’re submitting to.

Step 1 Create a list of journals you’d like to publish your work in.

Ask your professors or supervisors for well-respected journals that they’ve had good experiences publishing with and that they read regularly.
Many journals also only accept specific formats, so by choosing a journal before you start, you can write your article to their specifications and increase your chances of being accepted.
If you’ve already written a paper you’d like to publish, consider whether your research directly relates to a hot topic or area of research in the journals you’re looking into.

Step 2 Look at each journal’s audience, exposure, policies, and procedures.

Review the journal’s peer review policies and submission process to see if you’re comfortable creating or adjusting your work according to their standards.
Open-access journals can increase your readership because anyone can access them.

Step 1 Craft an effective introduction with a thesis statement.

Scientific research papers: Instead of a “thesis,” you might write a “research objective” instead. This is where you state the purpose of your research.
“This paper explores how George Washington’s experiences as a young officer may have shaped his views during difficult circumstances as a commanding officer.”
“This paper contends that George Washington’s experiences as a young officer on the 1750s Pennsylvania frontier directly impacted his relationship with his Continental Army troops during the harsh winter at Valley Forge.”

Step 2 Write the literature review and the body of your paper.

Scientific research papers: Include a “materials and methods” section with the step-by-step process you followed and the materials you used. [5] X Research source
Read other research papers in your field to see how they’re written. Their format, writing style, subject matter, and vocabulary can help guide your own paper. [6] X Research source

Step 3 Write your conclusion that ties back to your thesis or research objective.

If you’re writing about George Washington’s experiences as a young officer, you might emphasize how this research changes our perspective of the first president of the U.S.
Link this section to your thesis or research objective.
If you’re writing a paper about ADHD, you might discuss other applications for your research.

Step 4 Write an abstract that describes what your paper is about.

Scientific research papers: You might include your research and/or analytical methods, your main findings or results, and the significance or implications of your research.
Try to get as many people as you can to read over your abstract and provide feedback before you submit your paper to a journal.

Step 1 Prepare your manuscript according to the journal’s requirements.

They might also provide templates to help you structure your manuscript according to their specific guidelines. [11] X Research source

Step 2 Ask 2 colleagues to review your paper and revise it with their notes.

Not all journal reviewers will be experts on your specific topic, so a non-expert “outsider’s perspective” can be valuable.

Step 1 Check your sources for plagiarism and identify 5 to 6 keywords.

If you have a paper on the purification of wastewater with fungi, you might use both the words “fungi” and “mushrooms.”
Use software like iThenticate, Turnitin, or PlagScan to check for similarities between the submitted article and published material available online. [15] X Research source

Step 2 Write a cover letter explaining why you chose their journal.

Header: Address the editor who will be reviewing your manuscript by their name, include the date of submission, and the journal you are submitting to.
First paragraph: Include the title of your manuscript, the type of paper it is (like review, research, or case study), and the research question you wanted to answer and why.
Second paragraph: Explain what was done in your research, your main findings, and why they are significant to your field.
Third paragraph: Explain why the journal’s readers would be interested in your work and why your results are important to your field.
Conclusion: State the author(s) and any journal requirements that your work complies with (like ethical standards”).
“We confirm that this manuscript has not been published elsewhere and is not under consideration by another journal.”
“All authors have approved the manuscript and agree with its submission to [insert the name of the target journal].”

Step 3 Submit your article according to the journal’s submission guidelines.

Submit your article to only one journal at a time.
When submitting online, use your university email account. This connects you with a scholarly institution, which can add credibility to your work.

Step 1 Try not to panic when you get the journal’s initial response.

Accept: Only minor adjustments are needed, based on the provided feedback by the reviewers. A first submission will rarely be accepted without any changes needed.
Revise and Resubmit: Changes are needed before publication can be considered, but the journal is still very interested in your work.
Reject and Resubmit: Extensive revisions are needed. Your work may not be acceptable for this journal, but they might also accept it if significant changes are made.
Reject: The paper isn’t and won’t be suitable for this publication, but that doesn’t mean it might not work for another journal.

Step 2 Revise your paper based on the reviewers’ feedback.

Try organizing the reviewer comments by how easy it is to address them. That way, you can break your revisions down into more manageable parts.
If you disagree with a comment made by a reviewer, try to provide an evidence-based explanation when you resubmit your paper.

Step 3 Resubmit to the same journal or choose another from your list.

If you’re resubmitting your paper to the same journal, include a point-by-point response paper that talks about how you addressed all of the reviewers’ comments in your revision. [22] X Research source
If you’re not sure which journal to submit to next, you might be able to ask the journal editor which publications they recommend.

Expert Q&A

About This Article

To publish a research paper, ask a colleague or professor to review your paper and give you feedback. Once you've revised your work, familiarize yourself with different academic journals so that you can choose the publication that best suits your paper. Make sure to look at the "Author's Guide" so you can format your paper according to the guidelines for that publication. Then, submit your paper and don't get discouraged if it is not accepted right away. You may need to revise your paper and try again. To learn about the different responses you might get from journals, see our reviewer's explanation below. Did this summary help you? Yes No

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How to Write and Publish a Research Paper in 7 Steps

What comes next after you're done with your research? Publishing the results in a journal of course! We tell you how to present your work in the best way possible.

This post is part of a series, which serves to provide hands-on information and resources for authors and editors.

Things have gotten busy in scholarly publishing: These days, a new article gets published in the 50,000 most important peer-reviewed journals every few seconds, while each one takes on average 40 minutes to read. Hundreds of thousands of papers reach the desks of editors and reviewers worldwide each year and 50% of all submissions end up rejected at some stage.

In a nutshell: there is a lot of competition, and the people who decide upon the fate of your manuscript are short on time and overworked. But there are ways to make their lives a little easier and improve your own chances of getting your work published!

Well, it may seem obvious, but before submitting an academic paper, always make sure that it is an excellent reflection of the research you have done and that you present it in the most professional way possible. Incomplete or poorly presented manuscripts can create a great deal of frustration and annoyance for editors who probably won’t even bother wasting the time of the reviewers!

This post will discuss 7 steps to the successful publication of your research paper:

Check whether your research is publication-ready
Choose an article type
Choose a journal
Construct your paper
Decide the order of authors
Check and double-check
Submit your paper

1. Check Whether Your Research Is Publication-Ready

Should you publish your research at all?

If your work holds academic value – of course – a well-written scholarly article could open doors to your research community. However, if you are not yet sure, whether your research is ready for publication, here are some key questions to ask yourself depending on your field of expertise:

Have you done or found something new and interesting? Something unique?
Is the work directly related to a current hot topic?
Have you checked the latest results or research in the field?
Have you provided solutions to any difficult problems?
Have the findings been verified?
Have the appropriate controls been performed if required?
Are your findings comprehensive?

If the answers to all relevant questions are “yes”, you need to prepare a good, strong manuscript. Remember, a research paper is only useful if it is clearly understood, reproducible and if it is read and used .

2. Choose An Article Type

The first step is to determine which type of paper is most appropriate for your work and what you want to achieve. The following list contains the most important, usually peer-reviewed article types in the natural sciences:

Full original research papers disseminate completed research findings. On average this type of paper is 8-10 pages long, contains five figures, and 25-30 references. Full original research papers are an important part of the process when developing your career.

Review papers present a critical synthesis of a specific research topic. These papers are usually much longer than original papers and will contain numerous references. More often than not, they will be commissioned by journal editors. Reviews present an excellent way to solidify your research career.

Letters, Rapid or Short Communications are often published for the quick and early communication of significant and original advances. They are much shorter than full articles and usually limited in length by the journal. Journals specifically dedicated to short communications or letters are also published in some fields. In these the authors can present short preliminary findings before developing a full-length paper.

3. Choose a Journal

Are you looking for the right place to publish your paper? Find out here whether a De Gruyter journal might be the right fit.

Submit to journals that you already read, that you have a good feel for. If you do so, you will have a better appreciation of both its culture and the requirements of the editors and reviewers.

Other factors to consider are:

The specific subject area
The aims and scope of the journal
The type of manuscript you have written
The significance of your work
The reputation of the journal
The reputation of the editors within the community
The editorial/review and production speeds of the journal
The community served by the journal
The coverage and distribution
The accessibility ( open access vs. closed access)

4. Construct Your Paper

Each element of a paper has its purpose, so you should make these sections easy to index and search.

Don’t forget that requirements can differ highly per publication, so always make sure to apply a journal’s specific instructions – or guide – for authors to your manuscript, even to the first draft (text layout, paper citation, nomenclature, figures and table, etc.) It will save you time, and the editor’s.

Also, even in these days of Internet-based publishing, space is still at a premium, so be as concise as possible. As a good journalist would say: “Never use three words when one will do!”

Let’s look at the typical structure of a full research paper, but bear in mind certain subject disciplines may have their own specific requirements so check the instructions for authors on the journal’s home page.

4.1 The Title

It’s important to use the title to tell the reader what your paper is all about! You want to attract their attention, a bit like a newspaper headline does. Be specific and to the point. Keep it informative and concise, and avoid jargon and abbreviations (unless they are universally recognized like DNA, for example).

4.2 The Abstract

This could be termed as the “advertisement” for your article. Make it interesting and easily understood without the reader having to read the whole article. Be accurate and specific, and keep it as brief and concise as possible. Some journals (particularly in the medical fields) will ask you to structure the abstract in distinct, labeled sections, which makes it even more accessible.

A clear abstract will influence whether or not your work is considered and whether an editor should invest more time on it or send it for review.

4.3 Keywords

Keywords are used by abstracting and indexing services, such as PubMed and Web of Science. They are the labels of your manuscript, which make it “searchable” online by other researchers.

Include words or phrases (usually 4-8) that are closely related to your topic but not “too niche” for anyone to find them. Make sure to only use established abbreviations. Think about what scientific terms and its variations your potential readers are likely to use and search for. You can also do a test run of your selected keywords in one of the common academic search engines. Do similar articles to your own appear? Yes? Then that’s a good sign.

4.4 Introduction

This first part of the main text should introduce the problem, as well as any existing solutions you are aware of and the main limitations. Also, state what you hope to achieve with your research.

Do not confuse the introduction with the results, discussion or conclusion.

4.5 Methods

Every research article should include a detailed Methods section (also referred to as “Materials and Methods”) to provide the reader with enough information to be able to judge whether the study is valid and reproducible.

Include detailed information so that a knowledgeable reader can reproduce the experiment. However, use references and supplementary materials to indicate previously published procedures.

4.6 Results

In this section, you will present the essential or primary results of your study. To display them in a comprehensible way, you should use subheadings as well as illustrations such as figures, graphs, tables and photos, as appropriate.

4.7 Discussion

Here you should tell your readers what the results mean .

Do state how the results relate to the study’s aims and hypotheses and how the findings relate to those of other studies. Explain all possible interpretations of your findings and the study’s limitations.

Do not make “grand statements” that are not supported by the data. Also, do not introduce any new results or terms. Moreover, do not ignore work that conflicts or disagrees with your findings. Instead …

Be brave! Address conflicting study results and convince the reader you are the one who is correct.

4.8 Conclusion

Your conclusion isn’t just a summary of what you’ve already written. It should take your paper one step further and answer any unresolved questions.

Sum up what you have shown in your study and indicate possible applications and extensions. The main question your conclusion should answer is: What do my results mean for the research field and my community?

4.9 Acknowledgments and Ethical Statements

It is extremely important to acknowledge anyone who has helped you with your paper, including researchers who supplied materials or reagents (e.g. vectors or antibodies); and anyone who helped with the writing or English, or offered critical comments about the content.

Learn more about academic integrity in our blog post “Scholarly Publication Ethics: 4 Common Mistakes You Want To Avoid” .

Remember to state why people have been acknowledged and ask their permission . Ensure that you acknowledge sources of funding, including any grant or reference numbers.

Furthermore, if you have worked with animals or humans, you need to include information about the ethical approval of your study and, if applicable, whether informed consent was given. Also, state whether you have any competing interests regarding the study (e.g. because of financial or personal relationships.)

4.10 References

The end is in sight, but don’t relax just yet!

De facto, there are often more mistakes in the references than in any other part of the manuscript. It is also one of the most annoying and time-consuming problems for editors.

Remember to cite the main scientific publications on which your work is based. But do not inflate the manuscript with too many references. Avoid excessive – and especially unnecessary – self-citations. Also, avoid excessive citations of publications from the same institute or region.

5. Decide the Order of Authors

In the sciences, the most common way to order the names of the authors is by relative contribution.

Generally, the first author conducts and/or supervises the data analysis and the proper presentation and interpretation of the results. They put the paper together and usually submit the paper to the journal.

Co-authors make intellectual contributions to the data analysis and contribute to data interpretation. They review each paper draft. All of them must be able to present the paper and its results, as well as to defend the implications and discuss study limitations.

Do not leave out authors who should be included or add “gift authors”, i.e. authors who did not contribute significantly.

6. Check and Double-Check

As a final step before submission, ask colleagues to read your work and be constructively critical .

Make sure that the paper is appropriate for the journal – take a last look at their aims and scope. Check if all of the requirements in the instructions for authors are met.

Ensure that the cited literature is balanced. Are the aims, purpose and significance of the results clear?

Conduct a final check for language, either by a native English speaker or an editing service.

7. Submit Your Paper

When you and your co-authors have double-, triple-, quadruple-checked the manuscript: submit it via e-mail or online submission system. Along with your manuscript, submit a cover letter, which highlights the reasons why your paper would appeal to the journal and which ensures that you have received approval of all authors for submission.

It is up to the editors and the peer-reviewers now to provide you with their (ideally constructive and helpful) comments and feedback. Time to take a breather!

If the paper gets rejected, do not despair – it happens to literally everybody. If the journal suggests major or minor revisions, take the chance to provide a thorough response and make improvements as you see fit. If the paper gets accepted, congrats!

It’s now time to get writing and share your hard work – good luck!

If you are interested, check out this related blog post

[Title Image by Nick Morrison via Unsplash]

David Sleeman

David Sleeman worked as Senior Journals Manager in the field of Physical Sciences at De Gruyter.

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Understanding the Publishing Process

What’s happening with my paper? The publication process explained

The path to publication can be unsettling when you’re unsure what’s happening with your paper. Learn about staple journal workflows to see the detailed steps required for ensuring a rigorous and ethical publication.

Your team has prepared the paper, written a cover letter and completed the submission form. From here, it can sometimes feel like a waiting game while the journal has your paper. It can be unclear exactly who is currently handling your paper as most individuals are only involved in a few steps of the overall process. Journals are responsible for overseeing the peer review, publication and archival process: editors, reviewers, technical editors, production staff and other internal staff all have their roles in ensuring submissions meet rigorous scientific and ethical reporting standards.

Read on for an inside look at how a conventional peer-reviewed journal helps authors transform their initial submission to a certified publication.

Note that the description below is based on the process at PLOS journals. It is likely that at other journals, various roles (e.g. technical editor) may in fact also be played by the editor, and some journals may not have journal staff at all, with all roles played by volunteer academics. As such, please consider the processes and waypoints, rather than who performs them, as the key information.

Internal Checks on New Submissions

Estimated time: 10 days.

When a journal first receives your submission, there are typically two separate checks to confirm that the paper is appropriate and ready for peer review:

Technical check. Performed by a technical editor to ensure that the submission has been properly completed and is ready for further assessment. Blurry figures, missing ethical statements, and incomplete author affiliations are common issues that are addressed at this initial stage. Typically, there are three technical checks: upon initial submission, alongside the first decision letter, and upon acceptance.
Editorial screening . Once a paper passes the first check, an editor with subject expertise assesses the paper and determines whether it is within the journal’s scope and if it could potentially meet the required publication criteria. While there may be requests for further information and minor edits from the author as needed, the paper will either be desk rejected by the editor or allowed to proceed to peer review.

Both editors at this point will additionally make notes for items to be followed-up on at later stages. The publication process involves finding a careful balance for when each check occurs. Early checks need to be thorough so that editors with relevant expertise can focus on the scientific content and more advanced reporting standards, but no one wants to be asked to reformat references only to have their paper desk rejected a few days later.

Peer Review

Estimated time: 1 month.

Depending on the journal’s editorial structure, the editor who performed the initial assessment may also oversee peer review or another editor with more specific expertise may be assigned. Regardless of the journal’s specific process, the various roles and responsibilities during peer review include:

When you have questions or are unsure who your manuscripts is currently with, reach out to the journal staff for help (eg. [email protected]). They will be your lifeline, connecting you to all the other contributors working to assess the manuscript.

Whether an editor needs a reminder that all reviews are complete or a reviewer has asked for an extension, the journal acts as a central hub of communication for those involved with the publication process. As editors and reviewers are used to hearing from journal staff about their duties, any messages you send to the journal can be forwarded to them with proper context and instructions on how to proceed appropriately. Additionally, journal staff will be able to inform you of any delays, such as reviewer availability during summer and holiday periods.

Revision Decision

Estimated time: 1 day.

Editors evaluate peer reviewer feedback and their own expert assessment of the manuscript to reach a decision. After your editor submits a decision on your manuscript, the journal may review it before formally processing the decision and sending it on to you.

A technical editor may scan the manuscript and the review comments to ensure that journal standards have been followed. At this stage, the technical editor will also add requests to ensure the paper, if published, will adhere to journal requirements for data sharing, copyright, ethical reporting and the like.

Performing the second technical check at this stage and adding the journal requirements to the decision letter ultimately saves time by allowing authors to resolve the journal’s queries while making revisions based on comments from the reviewers.

Revised Submission Received

Estimated time: 3 days.

Upon receiving your revised submission, a technical editor will assess the revisions to confirm that the requests from the journal have been properly addressed. Before the paper is returned to the editor for their consideration, the journal needs to be confident that the paper won’t have any issues related to the metadata and reporting standards that could prevent publication. The editor may contact you to resolve any serious issues, though minor items can wait until the paper is accepted.

Subsequent Peer Review

Estimated time: 2 weeks, highly variable.

When your resubmitted paper has passed the required checks, it’ll be assigned back to the same editor who handled it during the first round of peer review. At this point, your paper has gone through two sets of journal checks and one round of peer review. If all has gone well so far, the paper should feel quite solid both in terms of scientific content and proper reporting standards.

When the editor receives your revised paper, they are asked to check if all reviewer comments have been adequately addressed and if the paper now adheres to the journal’s publication criteria. Depending on the situation, some editors may feel confident making this decision based on their own expertise while others may re-invite the previous reviewers for their opinions.

Individual responsibilities are the same as the initial round of peer review, but it is generally expected that later stages of peer review proceed quicker unless new concerns have been introduced as part of the revision.

Preliminary Acceptance

Estimated time: 1 week.

Your editor is satisfied with the scientific quality of your work and has chosen to accept it in principle. Before it can proceed to production and typesetting, the journal office will perform it’s third and final technical check, requesting any formatting changes or additional details that may be required.

When fulfilling these final journal requests, double check the final files to confirm all information is correct. If you need to make changes beyond those specifically required in the decision letter, inform the journal and explain why you made the unrequested changes. Any change that could affect the scientific meaning of the work will need to be approved by the handling editor. While including your rationale for the changes will help avoid delays, if there are extensive changes made at this point the paper may need to go through another round of formal review.

Formal Acceptance and Publication

Estimated time: 2 weeks.

After a technical editor has confirmed that all requests from the provisional acceptance letter have been addressed, you will receive your formal acceptance letter. This letter indicates that your paper is being passed from the Editorial department to the production department—that all information has been editorially approved. The scientific content has been approved through peer review, and the journal’s publication requirements have been met.

Congratulations to you and your co-authors! Your article will be available as soon as the journal transforms the submission into a typeset, consistently structured scientific manuscript, ready to be read and cited by your peers.

The contents of the Peer Review Center are also available as a live, interactive training session, complete with slides, talking points, and activities. …

The contents of the Writing Center are also available as a live, interactive training session, complete with slides, talking points, and activities. …

There’s a lot to consider when deciding where to submit your work. Learn how to choose a journal that will help your study reach its audience, while reflecting your values as a researcher…

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How to publish a scientific paper: writing the paper.

Writing the paper
Submitting the manuscript
Editorial process
Maximizing impact

Image (detail): Subhashish Panigrahi, Wikimedia Commons , CC-BY-SA 4.0

Writing a scientific paper

Before you begin.

Review the literature: Ensure that the research question has not been investigated before and that the experimental methods are appropriate. Librarians can help!
Research data management (UC Berkeley): Ensure that your data meet disciplinary guidelines, and that you will be able to comply with funder and journal policies for data deposit and sharing.

Quick writing guides

11 steps to structuring a science paper editors will take seriously (Borja 2014, updated 2021)
The Science of Science Writing (Gopen and Swan 1990)
Short Guide to Scientific Writing (Sawyer n.d.)
Ten simple principles for structuring papers (Mensh and Kording 2017)
Writing workshop program PLOS Neglected Tropical Diseases, 2015; includes general as well as journal-specific guidelines. General guidelines begin at slide 13.

Image (detail): istock/Thomas Shanahan ( Elsevier Connect )

In-depth writing guides and resources

Nature Masterclass on Scientific Writing and Publishing Requires creating free Nature account, accessing from Berkeley IP address or using the Berkeley VPN with Library Access - Full Tunnel gateway, and enabling popups.
How to Write a Good Scientific Paper (Mack 2018)
Writing science: how to write papers that get cited and proposals that get funded (Schimel 2012)
Graduate Writing Center (UC Berkeley)

Image (detail): Nature Masterclasses

Reporting guidelines

Digital Curation Centre (DCC): https://www.dcc.ac.uk/guidance/standards/metadata
Enhancing the QUAlity and Transparency Of health Research (EQUATOR): https://www.equator-network.org/reporting-guidelines/ for human- and animal-subjects research
FAIRsharing: https://fairsharing.org/standards/

Writing tools

Manage your citations : Citation managers EndNote, Mendeley, RefWorks, and Zotero (UC Berkeley Library guide)

Writing + Citing in the Sciences : LaTeX editor Overleaf and citation managers (UC Berkeley Library guide)

LaTeX in Engineering & Physical Sciences : The document formatting markup language LaTeX, which is especially useful for rendering mathematical and chemical symbols and equations (UC Berkeley Library guide)
Virtual Online Library Tutorials (VOLT): LaTeX : Self-paced exercises for learning LaTeX

For more help

Writing tips & tools

Writing tips.

Avoid fragmentation (breaking a single study into multiple short papers) and redundant publication (submitting multiple papers that are very similar).

When writing a scientific paper, think about the structure familiar to you from reading scientific papers. A common structure for scientific research articles is termed IMRAD: Introduction, Methods, Results, And Discussion. A fuller outline is provided below:

Title: most important element; include standard, searchable terms (keywords) to call attention to your work. Articles with short titles describing the results are cited more often (Paiva et al. 2012); cited 200 times (Google Scholar)
What is the problem domain (system under investigation)?
What is the specific research question ?
What were the methods and results ?
What are the conclusions ?
Introduction: describes the general problem domain (system under investigation) and then focuses on the specific research question addressed and/or the hypothesis tested by this paper.
Methods and materials: provides enough detail to enable experiment to be reproduced by another researcher in your field. Standard experimental methods can be indicated by a reference to a published protocol. Some journals have adopted STAR Methods (Structured, Transparent, Accessible Reporting), which includes a Key Resources Table listing all reagents, antibodies, cell lines, software, or other resources required for the experiment. Use of identifiers such as Research Resource Identifiers (RRIDs) is strongly encouraged. Protocols can be shared publicly or privately on protocols.io . If they are original they can be published in a protocol journal such as bio-protocol , STAR protocols , or JoVE .
Figures: clear and compelling; each figure should tell a single story: Data Visualization Guide (UC Berkeley Library)
Discussion: explains meaning and significance of results (how do they advance the field?) and how they relate to the research question; describes limitations and further work suggested by study.
Data availability statement: Some publishers require a statement describing how the data can be accessed and reused, or the data protection concerns (such as privacy or commercial sensitivity) that prevent sharing.
Acknowledgements: Unless there are separate sections for this information, name funding sources , declare any potential competing interests , and thank contributors who are not co-authors. For human- and animal-subject research, an ethics statement may be required identifying the review committee that approved the study and the relevant guidelines and regulations that governed the research.
References : A list of sources cited in your paper. Citations (both in-text and in the reference list) must be accurate and formatted in the journal's required style. Use a citation manager .
Supplementary information : supporting technical information (figures, protocols, methods, tables, additional data) too long or detailed to fit into the body of the paper.

General tips:

first focus on the results (including figures and tables ), discussion and methods (communicating the experimental outcomes, significance and procedures)
then work on the introduction , abstract and title (increasingly concise summaries of the work).
Use simple, concrete, active language ("We determined..." not "It was determined that...")
Start paragraphs with a topic sentence
Consider your audience: narrowly specialized or interdisciplinary ?
Be as clear and concise as possible
Next: Submitting the manuscript >>
Last Updated: Jan 30, 2024 2:39 PM
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StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-.

StatPearls [Internet].

How to write and publish a scientific manuscript.

Martin R. Huecker ; Jacob Shreffler .

Affiliations

Last Update: October 31, 2022 .

Definition/Introduction

A clinician should continuously strive to increase knowledge by reviewing and critiquing papers, thoughtfully considering how to integrate new data into practice. This is the essence of evidence-based medicine (EBM). [1] When new clinical queries arise, one should seek answers in the published literature. The ability to read a scientific or medical manuscript remains vitally important throughout the career of a clinician.

When gaps exist in the literature, clinicians should consider conducting their own research into these questions. Though typically performed by academic doctors or physician-scientists, medical research is open to all clinicians in both informal and formal methods. Anyone who treats patients can collect data on outcomes to assess the quality of care delivered (quality improvement is research). [2] Though beyond the scope of this chapter, instruction for clinicians on how to conduct research and contribute to medical science is provided by many resources. [3] [4] [5]

Additionally, a clinician who integrates a new practice can study effects on patient outcomes, retro- or prospectively. Continuous practice improvement need not be shared with the larger population of treating providers, but dissemination to the entire scientific community allows widespread adoption, criticism, or further testing for replication of findings.

Issues of Concern

Clinicians who seek to conduct retrospective chart reviews, prospective studies, or even randomized, controlled clinical trials should access the many resources to ensure quality methodology. [5] Once you have followed the appropriate steps to conduct a study (Table 1), you should complete the process by writing a manuscript to describe your findings and share it with other clinicians and researchers. Other resources detail the steps in undertaking writing a review article, but this StatPearls chapter will focus on Writing a Scientific Manuscript for original research. See also the StatPearls chapter for the different types of research manuscripts. [6]

Clinical Significance

Steps to Conducting Research

Develop a research question
Perform a literature search
Identify a gap in the literature
Design a study protocol (including personnel)
Submit to an institutional review board for approval
Collect, responsibly store, and then analyze data
Write a manuscript to interpret and describe your research.

After conducting a quality investigation or a study, one should put together an abstract and manuscript to share results. Researchers can write an abstract in a short amount of time, though the abstract will evolve as the full manuscript moves to completion. Many published and presented abstracts do not reach full manuscript publication. [7] [8] Although journals and conferences do often publish abstracts, studies with important results should be published in full manuscript form to ensure dissemination and allow attempts at replication. [9]

IRB protocols, study design, and data collection and aggregation require a team effort. Those involved in the research should discuss who will contribute to the full manuscript (i.e., qualify as an author) and thus the planned order of authorship to reduce complications at the time of manuscript submission. The author, who devotes the most effort to the paper, is typically the first and corresponding author. In contrast, the last author is often the most senior member of the team, often the principal investigator of the study. All individuals listed as authors should contribute to the manuscript and overall project in some fashion. [10]

The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) checklist is perhaps the most valuable tool in the process of preparing your manuscript for submission [11] .

Original research manuscripts have the following sections (in chronologic order): [11]

Title and Abstract

Introduction (Background and Objectives)

Methods (Design, Setting, Participants, Variables, Statistics)

Results (Participants, Descriptives, Outcomes, Subgroups)

Tables and Figures

Discussion (Key findings, Limitations, Interpretations)

Conflict of Interest (COI), Author affiliations, Acknowledgments, Funding

Individuals involved in the IRB submission (prior to data collection) can write the introduction and methods of the manuscript before and during the process of data collection and analysis. This head start on writing makes the full manuscript composition task less formidable. The content of the introduction and methods should be well known to the study group prior to data collection and analysis. The introduction should be organized into a “problem/gap/hook” order: what problem does this study address, the precise gap in the literature, and the objectives of this study (in addressing the gap). [12] The methods should provide enough detail such that readers who would like to replicate the study could do so.

Once data is collected and analyzed, authors can write an abstract to organize major themes of the research, understanding that the abstract will undergo edits once the manuscript is complete. Similarly, the title can change with revisions, as authors determine the most salient trends in the data. Most readers will only read the title +/- abstract. Thus these are the most important sections of the paper. The title should be concise and should directly describe the results of the trial– this correlates with more citations. The abstract must convey the crucial findings of the paper, ideally divided into sections for easier reading (unless the desired journal does not allow this). [13]

With the larger picture in mind, authors should create tables and figures that visually convey the themes of the data analysis. Working with statisticians or data experts, authors should devote a great deal of time to this component of the manuscript. Some general concepts: [14]

Only include tables/figures that you believe are necessary.
Make sure tables/figures are of high quality, simple, clear, with concise captions.
Do not repeat language in results that appear in tables/figures, i.e., the tables/figures should stand alone.
Consider how the figure will look in grayscale (in case the journal if not in color)

As with the abstract and title, the tables and figures will likely undergo further edits prior to the completion of the manuscript. The abstract and tables/figures should intuitively evolve together to convey the ‘story’ of the research project.

At this point, refer back to the introduction and methods composed during data collection. Make revisions as necessary to reflect the overall narrative of the project. Ensure you have adhered to the originally determined objectives or hypotheses.

Next, focus on the results and discussion. The results should contain only objective data with no interpretation of significance. Describe salient results than do not already receive explanations within the figures and tables. The discussion section begins with a lead paragraph highlighting the most important findings from the study. Then the discussion interprets the current results in light of prior published literature. Ensure citation of keystone papers on this topic, including new papers that have been published since embarking on the current project. Frame your results, describing how this study adds to the literature. The discussion section usually includes study limitations. Attempt to anticipate criticisms of the methodology, the results, the organization of the manuscript itself, and the (ability to draw) conclusions. A stronger limitations section preempts journal reviewer feedback, potentially simplifying the revision/resubmission process.

The conclusion section should be concise, conveying the main take-home points from your study. You can make recommendations for current clinical practice and for future research endeavors. Finally, consider using citation management software such as Endnote or Mendeley. Though initially cumbersome, these software platforms drastically improve revision efforts and allow for easy reference reformatting. All authors should review the manuscript multiple times, potentially sharing with other uninvolved colleagues for objective feedback. Consider who should receive acknowledgment for supporting the project and prepare to disclose conflicts of interest and funding.

Although authors should have an initial idea of which journal to submit to, once the manuscript is near completion, this decision will be more straightforward. Journal rankings are beyond the scope of this StatPearls chapter. Still, generally, one should devise a list of the journals within a specialty in order of highest to lowest impact factor (some sites categorize into tiers). High-quality prospective research and clinical trials have a higher likelihood of acceptance into the more prestigious journals within a specialty or to the high-quality general science or medicine journals. Although many journals have an option for open access publication, and numerous legitimate, open access journals now exist, beware of ‘predatory journals’ that charge a fee to publish and may not be indexed in Pubmed or other databases. [12]

Journals have diverse guidelines for formatting and submission, and the manuscript submission process can be tedious. Prior to submission, review Bordage’s paper on reasons for manuscript rejection. [15] Most journals require a title page and cover letter, the latter of which represents an opportunity to lobby for your paper’s importance. When (not if) you experience manuscript rejections, take reviewer comments and recommendations seriously. Use this valuable feedback for resubmission to the original journal (when invited) or for subsequent submission to other journals. When submitting a requested revision, compose a point by point response to the reviewers and attach a new manuscript with tracked changes. Attempt to resubmit manuscripts as promptly as possible, keeping your work in the hands of journals (allowing you to work on other research). [14]

Nursing, Allied Health, and Interprofessional Team Interventions

The above logistic steps will differ for review articles, case reports, editorials, and other types of submissions. [16] However, the organization, precise methods, and adherence to journal guidelines remain important. See work by Provenzale on principles to increase the likelihood of acceptance for original and revised manuscripts. After submission, revision, resubmission, and proofing, you may experience the fulfillment of an official publication. Academics should promote their scientific work, enhancing the dissemination of research to the wider scientific community. [17] [18] [17] [19]

Review Questions
Access free multiple choice questions on this topic.
Comment on this article.

Disclosure: Martin Huecker declares no relevant financial relationships with ineligible companies.

Disclosure: Jacob Shreffler declares no relevant financial relationships with ineligible companies.

This book is distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) ( http://creativecommons.org/licenses/by-nc-nd/4.0/ ), which permits others to distribute the work, provided that the article is not altered or used commercially. You are not required to obtain permission to distribute this article, provided that you credit the author and journal.

Cite this Page Huecker MR, Shreffler J. How To Write And Publish A Scientific Manuscript. [Updated 2022 Oct 31]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-.

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How to write a research paper

Last updated

11 January 2024

Reviewed by

With proper planning, knowledge, and framework, completing a research paper can be a fulfilling and exciting experience.

Though it might initially sound slightly intimidating, this guide will help you embrace the challenge.

By documenting your findings, you can inspire others and make a difference in your field. Here's how you can make your research paper unique and comprehensive.

What is a research paper?

Research papers allow you to demonstrate your knowledge and understanding of a particular topic. These papers are usually lengthier and more detailed than typical essays, requiring deeper insight into the chosen topic.

To write a research paper, you must first choose a topic that interests you and is relevant to the field of study. Once you’ve selected your topic, gathering as many relevant resources as possible, including books, scholarly articles, credible websites, and other academic materials, is essential. You must then read and analyze these sources, summarizing their key points and identifying gaps in the current research.

You can formulate your ideas and opinions once you thoroughly understand the existing research. To get there might involve conducting original research, gathering data, or analyzing existing data sets. It could also involve presenting an original argument or interpretation of the existing research.

Writing a successful research paper involves presenting your findings clearly and engagingly, which might involve using charts, graphs, or other visual aids to present your data and using concise language to explain your findings. You must also ensure your paper adheres to relevant academic formatting guidelines, including proper citations and references.

Overall, writing a research paper requires a significant amount of time, effort, and attention to detail. However, it is also an enriching experience that allows you to delve deeply into a subject that interests you and contribute to the existing body of knowledge in your chosen field.

How long should a research paper be?

Research papers are deep dives into a topic. Therefore, they tend to be longer pieces of work than essays or opinion pieces.

However, a suitable length depends on the complexity of the topic and your level of expertise. For instance, are you a first-year college student or an experienced professional?

Also, remember that the best research papers provide valuable information for the benefit of others. Therefore, the quality of information matters most, not necessarily the length. Being concise is valuable.

Following these best practice steps will help keep your process simple and productive:

1. Gaining a deep understanding of any expectations

Before diving into your intended topic or beginning the research phase, take some time to orient yourself. Suppose there’s a specific topic assigned to you. In that case, it’s essential to deeply understand the question and organize your planning and approach in response. Pay attention to the key requirements and ensure you align your writing accordingly.

This preparation step entails

Deeply understanding the task or assignment

Being clear about the expected format and length

Familiarizing yourself with the citation and referencing requirements

Understanding any defined limits for your research contribution

Where applicable, speaking to your professor or research supervisor for further clarification

2. Choose your research topic

Select a research topic that aligns with both your interests and available resources. Ideally, focus on a field where you possess significant experience and analytical skills. In crafting your research paper, it's crucial to go beyond summarizing existing data and contribute fresh insights to the chosen area.

Consider narrowing your focus to a specific aspect of the topic. For example, if exploring the link between technology and mental health, delve into how social media use during the pandemic impacts the well-being of college students. Conducting interviews and surveys with students could provide firsthand data and unique perspectives, adding substantial value to the existing knowledge.

When finalizing your topic, adhere to legal and ethical norms in the relevant area (this ensures the integrity of your research, protects participants' rights, upholds intellectual property standards, and ensures transparency and accountability). Following these principles not only maintains the credibility of your work but also builds trust within your academic or professional community.

For instance, in writing about medical research, consider legal and ethical norms , including patient confidentiality laws and informed consent requirements. Similarly, if analyzing user data on social media platforms, be mindful of data privacy regulations, ensuring compliance with laws governing personal information collection and use. Aligning with legal and ethical standards not only avoids potential issues but also underscores the responsible conduct of your research.

3. Gather preliminary research

Once you’ve landed on your topic, it’s time to explore it further. You’ll want to discover more about available resources and existing research relevant to your assignment at this stage.

This exploratory phase is vital as you may discover issues with your original idea or realize you have insufficient resources to explore the topic effectively. This key bit of groundwork allows you to redirect your research topic in a different, more feasible, or more relevant direction if necessary.

Spending ample time at this stage ensures you gather everything you need, learn as much as you can about the topic, and discover gaps where the topic has yet to be sufficiently covered, offering an opportunity to research it further.

4. Define your research question

To produce a well-structured and focused paper, it is imperative to formulate a clear and precise research question that will guide your work. Your research question must be informed by the existing literature and tailored to the scope and objectives of your project. By refining your focus, you can produce a thoughtful and engaging paper that effectively communicates your ideas to your readers.

5. Write a thesis statement

A thesis statement is a one-to-two-sentence summary of your research paper's main argument or direction. It serves as an overall guide to summarize the overall intent of the research paper for you and anyone wanting to know more about the research.

A strong thesis statement is:

Concise and clear: Explain your case in simple sentences (avoid covering multiple ideas). It might help to think of this section as an elevator pitch.

Specific: Ensure that there is no ambiguity in your statement and that your summary covers the points argued in the paper.

Debatable: A thesis statement puts forward a specific argument––it is not merely a statement but a debatable point that can be analyzed and discussed.

Here are three thesis statement examples from different disciplines:

Psychology thesis example: "We're studying adults aged 25-40 to see if taking short breaks for mindfulness can help with stress. Our goal is to find practical ways to manage anxiety better."

Environmental science thesis example: "This research paper looks into how having more city parks might make the air cleaner and keep people healthier. I want to find out if more green spaces means breathing fewer carcinogens in big cities."

UX research thesis example: "This study focuses on improving mobile banking for older adults using ethnographic research, eye-tracking analysis, and interactive prototyping. We investigate the usefulness of eye-tracking analysis with older individuals, aiming to spark debate and offer fresh perspectives on UX design and digital inclusivity for the aging population."

6. Conduct in-depth research

A research paper doesn’t just include research that you’ve uncovered from other papers and studies but your fresh insights, too. You will seek to become an expert on your topic––understanding the nuances in the current leading theories. You will analyze existing research and add your thinking and discoveries. It's crucial to conduct well-designed research that is rigorous, robust, and based on reliable sources. Suppose a research paper lacks evidence or is biased. In that case, it won't benefit the academic community or the general public. Therefore, examining the topic thoroughly and furthering its understanding through high-quality research is essential. That usually means conducting new research. Depending on the area under investigation, you may conduct surveys, interviews, diary studies , or observational research to uncover new insights or bolster current claims.

7. Determine supporting evidence

Not every piece of research you’ve discovered will be relevant to your research paper. It’s important to categorize the most meaningful evidence to include alongside your discoveries. It's important to include evidence that doesn't support your claims to avoid exclusion bias and ensure a fair research paper.

8. Write a research paper outline

Before diving in and writing the whole paper, start with an outline. It will help you to see if more research is needed, and it will provide a framework by which to write a more compelling paper. Your supervisor may even request an outline to approve before beginning to write the first draft of the full paper. An outline will include your topic, thesis statement, key headings, short summaries of the research, and your arguments.

9. Write your first draft

Once you feel confident about your outline and sources, it’s time to write your first draft. While penning a long piece of content can be intimidating, if you’ve laid the groundwork, you will have a structure to help you move steadily through each section. To keep up motivation and inspiration, it’s often best to keep the pace quick. Stopping for long periods can interrupt your flow and make jumping back in harder than writing when things are fresh in your mind.

10. Cite your sources correctly

It's always a good practice to give credit where it's due, and the same goes for citing any works that have influenced your paper. Building your arguments on credible references adds value and authenticity to your research. In the formatting guidelines section, you’ll find an overview of different citation styles (MLA, CMOS, or APA), which will help you meet any publishing or academic requirements and strengthen your paper's credibility. It is essential to follow the guidelines provided by your school or the publication you are submitting to ensure the accuracy and relevance of your citations.

11. Ensure your work is original

It is crucial to ensure the originality of your paper, as plagiarism can lead to serious consequences. To avoid plagiarism, you should use proper paraphrasing and quoting techniques. Paraphrasing is rewriting a text in your own words while maintaining the original meaning. Quoting involves directly citing the source. Giving credit to the original author or source is essential whenever you borrow their ideas or words. You can also use plagiarism detection tools such as Scribbr or Grammarly to check the originality of your paper. These tools compare your draft writing to a vast database of online sources. If you find any accidental plagiarism, you should correct it immediately by rephrasing or citing the source.

12. Revise, edit, and proofread

One of the essential qualities of excellent writers is their ability to understand the importance of editing and proofreading. Even though it's tempting to call it a day once you've finished your writing, editing your work can significantly improve its quality. It's natural to overlook the weaker areas when you've just finished writing a paper. Therefore, it's best to take a break of a day or two, or even up to a week, to refresh your mind. This way, you can return to your work with a new perspective. After some breathing room, you can spot any inconsistencies, spelling and grammar errors, typos, or missing citations and correct them.

The best research paper format

The format of your research paper should align with the requirements set forth by your college, school, or target publication.

There is no one “best” format, per se. Depending on the stated requirements, you may need to include the following elements:

Title page: The title page of a research paper typically includes the title, author's name, and institutional affiliation and may include additional information such as a course name or instructor's name.

Table of contents: Include a table of contents to make it easy for readers to find specific sections of your paper.

Abstract: The abstract is a summary of the purpose of the paper.

Methods : In this section, describe the research methods used. This may include collecting data , conducting interviews, or doing field research .

Results: Summarize the conclusions you drew from your research in this section.

Discussion: In this section, discuss the implications of your research . Be sure to mention any significant limitations to your approach and suggest areas for further research.

Tables, charts, and illustrations: Use tables, charts, and illustrations to help convey your research findings and make them easier to understand.

Works cited or reference page: Include a works cited or reference page to give credit to the sources that you used to conduct your research.

Bibliography: Provide a list of all the sources you consulted while conducting your research.

Dedication and acknowledgments : Optionally, you may include a dedication and acknowledgments section to thank individuals who helped you with your research.

General style and formatting guidelines

Formatting your research paper means you can submit it to your college, journal, or other publications in compliance with their criteria.

Research papers tend to follow the American Psychological Association (APA), Modern Language Association (MLA), or Chicago Manual of Style (CMOS) guidelines.

Here’s how each style guide is typically used:

Chicago Manual of Style (CMOS):

CMOS is a versatile style guide used for various types of writing. It's known for its flexibility and use in the humanities. CMOS provides guidelines for citations, formatting, and overall writing style. It allows for both footnotes and in-text citations, giving writers options based on their preferences or publication requirements.

American Psychological Association (APA):

APA is common in the social sciences. It’s hailed for its clarity and emphasis on precision. It has specific rules for citing sources, creating references, and formatting papers. APA style uses in-text citations with an accompanying reference list. It's designed to convey information efficiently and is widely used in academic and scientific writing.

Modern Language Association (MLA):

MLA is widely used in the humanities, especially literature and language studies. It emphasizes the author-page format for in-text citations and provides guidelines for creating a "Works Cited" page. MLA is known for its focus on the author's name and the literary works cited. It’s frequently used in disciplines that prioritize literary analysis and critical thinking.

To confirm you're using the latest style guide, check the official website or publisher's site for updates, consult academic resources, and verify the guide's publication date. Online platforms and educational resources may also provide summaries and alerts about any revisions or additions to the style guide.

Citing sources

When working on your research paper, it's important to cite the sources you used properly. Your citation style will guide you through this process. Generally, there are three parts to citing sources in your research paper:

First, provide a brief citation in the body of your essay. This is also known as a parenthetical or in-text citation.

Second, include a full citation in the Reference list at the end of your paper. Different types of citations include in-text citations, footnotes, and reference lists.

In-text citations include the author's surname and the date of the citation.

Footnotes appear at the bottom of each page of your research paper. They may also be summarized within a reference list at the end of the paper.

A reference list includes all of the research used within the paper at the end of the document. It should include the author, date, paper title, and publisher listed in the order that aligns with your citation style.

10 research paper writing tips:

Following some best practices is essential to writing a research paper that contributes to your field of study and creates a positive impact.

These tactics will help you structure your argument effectively and ensure your work benefits others:

Clear and precise language: Ensure your language is unambiguous. Use academic language appropriately, but keep it simple. Also, provide clear takeaways for your audience.

Effective idea separation: Organize the vast amount of information and sources in your paper with paragraphs and titles. Create easily digestible sections for your readers to navigate through.

Compelling intro: Craft an engaging introduction that captures your reader's interest. Hook your audience and motivate them to continue reading.

Thorough revision and editing: Take the time to review and edit your paper comprehensively. Use tools like Grammarly to detect and correct small, overlooked errors.

Thesis precision: Develop a clear and concise thesis statement that guides your paper. Ensure that your thesis aligns with your research's overall purpose and contribution.

Logical flow of ideas: Maintain a logical progression throughout the paper. Use transitions effectively to connect different sections and maintain coherence.

Critical evaluation of sources: Evaluate and critically assess the relevance and reliability of your sources. Ensure that your research is based on credible and up-to-date information.

Thematic consistency: Maintain a consistent theme throughout the paper. Ensure that all sections contribute cohesively to the overall argument.

Relevant supporting evidence: Provide concise and relevant evidence to support your arguments. Avoid unnecessary details that may distract from the main points.

Embrace counterarguments: Acknowledge and address opposing views to strengthen your position. Show that you have considered alternative arguments in your field.

7 research tips

If you want your paper to not only be well-written but also contribute to the progress of human knowledge, consider these tips to take your paper to the next level:

Selecting the appropriate topic: The topic you select should align with your area of expertise, comply with the requirements of your project, and have sufficient resources for a comprehensive investigation.

Use academic databases: Academic databases such as PubMed, Google Scholar, and JSTOR offer a wealth of research papers that can help you discover everything you need to know about your chosen topic.

Critically evaluate sources: It is important not to accept research findings at face value. Instead, it is crucial to critically analyze the information to avoid jumping to conclusions or overlooking important details. A well-written research paper requires a critical analysis with thorough reasoning to support claims.

Diversify your sources: Expand your research horizons by exploring a variety of sources beyond the standard databases. Utilize books, conference proceedings, and interviews to gather diverse perspectives and enrich your understanding of the topic.

Take detailed notes: Detailed note-taking is crucial during research and can help you form the outline and body of your paper.

Stay up on trends: Keep abreast of the latest developments in your field by regularly checking for recent publications. Subscribe to newsletters, follow relevant journals, and attend conferences to stay informed about emerging trends and advancements.

Engage in peer review: Seek feedback from peers or mentors to ensure the rigor and validity of your research . Peer review helps identify potential weaknesses in your methodology and strengthens the overall credibility of your findings.

The real-world impact of research papers

Writing a research paper is more than an academic or business exercise. The experience provides an opportunity to explore a subject in-depth, broaden one's understanding, and arrive at meaningful conclusions. With careful planning, dedication, and hard work, writing a research paper can be a fulfilling and enriching experience contributing to advancing knowledge.

How do I publish my research paper?

Many academics wish to publish their research papers. While challenging, your paper might get traction if it covers new and well-written information. To publish your research paper, find a target publication, thoroughly read their guidelines, format your paper accordingly, and send it to them per their instructions. You may need to include a cover letter, too. After submission, your paper may be peer-reviewed by experts to assess its legitimacy, quality, originality, and methodology. Following review, you will be informed by the publication whether they have accepted or rejected your paper.

What is a good opening sentence for a research paper?

Beginning your research paper with a compelling introduction can ensure readers are interested in going further. A relevant quote, a compelling statistic, or a bold argument can start the paper and hook your reader. Remember, though, that the most important aspect of a research paper is the quality of the information––not necessarily your ability to storytell, so ensure anything you write aligns with your goals.

Research paper vs. a research proposal—what’s the difference?

While some may confuse research papers and proposals, they are different documents.

A research proposal comes before a research paper. It is a detailed document that outlines an intended area of exploration. It includes the research topic, methodology, timeline, sources, and potential conclusions. Research proposals are often required when seeking approval to conduct research.

A research paper is a summary of research findings. A research paper follows a structured format to present those findings and construct an argument or conclusion.

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How to Write & Publish a Research Paper: Step-by-Step Guide

This guide is far more than a list of instructions on what to include in each section of your research paper. In fact, we will:

Use a research paper I wrote specifically as an example to illustrate the key ideas in this guide ( link to the full-text PDF of the research paper ).
Use real-world data (on 100,000 PubMed research papers) to show you how professional scientists write in practice, instead of presenting my own opinion on the subject.
Provide practical tips on how to: improve your writing , find the right journal , and submit your article .

Let’s get started!

Structure of a research paper
Writing the Introduction section
Writing the Methods section
Writing the Results section
Writing the Discussion section
Writing the Abstract
Writing the Title
Writing optional sections
Refining and improving your article
Managing and formatting your References
Submitting your article

1. Structure of a research paper

Most research papers follow the IMRaD structure that consists of 4 main sections:

I ntroduction
D iscussion

The paper also has some essential elements–Title, Abstract, and References–and may contain other optional sections–Conclusion, Acknowledgements, Funding, Conflicts of interest, and Appendix.

These sections often appear in the following order:

The advantages of following the IMRaD structure are:

To make the paper easily scannable by readers (since most won’t read the entire manuscript.
To avoid repeating the same information in different places.

To follow the IMRaD structure, you must learn what information goes where.

So, here’s an overview of what each of the main sections represents:

Together, these 4 sections start with the main topic of the paper and end up with a conclusion regarding that topic:

Role of each of the main sections of a research paper

1.1. Where to start?

When writing a research paper, some people prefer to start with the Results section—since it comes out right from the data they just analyzed. Others start with the Methods section—since information about how they designed the study and analyzed the data is still fresh in their mind. Personally, I prefer to start with the Introduction section for 2 reasons:

While doing a literature review for the introduction, sometimes I discover a problem in my approach or an interesting secondary objective that I did not think about, which as you can imagine, changes a lot of things in other sections of the article.
I want to formulate the hypothesis before analyzing the data in order to avoid HARKing (Hypothesizing after the results are known) which is a major problem in statistics (see: 7 Tricks to Get Statistically Significant p-Values ).

2. Writing the Introduction section

The Introduction targets a non-specialized audience, so when writing it, make sure to use simple and beginner-friendly terms.

2.1. Length of the Introduction section

The introduction section should be:

400 to 760 words long (3 to 5 paragraphs).
The shortest section of the article (half the length of the other sections: Methods, Results, and Discussion).

(These data are based on an analysis I made on 61,518 articles from PubMed )

2.2. Structure of the Introduction section

Here’s what you should include in the Introduction:

Step #1: Describe the general context of your work (your aim should be to convince the reader that the topic of your research is interesting).
Step #2: Summarize the results of previous studies on the topic (report what others have found and provide references. But don’t do an in-depth literature review, a short summary of these findings is enough).
Step #3: Identify the gap , problem, or limitations of previous studies (find the missing pieces of the puzzle).
Step #4: State your objective , hypothesis, question that you want to answer, or problem that you want to solve (make sure that the purpose of your study is clear and understandable, otherwise people won’t care about your results).
Step #5: Present your solution : explain the approach you used to achieve the objective, explain what is different about it and what makes it special. Here you have to sell your approach. But keep it short (leave the details to the methods section).

2.3. Verb tense and voice in the Introduction section

Use the past tense for things that were already done and the present tense for things that continue to be true today.

For instance:

“Previous studies found that the rate of heart disease is increasing “.

“The goal of this study is to explore why the rate of heart disease increased in the past 10 years”.

You should write the Introduction using mainly the active voice.

“ A recent study found conflicting results”.

Should be favored over:

“ Conflicting results were recently found “.

2.4. Example: writing an Introduction section

In this section, we are going to verify that the Introduction section of our example article ( link to the full-text PDF ) follows the step-by-step structure discussed above. (The article studies the influence of title length on its attractiveness).

What follows is the Introduction of that article with the main steps highlighted:

INTRODUCTION

The role of a research title is to draw the reader’s attention while providing an overview of the article’s content. Finding a way to engage readers is important since only 18% of those who read the title proceed to read the abstract (Mabe and Amin, 2002).

Title attractiveness may be affected by its length; but studies on this subject have been inconsistent and sometimes contradictory (Subotic and Mukherjee, 2014; Letchford et al., 2015; Guo et al., 2018; Jacques and Sebire, 2010; Habibzadeh and Yadollahie, 2010; Stremersch et al., 2007; Falahati Qadimi Fumani et al., 2015). This may be due to bias and confounding since these studies did not follow a causal model to eliminate alternative explanations and indirect effects.

The confusion over the effect of title length led to a gap between what professional writers recommend and what researchers do in practice: while professionals recommend keeping titles as short as possible (Zeiger, 1999; Neill, 2007), in practice, titles are getting longer (Milojevi¢, 2017; Whissell, 2012) and more descriptive (mentioning the study objective, the variables involved, the main result, and the study design).

To help resolve this issue, the present study aims to quantify the direct influence of title length on its attractiveness by analyzing data on 9,830 biomedical research papers from PubMed and adjusting for confounding and indirect effects through the use of a causal diagram.

Writing is not just about following a series of rules: you should keep an eye on the flow of your story that ties your paragraphs together.

Here’s an overview of the story of our Introduction section:

Mains ideas in our example introduction section

3. Writing the Methods section

The Methods section is the recipe for the study: it should provide enough information to replicate the study without looking elsewhere (although most of those who read the Methods section will not be interested in replicating your study, instead they just want to make sure that your study is credible).

The Methods is the most technical section of the article. So, unlike the Introduction, don’t shy away from technical terms, since those who are not interested in such details will most likely skip this section.

3.1. Length of the Methods section

The Methods section should be:

760 to 1,620 words long (6 to 14 paragraphs).
The same length as the Results or the Discussion, and about double the length of the Introduction.

(These data are based on an analysis I did on 61,514 articles from PubMed )

3.2. Structure of the Methods section

Here’s what you should include in the Methods section:

The date and duration of the study.
The sampling procedure.
The assignment to different study groups.
The source of the data.
Any approval needed to conduct the study.
Step#3: List the inclusion and exclusion criteria (i.e., the characteristics that participants must have to be included in the study).
The reason behind choosing such procedure.
The order in which things were done (a flow diagram can simplify the description of complex procedures).
The calculation of the minimum sample size needed.
The role of each variable (dependent, independent, or control variable).
The methods used to address bias in the study.
The methods used to handle missing data.
The measures used to summarize the data.
The type of statistical test or model you used to test your hypothesis and the threshold for statistical significance (don’t go into detail about obvious statistical tests or models, but advanced methods should be either described or referenced).
The statistical software used [optional].

3.3. Verb tense and voice in the Methods section

Use the past tense (because the things you did took place in the past).

“The data were downloaded “.

“A linear regression model was used “.

Use the passive voice (to avoid repeating the pronouns: “I” or “We”).

“Variables were summarized using the mean and standard deviation”.

Instead of:

“I summarized the variables using the mean and standard deviation”.

3.4. Example: writing a Methods section

In this section, we are going to verify that the Methods section of our example article ( link to the full-text P D F ) follows the structure discussed above. (Remember that this article is about studying the influence of title length on its attractiveness).

What follows is the Methods section of this article with the main steps highlighted:

For this cross-sectional study, data were downloaded from PubMed Central in March 2021 using a web API created by Comeau et al. (2019). From a collection of about 3 million biomedical research articles from various journals, 105,984 were chosen at random from those uploaded between the years 2016 and 2021.

From these 105,984 articles, a total of 96,154 were discarded for incomplete data, leaving 9,830 articles ready for analysis (Figure 4). Reasons for discarding articles included: unavailable full text, unmentioned study design, missing impact factor of the journal in which the article was published, missing article DOI, and unavailable citation count.

To study the influence of title length on its attractiveness, and in order to avoid defining and measuring Title attractiveness , I substituted this variable with another closely related one: the Citation count for a given article; this can work provided that we block all alternative paths other than the direct effect of Title attractiveness on Citation count . Looking at the causal diagram in Figure 5, we notice that there is only one alternative path, and it can be blocked by adjusting for the Journal in which the article was published. Since the data contained articles from 1,040 different journals (and to avoid complicating the analysis by creating 1,039 dummy variables), I ended up adjusting for the Journal impact factor , a direct descendent of the deconfounding variable Journal , thus representing most of its effect.

Example of a figure format in a research paper

To compute the direct causal effect of Title length on Title attractiveness , alternative explanations of the association between these two such as confounding and indirect effects must also be eliminated. From Figure 5, we see that this can be accomplished by adjusting for the Mention of study design in the title (a confounder) and the use of Comma in the title and Colon in the title (indirect effects).

After determining the variables that we want to adjust for, Poisson regression was used to compute the effect of Title length on Citation count . In our case, a Poisson model has 2 major advantages over linear regression: (1) it fits the data better, since counts follow a Poisson rather than a normal distribution, and (2) it accounts for different publication dates of different articles, which is important to offset the advantage of older articles regarding the time they had to collect citations (this can be accomplished by including Years since publication as an offset in the model).

The Poisson model described above can be summarized with the following equation:

log(Citation count) =β 0 + β 1 × Title length + β 2 × Journal impact factor + β 3 × Mention of study design in the title + β 4 × Comma in the title + β 5 × Colon in the title + log(Years since publication)

Variables in the model, such as Citation count , Title length , and Journal impact factor , were summarized using the median and the interquartile range (IQR), since they follow either a Poisson or a skewed non-normal distribution.

Note that in some cases, you will be forced to include some results in the Methods section. Although the research paper has a separate Results section (which we will discuss next), sometimes we include some results in the Methods section to justify the use of a certain material or method.

For example, in the Methods section above, in order to defend the use of the variable Journal impact factor instead of Journal , I ended up reporting the number of journals in the study (which is a number calculated from the data, so it normally belongs to the Results section):

“Since the data contained articles from 1,040 different journals (and to avoid complicating the analysis by creating 1,039 dummy variables), I ended up adjusting for the Journal impact factor, a direct descendent of the deconfounding variable Journal, thus representing most of its effect.”

4. Writing the Results section

In the Results section, you should describe and summarize your findings without explaining them (the interpretation should be left for the Discussion section).

4.1. Length of the Results section

The Results section should be:

610 to 1,660 words long (5 to 11 paragraphs).
The same length as the Methods or the Discussion, and about double the length of the Introduction.

(These data are based on an analysis I did on 61,458 articles from PubMed )

4.2. Structure of the Results section

Here’s what you should include in the Results section:

At each stage and for each group of the study, report the number of participants (if some were lost to follow-up, provide the reasons).
Describe participants’ characteristics.
Compare participants in different groups.
Describe the main variables in the study.
The statistical significance (the p-value).
The precision (the 95% confidence interval).
The practical significance (the effect size).

4.3. Using figures and tables

A table or a figure are useful to highlight important results or to represent a lot of numbers that, if reported in the text, can be unpleasant for the reader.

Here are a few rules regarding figures and tables:

The supporting text should complement the table or figure but not repeat the same content.
The table or figure should stand alone (i.e., the reader can understand it without referring to the text).
No vertical lines.
A line above the header row.
A line below the header row.
A line at the bottom of the table.
No horizontal lines to separate data rows.

(Refer to the example below to see how your tables should look like)

4.4. Verb tense and voice in the Results section

Use the past tense for completed actions.

“In our sample of 9,830 articles, the median title length composed of 16 words (IQR = 6), had 2.2 yearly citations (IQR = 3.33), and was published in a journal with an impact factor of 2.74 (IQR = 1.67).”

Use the present tense for things that continue to be true today.

“The Poisson model shows a significant negative effect of longer titles on citation count.”

Use the active voice when possible.

4.5. Example: writing a Results section

In this section, we are going to verify that the Results section of our example article ( link to the full-text P D F ) follows the structure discussed above. (Remember that this article is about studying the influence of title length on its attractiveness).

What follows is the Results section of this article with the main steps highlighted:

In our sample of 9,830 articles, the median title composed of 16 words (IQR = 6), had 2.2 yearly citations (IQR = 3.33), and was published in a journal with an impact factor of 2.74 (IQR = 1.67). Also, 4,317 (43.9%) of titles contained at least one colon, 1,442 (14.7%) contained at least one comma, and 2,794 (28.4%) mentioned the study design.

The Poisson model shows a significant negative effect of longer titles on citation count (Table 2). Specifically, each additional word in the title causes a drop of 2.5% in the citation rate (95% confidence interval: [-2.7%, -2.3%]; p < 0.001). Equivalently, we can say that removing one word from the title causes an increase of 2.5% in the citation rate. To put that into perspective, removing one word from the title of the median article (that has 2.2 citations per year) causes a gain of 0.055 (= 2.2 × 0.025) citations per year, equivalent to 1 citation every 19 years.

Example of a table format in a research paper

5. Writing the Discussion section

In the Discussion section, you should explain the meaning of your results, their importance, and implications.

5.1. Length of the Discussion section

The Discussion section should be:

820 to 1,480 words long (5 to 9 paragraphs).
The same length as the Methods or the Results, and about double the length of the Introduction.

(These data are based on an analysis I did on 61,517 articles from PubMed )

5.2. Structure of the Discussion section

Here’s what you should include in the Discussion section:

Step #1: Answer the study objective (i.e., where the Introduction ended). Your first sentence can be: “We/I found that” , “This study shows/proves that” , etc.
Explain its consequences.
Comment on whether it supports or refutes your initial hypothesis (i.e., was this result expected or unexpected?).
Compare it with the results of other studies (if they contradict each other: explain why, and suggest a way for further studies to resolve this contradiction).
Then discuss your secondary finding (if you have any) by following the same steps as you did for the main finding.
Step #3: Point out the strengths of your study (e.g., the use of a new and superior method, a larger sample size, etc.).
How you addressed these limitations in your design and analysis (i.e., justify the methods used in your study).
What future studies should do to address these limitations.
Step #5: Conclude with a takeaway message that reminds the reader of your most important finding and its implications (this Conclusion paragraph is sometimes put in a separate section after the Discussion [for more information, see: Length of a Conclusion Section: Analysis of 47,810 Examples ]).

5.3. Verb tense and voice in the Discussion section

Use the past tense for completed actions. For instance:

“I found that…”.

Use the present tense for things that continue to be true today. For instance:

“This study shows that…”.

5.4. Example: writing a Discussion section

In this section, we are going to verify that the Discussion section of our example article ( link to the full-text PDF ) follows the structure discussed above. (Remember that this article is about studying the influence of title length on its attractiveness).

What follows is the Discussion section of this article with the main steps highlighted:

This study shows that shorter research titles are more engaging by proving that they attract more citations. However, this effect, although statistically significant, is practically negligible since removing one word from a title will attract, on average, a single additional citation every 19 years–so I would not recommend shortening research titles as a strategy for increasing the citation count.

Previous studies on the subject reported conflicting results for articles in different disciplines since they did not use a causal approach to control bias and confounding. For instance, they found that shorter titles attracted more citations in psychology (Subotic and Mukherjee, 2014) and general scientific research (Letchford et al., 2015), but less in economics (Guo et al., 2018) and medicine (Jacques and Sebire, 2010; Habibzadeh and Yadollahie, 2010), and had no effect in marketing research (Stremersch et al., 2007) and scientometrics (Falahati Qadimi Fumani et al., 2015). What distinguishes the present study was the use of a causal diagram to identify and block alternative paths between title length and citation count, removing all but the causal explanation of any association between the two.

However, there are some limitations: (1) the 3 million biomedical research articles that are freely available on PubMed Central from which our sample was drawn may not accurately represent all published articles—thus introducing selection bias; (2) adjusting for the journal impact factor instead of the journal itself (to reduce model complexity) may have resulted in some residual confounding; and (3) the general approach taken to adjust for bias and confounding using a causal diagram (Figure 5) created based on my understanding of the subject may have incorporated an element of subjectivity into the analysis. Future studies can address these issues by: (1) collecting data on articles from different disciplines (to increase the result’s generalizability), (2) including a larger number of articles from each journal (to enable adjusting for Journal instead of Journal impact factor ), and (3) validating, either theoretically or analytically, the structure of the causal diagram (to reduce subjectivity).

Finally, this study proves that shortening a research title is not an effective strategy for earning more citations. Yet, writing shorter titles may still have other benefits, such as: getting more reads on Mendeley (Zahedi and Haustein, 2018; Didegah and Thelwall, 2013), tweets (Haustein et al., 2015), appearances in social media in general (Zagovora et al., 2018), and avoiding truncation when they appear on the results page of an online search engine like Google.

6. Writing the Abstract

The Abstract is a summary of the article.

6.1. Length of the Abstract

The Abstract should be 220 to 320 words long (1 to 4 paragraphs).

(These data are based on an analysis I did on 61,429 articles from PubMed )

6.2. Structure of the Abstract

In the Abstract, you should provide a summary of each section of your paper (It can be divided into subheadings, if the journal allows it):

Step #1: Start with a one sentence introduction to the subject.
Step #2: Mention the study objective .
Step #3: Summarize the Methods section .
Step #4: Highlight key results in numbers (including data is important for researchers who want to cite your article based only on the Abstract).
Step #5: End with a one sentence conclusion (i.e., skip the detailed discussion of the results and go straight to the takeaway message).

6.3. Example: writing an Abstract

In this section, we are going to verify that the Abstract of our example article ( link to the full-text PDF ) follows the structure discussed above. (Remember that this article is about studying the influence of title length on its attractiveness).

What follows is the Abstract of this article with the main steps highlighted:

Attractive titles are expected to drive more reads and thus more citations to a research article, so studying the effect of title length on its attractiveness can be reduced to analyzing its influence on the citation count. Previous studies on the subject showed conflicting results that are probably attributable to bias and confounding, since they mostly focused on predicting citation count based on title length instead of using a causal model to explain the relationship between the two. The present study aims to quantify the direct influence of title length on its attractiveness guided by a causal diagram to identify and eliminate alternative explanations such as indirect effects and confounding. The study used data on 9,830 biomedical research articles from PubMed Central, downloaded through an API created by Comeau and colleagues. Poisson regression modeled the citation rate as a function of title length, adjusting for mediators of indirect effects—such as the use of a comma and a colon in the title—and confounders—such as the journal impact factor and the mention of study design in the title. The model shows that each word removed from the title increases the citation rate by 2.5%. This means that, for the median article that receives 2.2 citations per year, each word removed from the title causes a gain of 0.055 citations per year, equivalent to 1 citation every 19 years. Although statistically significant, this effect is practically negligible—so shortening a research title is not an effective strategy for earning more citations.

7. Writing the Title

The last thing one discovers in composing a work is what to put first. Blaise Pascal

The Title’s role is to describe the content of the article and attract people to read it. Remember that only 18% of those who read the title proceed to read the Abstract [Source: Mabe and Amin, 2002 ].

7.1. Length of the Title

The Title should be 11 to 18 words long (80 to 129 characters).

Keep your Title as short as possible, since:

Google shows only the first 60 characters of titles in their results page, so longer titles will be truncated when they appear in Google search.
High-impact journals tend to publish articles with short titles.

(These data are based on an analysis I did on 104,161 titles from PubMed )

7.2. Structure of the Title

The Title should:

Mention the central question or the purpose of the study (including important variables).
Be front loaded : this means that the keywords should be close to the beginning of the title (remember that readers are scanning the title and they want to determine as fast as possible if they are interested in your article).
Have a meaningful short version . For those searching online, Google will show them only the first 60 characters of your title and the rest is truncated. So, make sure to pack enough information in this part for users to be able to judge whether they want to click it.
Mention the study design [optional].
Avoid abbreviations and jargon . For instance: “ The effects of having CVD on the psychological status “ should be replaced by “Psychological effects of cardiovascular disease” .

7.3. Example: writing a Title

The following figure shows how the Title of our example article follows the structure discussed above:

Example of writing a title for a research paper

8. Writing optional sections

8.1. writing the acknowledgement section.

In this section, you should acknowledge any significant technical contribution, permission, advice, suggestion, or comment you received.

“I would like to thank Prof. John for assistance with choosing an appropriate study design”.

“Thanks are due to all the hospital crew members who contributed their time and effort to make the data collection feasible in the shortest time possible”.

8.2. Writing the Funding section

In this section, you should provide the sources of funding, or the sources of the equipment and materials used in the study, and the role of funders.

“The authors received no financial support for the research, authorship, or publication of this article”.

“This work was supported by [name of the funder, and grant number]”.

8.3. Writing the Conflicts of Interest section

In this section, you should state if you have any direct or indirect competing interests that may have influenced the outcome of the study, such as: financial, work, personal, or religious interests.

“The authors declare that they have no conflicts of interest”.

“The corresponding author was a former employee in company X that sells the main product used in this study”.

8.4. Writing the Appendix

In this section, you should provide supplementary information that was too large to be included in the main text, such as: data, questionnaires, and additional details on the materials and methods used.

9. Refining and improving your article

The following is a list of useful tips to improve your writing:

Avoid jargon , be concise, and focus on saving your readers’ time. The truth is that nobody enjoys reading, if readers can download information into their brain, they would!
Assume that your readers are beginners : so, use terms that are easy to understand.
Avoid acronyms when possible.
You don’t know the subject.
You don’t want to repeat the pronouns ”I” or ”We” in many places in the same paragraph (although it would be fine to use them sparingly, see: ”I” & ”We” in Academic Writing: Examples from 9,830 Studies ).
You want to emphasize what was done instead of who did it (especially in the Methods section).
To maintain the flow of ideas (for more information, see the video lecture by Steven Pinker below).
Write short sentences and paragraphs : each paragraph should be between 2 and 6 sentences long (65 to 167 words), and should cover a single topic. (For more information, see: Paragraph Length: Data from 9,830 Research Papers )
Get rid of hedge words : e.g. ”These results might suggest that a fair amount of x is suspected to have a meaningful impact on y” . These make you sound hesitant or unsure about what you are talking about.
Avoid using “They” or “Their” when the subject is singular . For a gender-neutral language, revise the sentence to make the subject plural. For instance, use: “Participants were assigned according to their choosing” instead of “Each participant was assigned according to their choosing” .

For more writing tips, I highly recommend this lecture by Steven Pinker:

10. Managing and formatting your References

When it comes to references, you should:

Cite between 25 and 56 references overall (approximately 1 reference for every 95 words or 4 sentences) [Source: How Many References Should a Research Paper Have? Study of 96,685 Articles ].
Aim to find those published within the past 13 years [Source: How Old Should Your Article References Be? Based on 3,823,919 Examples ].
Cite the original source, not secondary sources.
Cite research papers and books instead of websites and videos (unless these contained original data not available elsewhere).
Use a citation management software to collect and organize your references. I recommend Zotero® since it is free, easy to learn, and has a lot of tutorials online.

11. Submitting your article

Here’s a step-by-step description of how to find a journal and submit your article:

Go to: The Directory of Open Access Journals (This is a database of 17,614 journals that publish open-access articles–i.e., if you publish in these journals, your article’s full-text will be available for free to your readers).
Under SEE JOURNALS, select: Without article processing charges in order to exclude journal where you have to pay to publish your article.
Under SUBJECTS, choose: the domain that is closest to the topic of your article.
Under LANGUAGES, select: English.
Select a journal from the suggested list.
Go to the journal’s website, look for their “Instructions for authors”, and format your article accordingly.
Sign-up to their website and submit your article.

Once your article is submitted, the editor takes a look at it and may:

The topic of your article is not interesting for the journal’s audience.
Your work is not important enough to be published in that journal.
Rejected: In this case, you have to send your article to another journal (don’t get discouraged by rejection, sometimes important articles get rejected).
Rejected, but can be resubmitted after making some major changes suggested by the reviewers (for instance, expanding, deleting, or re-writing major parts of the article): in this case, you can either revise and resubmit, or look for another journal.
Accepted, but needs minor changes.
Accepted (without the need for changes).

When you want to revise and resubmit your article, you should prepare 2 things:

A revised manuscript with all the modifications you made highlighted (to make it easy for the reviewers to see what you changed).
A response for the reviewers where you address their comments point by point: you can either agree or disagree with their recommendations (but, in case you disagree, you should explain the reason).

Once your paper is accepted, you will get a final version formatted in the journal’s style. Be careful to look for errors before you accept this final version.

Manan Sahni

List of 10 Book Binding methods that you must know

How to Write and Publish a Research Paper for a Peer-Reviewed Journal

Affiliations.

1 Department of Maternal and Child Health, University of North Carolina Gillings School of Global Public Health, 135 Dauer Dr, 27599, Chapel Hill, NC, USA.
2 Department of Maternal and Child Health, University of North Carolina Gillings School of Global Public Health, 135 Dauer Dr, 27599, Chapel Hill, NC, USA. [email protected].
3 Department of Epidemiology, University of Michigan School of Public Health, 1415 Washington Heights, Ann Arbor, MI, 48109-2029, USA. [email protected].
PMID: 32356250
PMCID: PMC8520870
DOI: 10.1007/s13187-020-01751-z

Communicating research findings is an essential step in the research process. Often, peer-reviewed journals are the forum for such communication, yet many researchers are never taught how to write a publishable scientific paper. In this article, we explain the basic structure of a scientific paper and describe the information that should be included in each section. We also identify common pitfalls for each section and recommend strategies to avoid them. Further, we give advice about target journal selection and authorship. In the online resource 1, we provide an example of a high-quality scientific paper, with annotations identifying the elements we describe in this article.

Keywords: Manuscripts; Publishing; Scientific writing.

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Google helped make an exquisitely detailed map of a tiny piece of the human brain

A small brain sample was sliced into 5,000 pieces, and machine learning helped stitch it back together.

Cassandra Willyard archive page

A team led by scientists from Harvard and Google has created a 3D, nanoscale-resolution map of a single cubic millimeter of the human brain. Although the map covers just a fraction of the organ—a whole brain is a million times larger—that piece contains roughly 57,000 cells, about 230 millimeters of blood vessels, and nearly 150 million synapses. It is currently the highest-resolution picture of the human brain ever created.

To make a map this finely detailed, the team had to cut the tissue sample into 5,000 slices and scan them with a high-speed electron microscope. Then they used a machine-learning model to help electronically stitch the slices back together and label the features. The raw data set alone took up 1.4 petabytes. “It’s probably the most computer-intensive work in all of neuroscience,” says Michael Hawrylycz, a computational neuroscientist at the Allen Institute for Brain Science, who was not involved in the research. “There is a Herculean amount of work involved.”

Many other brain atlases exist, but most provide much lower-resolution data. At the nanoscale, researchers can trace the brain’s wiring one neuron at a time to the synapses, the places where they connect. “To really understand how the human brain works, how it processes information, how it stores memories, we will ultimately need a map that’s at that resolution,” says Viren Jain, a senior research scientist at Google and coauthor on the paper, published in Science on May 9 . The data set itself and a preprint version of this paper were released in 2021 .

Brain atlases come in many forms. Some reveal how the cells are organized. Others cover gene expression. This one focuses on connections between cells, a field called “connectomics.” The outermost layer of the brain contains roughly 16 billion neurons that link up with each other to form trillions of connections. A single neuron might receive information from hundreds or even thousands of other neurons and send information to a similar number. That makes tracing these connections an exceedingly complex task, even in just a small piece of the brain..

To create this map, the team faced a number of hurdles. The first problem was finding a sample of brain tissue. The brain deteriorates quickly after death, so cadaver tissue doesn’t work. Instead, the team used a piece of tissue removed from a woman with epilepsy during brain surgery that was meant to help control her seizures.

Once the researchers had the sample, they had to carefully preserve it in resin so that it could be cut into slices, each about a thousandth the thickness of a human hair. Then they imaged the sections using a high-speed electron microscope designed specifically for this project.

Next came the computational challenge. “You have all of these wires traversing everywhere in three dimensions, making all kinds of different connections,” Jain says. The team at Google used a machine-learning model to stitch the slices back together, align each one with the next, color-code the wiring, and find the connections. This is harder than it might seem. “If you make a single mistake, then all of the connections attached to that wire are now incorrect,” Jain says.

“The ability to get this deep a reconstruction of any human brain sample is an important advance,” says Seth Ament, a neuroscientist at the University of Maryland. The map is “the closest to the ground truth that we can get right now.” But he also cautions that it’s a single brain specimen taken from a single individual.

The map, which is freely available at a web platform called Neuroglancer , is meant to be a resource other researchers can use to make their own discoveries. “Now anybody who’s interested in studying the human cortex in this level of detail can go into the data themselves. They can proofread certain structures to make sure everything is correct, and then publish their own findings,” Jain says. (The preprint has already been cited at least 136 times .)

The team has already identified some surprises. For example, some of the long tendrils that carry signals from one neuron to the next formed “whorls,” spots where they twirled around themselves. Axons typically form a single synapse to transmit information to the next cell. The team identified single axons that formed repeated connections—in some cases, 50 separate synapses. Why that might be isn’t yet clear, but the strong bonds could help facilitate very quick or strong reactions to certain stimuli, Jain says. “It’s a very simple finding about the organization of the human cortex,” he says. But “we didn’t know this before because we didn’t have maps at this resolution.”

The data set was full of surprises, says Jeff Lichtman, a neuroscientist at Harvard University who helped lead the research. “There were just so many things in it that were incompatible with what you would read in a textbook.” The researchers may not have explanations for what they’re seeing, but they have plenty of new questions: “That’s the way science moves forward.”

Biotechnology and health

How scientists traced a mysterious covid case back to six toilets.

When wastewater surveillance turns into a hunt for a single infected individual, the ethics get tricky.

An AI-driven “factory of drugs” claims to have hit a big milestone

Insilico is part of a wave of companies betting on AI as the "next amazing revolution" in biology

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The quest to legitimize longevity medicine

Longevity clinics offer a mix of services that largely cater to the wealthy. Now there’s a push to establish their work as a credible medical field.

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There is a new most expensive drug in the world. Price tag: $4.25 million

But will the latest gene therapy suffer the curse of the costliest drug?

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09 May 2024

Cubic millimetre of brain mapped in spectacular detail

Carissa Wong

You can also search for this author in PubMed Google Scholar

Rendering based on electron-microscope data, showing the positions of neurons in a fragment of the brain cortex. Neurons are coloured according to size. Credit: Google Research & Lichtman Lab (Harvard University). Renderings by D. Berger (Harvard University)

Researchers have mapped a tiny piece of the human brain in astonishing detail. The resulting cell atlas, which was described today in Science 1 and is available online , reveals new patterns of connections between brain cells called neurons, as well as cells that wrap around themselves to form knots, and pairs of neurons that are almost mirror images of each other.

The 3D map covers a volume of about one cubic millimetre, one-millionth of a whole brain, and contains roughly 57,000 cells and 150 million synapses — the connections between neurons. It incorporates a colossal 1.4 petabytes of data. “It’s a little bit humbling,” says Viren Jain, a neuroscientist at Google in Mountain View, California, and a co-author of the paper. “How are we ever going to really come to terms with all this complexity?”

Slivers of brain

The brain fragment was taken from a 45-year-old woman when she underwent surgery to treat her epilepsy. It came from the cortex, a part of the brain involved in learning, problem-solving and processing sensory signals. The sample was immersed in preservatives and stained with heavy metals to make the cells easier to see. Neuroscientist Jeff Lichtman at Harvard University in Cambridge, Massachusetts, and his colleagues then cut the sample into around 5,000 slices — each just 34 nanometres thick — that could be imaged using electron microscopes.

Jain’s team then built artificial-intelligence models that were able to stitch the microscope images together to reconstruct the whole sample in 3D. “I remember this moment, going into the map and looking at one individual synapse from this woman’s brain, and then zooming out into these other millions of pixels,” says Jain. “It felt sort of spiritual.”

Rendering of a neuron with a round base and many branches, on a black background.

A single neuron (white) shown with 5,600 of the axons (blue) that connect to it. The synapses that make these connections are shown in green. Credit: Google Research & Lichtman Lab (Harvard University). Renderings by D. Berger (Harvard University)

When examining the model in detail, the researchers discovered unconventional neurons, including some that made up to 50 connections with each other. “In general, you would find a couple of connections at most between two neurons,” says Jain. Elsewhere, the model showed neurons with tendrils that formed knots around themselves. “Nobody had seen anything like this before,” Jain adds.

The team also found pairs of neurons that were near-perfect mirror images of each other. “We found two groups that would send their dendrites in two different directions, and sometimes there was a kind of mirror symmetry,” Jain says. It is unclear what role these features have in the brain.

Proofreaders needed

The map is so large that most of it has yet to be manually checked, and it could still contain errors created by the process of stitching so many images together. “Hundreds of cells have been ‘proofread’, but that’s obviously a few per cent of the 50,000 cells in there,” says Jain. He hopes that others will help to proofread parts of the map they are interested in. The team plans to produce similar maps of brain samples from other people — but a map of the entire brain is unlikely in the next few decades, he says.

“This paper is really the tour de force creation of a human cortex data set,” says Hongkui Zeng, director of the Allen Institute for Brain Science in Seattle. The vast amount of data that has been made freely accessible will “allow the community to look deeper into the micro-circuitry in the human cortex”, she adds.

Gaining a deeper understanding of how the cortex works could offer clues about how to treat some psychiatric and neurodegenerative diseases. “This map provides unprecedented details that can unveil new rules of neural connections and help to decipher the inner working of the human brain,” says Yongsoo Kim, a neuroscientist at Pennsylvania State University in Hershey.

doi: https://doi.org/10.1038/d41586-024-01387-9

Shapson-Coe, A. et al. Science 384 , eadk4858 (2024).

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How to Publish a Research Paper
To Publish a Research Paper follow the guide below: Conduct original research: Conduct thorough research on a specific topic or problem. Collect data, analyze it, and draw conclusions based on your findings. Write the paper: Write a detailed paper describing your research.
How to Publish a Research Paper: A Step-by-Step Guide
Step 2: Finding the Right Journal. Understanding how to publish a research paper involves selecting the appropriate journal for your work. This step is critical for successful publication, and you should take several factors into account when deciding which journal to apply for: Conduct thorough research to identify journals that specialise in ...
How to Publish a Research Paper: Your Step-by-Step Guide
3. Submit your article according to the journal's submission guidelines. Go to the "author's guide" (or similar) on the journal's website to review its submission requirements. Once you are satisfied that your paper meets all of the guidelines, submit the paper through the appropriate channels.
Publish with Elsevier: Step by step
4. Track your paper. 5. Share and promote. 1. Find a journal. Find out the journals that could be best suited for publishing your research. For a comprehensive list of Elsevier journals check our Journal Catalog. You can also match your manuscript using the JournalFinder tool, then learn more about each journal.
How to publish your research
Step 1: Choosing a journal. Why choose your target journal before you start writing? Choosing which journal to publish your research paper in is one of the most significant decisions you have to make as a researcher. Where you decide to submit your work can make a big difference to the reach and impact your research has.
How to Write and Publish a Research Paper in 7 Steps
This post will discuss 7 steps to the successful publication of your research paper: Check whether your research is publication-ready. Choose an article type. Choose a journal. Construct your paper. Decide the order of authors. Check and double-check. Submit your paper. 1.
7 steps to publishing in a scientific journal
Sun and Linton (2014), Hierons (2016) and Craig (2010) offer useful discussions on the subject of "desk rejections.". 4. Make a good first impression with your title and abstract. The title and abstract are incredibly important components of a manuscript as they are the first elements a journal editor sees.
How to Write and Publish a Research Paper for a Peer ...
Communicating research findings is an essential step in the research process. Often, peer-reviewed journals are the forum for such communication, yet many researchers are never taught how to write a publishable scientific paper. In this article, we explain the basic structure of a scientific paper and describe the information that should be included in each section. We also identify common ...
Understanding the Publishing Process
The publication process explained. The path to publication can be unsettling when you're unsure what's happening with your paper. Learn about staple journal workflows to see the detailed steps required for ensuring a rigorous and ethical publication. Your team has prepared the paper, written a cover letter and completed the submission form.
How to Write and Publish a Research Paper for a Peer-Reviewed Journal
The introduction section should be approximately three to five paragraphs in length. Look at examples from your target journal to decide the appropriate length. This section should include the elements shown in Fig. 1. Begin with a general context, narrowing to the specific focus of the paper.
PDF How to Write and Publish a Scientiﬁc Paper
of the research; and additional material on international aspects of scientiﬁc writing. ... 978-1-107-67074-7 - How to Write and Publish a Scientific Paper: Seventh Edition Robert A. Day and Barbara Gastel Frontmatter More information. Contents xi Presentation of the Paper 174 Slides 175
How to publish an article?
Production. - Copy editing and language polishing. - Data processing and type setting. - Article Tracking. - Checking your article: proofing procedure. - e.Proofing - Makes editing easy! Read more. Publication. - Publishing your article "Online First".
Writing the paper
Writing tips. Avoid fragmentation (breaking a single study into multiple short papers) and redundant publication (submitting multiple papers that are very similar). When writing a scientific paper, think about the structure familiar to you from reading scientific papers. A common structure for scientific research articles is termed IMRAD ...
How To Write And Publish A Scientific Manuscript
A clinician should continuously strive to increase knowledge by reviewing and critiquing papers, thoughtfully considering how to integrate new data into practice. This is the essence of evidence-based medicine (EBM).[1] When new clinical queries arise, one should seek answers in the published literature. The ability to read a scientific or medical manuscript remains vitally important ...
How to Write a Research Paper
To publish your research paper, find a target publication, thoroughly read their guidelines, format your paper accordingly, and send it to them per their instructions. You may need to include a cover letter, too. After submission, your paper may be peer-reviewed by experts to assess its legitimacy, quality, originality, and methodology. ...
PDF How to Write a Good Research Paper
3 or 4 data sets per figure; well-selected scales; appropriate axis label size; symbols clear to read; data sets easily distinguishable. Each photograph must have a scale marker of professional quality in a corner. Use color ONLY when necessary. Color must be visible and distinguishable when printed in black & white.
How to publish your paper
A. Yes, instead of giving the volume and page number, you can give the paper's DOI at the end of the citation. For example, Nature papers should be cited in the form; Author (s) Nature advance ...
How to Write & Publish a Research Paper: Step-by-Step Guide
Here's what you should include in the Introduction: Step #1: Describe the general context of your work (your aim should be to convince the reader that the topic of your research is interesting). Step #2: Summarize the results of previous studies on the topic (report what others have found and provide references.
PDF How to Write and Publish a Research Paper for a Peer ...
Look at examples from your target journal to decide the appropriate length. This section should include the elements shown in Fig. 1. Begin with a general context, narrowing to the specific focus of the pa-per. Include five main elements: why your research is im-portant, what is already known about the topic, the gap.
How to Publish a Research Paper: A Complete Guide
Here's a list of steps to keep in mind before publishing a research paper : Step 1: Identifying the Right Journal. Step 2: Preparing Step 3: Your Manuscript. Step 3: Conducting a Thorough Review. Step 4: Writing a Compelling Cover Letter. Step 5: Navigating the Peer Review Process. Step 6: Handling Rejections.
How to Write and Publish a Research Paper for a Peer-Reviewed ...
Abstract. Communicating research findings is an essential step in the research process. Often, peer-reviewed journals are the forum for such communication, yet many researchers are never taught how to write a publishable scientific paper. In this article, we explain the basic structure of a scientific paper and describe the information that ...
How to Write a Research Paper
Create a research paper outline. Write a first draft of the research paper. Write the introduction. Write a compelling body of text. Write the conclusion. The second draft. The revision process. Research paper checklist.
How to publish a research paper?
1. Your paper: Must be current and must follow the six steps of Scientific research. ( problem, question, hypothesis, methodology, results, conclusion and so on) 2. Make sure to ask a scholar to ...
Get Support for Research & Publishing
Make an appointment with a library liaison to get the help you need to get your work done. Many of Harvard's professional schools offer specialized support for data services in certain disciplines. Publishing Data Services at Countway Library Countway Library Review Service. Research Data Program at Baker Library. Show More.
A Guide on How to Write an Abstract for a Research Paper
Use strong action verbs to describe the effect of your research, such as "transforms," "enables," "revolutionizes," or "underscores.". 5. Keep it concise. Focus on writing within the word limit and keeping the information that is required to be showcased or highlighted. After drafting your abstract, review it specifically for ...
Judging the relative trustworthiness of research results: How to do it
Sadly, this is rare. There is widespread evidence of dishonesty in research publishing, from the existence of 'paper mills' to individuals making up or suppressing data, and in all fields apparently (Ioannidis, 2021; Sabel et al., 2023). There is also considerable publication bias, with larger and more positive outcomes apparently being ...
Google helped make an exquisitely detailed map of a tiny piece of the
Google Research & Lichtman Lab, Harvard University / D. Berger (rendering) ... a senior research scientist at Google and coauthor on the paper, published in Science on May 9.
2024 AP Exam Dates
2024 AP Exam Dates. The 2024 AP Exams will be administered in schools over two weeks in May: May 6-10 and May 13-17. AP coordinators are responsible for notifying students when and where to report for the exams. Early testing or testing at times other than those published by College Board is not permitted under any circumstances.
A petavoxel fragment of human cerebral cortex reconstructed at ...
A complete understanding of the human brain begins with elucidation of its structural properties at a subcellular level. To provide a valuable resource for the scientific community and to better understand the structure of the human temporal cortex, Shapson-Coe et al. performed an electron microscopy reconstruction of a cubic millimeter of human temporal cortex.
Cubic millimetre of brain mapped in spectacular detail
Credit: Google Research & Lichtman Lab (Harvard University). Renderings by D. Berger (Harvard University) Researchers have mapped a tiny piece of the human brain in astonishing detail.

How to Publish a Research Paper: A Step-by-Step Guide

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Understanding the Publishing Process

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